Basic Methods Handbook for Clinical Orthopaedic Research: A Practical Guide and Case Based Research Approach

Front Matter ....Pages i-xiv
Front Matter ....Pages 1-1
 What Is Evidence-Based Medicine?  (Eleonor Svantesson, Eric Hamrin Senorski, Jón Karlsson, Olufemi R. Ayeni, Kristian Samuelsson)....Pages 3-10
 What Is the Hierarchy of Clinical Evidence?  (Vishal S. Desai, Christopher L. Camp, Aaron J. Krych)....Pages 11-22
 Bias and Confounding  (Naomi Roselaar, Magaly Iñiguez Cuadra, Stephen Lyman)....Pages 23-32
 Ethical Consideration in Orthopedic Research  (Jason L. Koh, Diego Villacis)....Pages 33-42
 Conflict of Interest  (Michael Hantes, Apostolos Fyllos)....Pages 43-47
 Ethics in Clinical Research  (Naomi Roselaar, Niv Marom, Robert G. Marx)....Pages 49-54
Front Matter ....Pages 55-55
 How to Get Started: From Idea to Research Question  (Lachlan M. Batty, Timothy Lording, Eugene T. Ek)....Pages 57-63
 How to Write a Study Protocol  (Lukas B. Moser, Michael T. Hirschmann)....Pages 65-73
 The Ethical Approval Process  (Karren Takamura, Frank Petrigliano)....Pages 75-81
 How to Assess Patient’s Outcome?  (Yuichi Hoshino, Alfonso Barnechea)....Pages 83-88
 Basics of Outcome Assessment in Clinical Research  (Monique C. Chambers, Sarah M. Tepe, Lorraine A. T. Boakye, MaCalus V. Hogan)....Pages 89-95
 Types of Scoring Instruments Available  (José F. Vega, Kurt P. Spindler)....Pages 97-109
 Health Measurement Development and Interpretation  (Andrew Firth, Dianne Bryant, Jacques Menetrey, Alan Getgood)....Pages 111-120
 How to Document a Clinical Study and Avoid Common Mistakes in Study Conduct?  (Caroline Mouton, Laura De Girolamo, Daniel Theisen, Romain Seil)....Pages 121-132
 Framework for Selecting Clinical Outcomes for Clinical Trials  (Adam J. Popchak, Andrew D. Lynch, James J. Irrgang)....Pages 133-142
 Advances in Measuring Patient-Reported Outcomes: Use of Item Response Theory and Computer Adaptive Tests  (Andrew D. Lynch, Adam J. Popchak, James J. Irrgang)....Pages 143-150
Front Matter ....Pages 151-151
 Common Statistical Tests  (Stephan Bodkin, Joe Hart, Brian C. Werner)....Pages 153-161
 The Nature of Data  (Clair Smith)....Pages 163-170
 Does No Difference Really Mean No Difference?  (Carola F. van Eck, Marcio Bottene Villa Albers, Andrew J. Sheean, Freddie H. Fu)....Pages 171-183
 Power and Sample Size  (Stephen Lyman)....Pages 185-191
 Visualizing Data  (Stephen Lyman, Naomi Roselaar, Chisa Hidaka)....Pages 193-206
Front Matter ....Pages 207-207
 How to Prepare an Abstract  (Elmar Herbst, Brian Forsythe, Avinesh Agarwalla, Sebastian Kopf)....Pages 209-217
 How to Make a Good Poster Presentation  (Baris Kocaoglu, Paulo Henrique Araujo, Carola Francisca van Eck)....Pages 219-225
 How to Prepare a Paper Presentation?  (Timothy Lording, Jacques Menetrey)....Pages 227-233
 How to Write a Clinical Paper  (Brendan Coleman)....Pages 235-242
 How to Write a Book Chapter  (Thomas R. Pfeiffer, Daniel Guenther)....Pages 243-247
 How to Write a Winning Clinical Research Proposal?  (Christian Lattermann, Janey D. Whalen)....Pages 249-254
 How to Review a Clinical Research Paper?  (Neel K. Patel, Marco Yeung, Kanto Nagai, Volker Musahl)....Pages 255-262
Front Matter ....Pages 263-263
 Level 1 Evidence: A Prospective Randomized Controlled Study  (Seper Ekhtiari, Raman Mundi, Vickas Khanna, Mohit Bhandari)....Pages 265-283
 Level 1 Evidence: Long-Term Clinical Results  (Daisuke Araki, Ryosuke Kuroda)....Pages 285-287
 Level 2 Evidence: Prospective Cohort Study  (Naomi Roselaar, Niv Marom, Robert G. Marx)....Pages 289-293
 Level III Evidence: A Case-Control Study  (Andrew D. Lynch, Adam J. Popchak, James J. Irrgang)....Pages 295-300
 Level 4 Evidence: Clinical Case Series  (Mitchell I. Kennedy, Robert F. LaPrade)....Pages 301-305
 How to Perform a Clinical Study: Level 4 Evidence—Case Report  (Andrew J. Sheean, Gregory V. Gasbarro, Nasef M. N. Abedelatif, Volker Musahl)....Pages 307-312
 Level 5: Evidence  (Seán Mc Auliffe, Pieter D’Hooghe)....Pages 313-319
Front Matter ....Pages 321-321
 Type of Review and How to Get Started  (Matthew Skelly, Andrew Duong, Nicole Simunovic, Olufemi R. Ayeni)....Pages 323-327
Front Matter ....Pages 329-329
 What Is the Difference Between a Systematic Review and a Meta-analysis?  (Shakib Akhter, Thierry Pauyo, Moin Khan)....Pages 331-342
 Reliability Studies and Surveys  (Kelsey L. Wise, Brandon J. Kelly, Michael L. Knudsen, Jeffrey A. Macalena)....Pages 343-358
 Registries  (R. Kyle Martin, Andreas Persson, Håvard Visnes, Lars Engebretsen)....Pages 359-369
Front Matter ....Pages 371-371
 How to Perform an Economic Healthcare Study  (Jonathan Edgington, Xander Kerman, Lewis Shi, Jason L. Koh)....Pages 373-380
Front Matter ....Pages 381-381
 Conducting Multicenter Cohort Studies: Lessons from MOON  (José F. Vega, Kurt P. Spindler)....Pages 383-389
 MARS: The Why and How of It  (Rick W. Wright, Amanda K. Haas, Laura J. Huston)....Pages 391-402
 Multicenter Study: How to Pull It Off? The PIVOT Trial  (Eleonor Svantesson, Eric Hamrin Senorski, Alicia Oostdyk, Yuichi Hoshino, Kristian Samuelsson, Volker Musahl)....Pages 403-413
 Conducting a Multicenter Trial: Learning from the JUPITER (Justifying Patellar Instability Treatment by Early Results) Experience  (Jason L. Koh, Shital Parikh, Beth Shubin Stein, The JUPITER Group)....Pages 415-425
 How to Organise an International Register in Compliance with the European GDPR: Walking in the Footsteps of the PAMI Project (Paediatric ACL Monitoring Initiative)  (Daniel Theisen, Håvard Moksnes, Cyrille Hardy, Lars Engebretsen, Romain Seil)....Pages 427-434
Front Matter ....Pages 435-435
 Common Scales and Checklists in Sports Medicine Research  (Alberto Grassi, Luca Macchiarola, Marco Casali, Ilaria Cucurnia, Stefano Zaffagnini)....Pages 437-470
 A Practical Guide to Writing (and Understanding) a Scientific Paper: Meta-Analyses  (Alberto Grassi, Riccardo Compagnoni, Kristian Samuelsson, Pietro Randelli, Corrado Bait, Stefano Zaffagnini)....Pages 471-497
 A Practical Guide to Writing (and Understanding) a Scientific Paper: Clinical Studies  (Riccardo Compagnoni, Alberto Grassi, Stefano Zaffagnini, Corrado Bait, Kristian Samuelsson, Alessandra Menon et al.)....Pages 499-505
 Reporting Complications in Orthopaedic Trials  (S. Goldhahn, Norimasa Nakamura, J. Goldhahn)....Pages 507-513
 Understanding and Addressing Regulatory Concerns in Research  (Jason L. Koh, Denise Gottfried, Daniel R. Lee, Sandra Navarrete)....Pages 515-531
 What Is Needed to Make Collaboration Work?  (Richard E. Debski, Gerald A. Ferrer)....Pages 533-536
 A Clinical Practice Guideline  (Aleksei Dingel, Jayson Murray, James Carey, Deborah Cummins, Kevin Shea)....Pages 537-549
 How to Navigate a Scientific Meeting and Make It Worthwhile? A Guide for Young Orthopedic Surgeons  (Darren de SA, Jayson Lian, Conor I. Murphy, Ravi Vaswani, Volker Musahl)....Pages 551-560
 How to Write a Scientific Article  (Lukas B. Moser, Michael T. Hirschmann)....Pages 561-578
 Common Mistakes in Manuscript Writing and How to Avoid Them  (Eleonor Svantesson, Eric Hamrin Senorski, Kristian Samuelsson, Jón Karlsson)....Pages 579-584