Biochemical Basis of Functional Neuroteratology: Permanent Effects of Chemicals on the Developing Brain

Content: 
List of Contributors
Pages v-vi

Preface
Pages vi-vii

Acknowledgements
Page ix

Concept of functional neuroteratology and the importance of neurochemistry Original Research Article
Pages 3-14
Dick F. Swaab, Gerard J. Boer, Matthijs G.P. Feenstra

Defects of neuronal migration and the pathogenesis of cortical malformations Original Research Article
Pages 15-37
Pasko Rakic, D.F. Swaab

Implications of behavioral teratology for assessing the risks posed by environmental and therapeutic chemicals Original Research Article
Pages 39-49
Bernard Weiss

Problems in studying functional teratogenicity in man Original Research Article
Pages 51-58
Hendrik J. Huisjes

Behavioural teratology of exogenous substances: regulation aspects Original Research Article
Pages 59-67
Herman B.W.M. Koëter

Teratogenic mechanisms of dysthyroidism in the central nervous system Original Research Article
Pages 71-86
Andrea Vaccari

The role of the insulin-like growth factors in the regulation of brain development Original Research Article
Pages 87-99
Vicki R. Sara, Christine Carlsson-Skwirut

Stress, glucocorticoids and development Original Research Article
Pages 101-120
E. Ronald De Kloet, Patricia Rosenfeld, J. Anke M. Van Eekelen, Winardi Sutanto, Seymour Levine

Actions of sex hormones on the brain: ‘organization’ and ‘activation’ in relation to functional teratology Original Research Article
Pages 121-134
Bruce S. McEwen

Prenatal adverse effects of nicotine on the developing brain Original Research Article
Pages 137-157
Walter Lichtensteiger, Urs Ribary, Margret Schlumpf, Brigitte Odermatt, Hans Rudolf Widmer

Functional deprivation of noradrenaline neurotransmission: effects of clonidine on brain development Original Research Article
Pages 159-172
Majid Mirmiran, Matthijs G.P. Feenstra, Fred A. Dijcks, Nico P.A. Bos, Frans Van Haaren

Long-lasting changes after perinatal exposure to antidepressants Original Research Article
Pages 173-187
Joaquín Del Río, Dolores Montero, María L. De Ceballos

Placental and blood element neurotransmitter receptor regulation in humans: potential models for studying neurochemical mechanisms underlying behavioral teratology Original Research Article
Pages 189-205
Bruce D. Perry

Benzodiazepines: influence on the developing brain Original Research Article
Pages 207-228
Carol K. Kellogg

Anticonvulsants and brain development Original Research Article
Pages 229-244
Charles V. Vorhees, Daniel R. Minck, Helen K. Berry

Neuropeptides and functional neuroteratology Original Research Article
Pages 245-264
Gerard J. Boer, Frank G.M. Snijdewint, Dick F. Swaab

Perinatal exposure to methadone: how do early biochemical alterations cause neurofunctional disturbances? Original Research Article
Pages 265-279
Theodore A. Slotkin

Excitotoxic food additives: functional teratological aspects Original Research Article
Pages 283-294
John W. Olney

Organometals and brain development Original Research Article
Pages 295-303
Zoltan Annau

Alcohol as a social teratogen Original Research Article
Pages 305-317
Brian E. Leonard

Prenatal stress effects on functional development of the offspring Original Research Article
Pages 319-331
Marta Weinstock, Ester Fride, Raya Hertzberg

Structural-functional relationships in experimentally induced brain damage Original Research Article
Pages 335-348
Patricia M. Rodier

Coordination of cell development by the ornithine decarboxylase (ODC)/polyamine pathway as an underlying mechanism in developmental neurotoxic events Original Research Article
Pages 349-363
Joanne M. Bell, Theodore A. Slotkin

Neurotransmitters as morphogens Original Research Article
Pages 365-387
Jean M. Lauder

Brain cell acquisition and neurotropic drugs with special reference to functional teratogenesis Original Research Article
Pages 389-403
Ambrish J. Patel, Paul D. Lewis

Reorganization of noradrenergic neuronal systems following neonatal chemical and surgical injury Original Research Article
Pages 405-423
Richard M. Kostrzewa

Use of toxins to disrupt neurotransmitter circuitry in the developing brain Original Research Article
Pages 425-446
Michael V. Johnston, John Barks, Timothy Greenamyre, Faye Silverstein

Metabolic imbalance and nerve cell damage in the brain Original Research Article
Pages 447-463
Robert Balázs

Humoral and surface-anchored factors in development and repair of the nervous system Original Research Article
Pages 465-489
Silvio Varon, Brigitte Pettmann, Marston Manthorpe

Gangliosides as cell adhesion factors in the formation of selective connections within the nervous system Original Research Article
Pages 491-508
Robert E. Baker

Prenatal neurotransmitter programming of postnatal receptor function Original Research Article
Pages 509-522
Jeannette C. Miller, Arnold J. Friedhoff

Neuropeptide influences on the development of their receptors Original Research Article
Pages 523-533
Gail E. Handelmann

Transgenerational effects of drug and hormonal treatments in mammals: a review of observations and ideas Original Research Article
Pages 535-553
John H. Campbell, Penny Perkins