Autophagy in Health and Disease: Potential Therapeutic Approaches

Front Matter ....Pages i-xi
 Autophagy and Stem Cells  (Kai Li, Zhuo Yang)....Pages 1-20
 Fine-Tuning the Stem Cell Fate by Autophagy  (Shalmoli Bhattacharyya, Ajay Kumar)....Pages 21-29
 Role of Autophagy in Aging of Hematopoietic Stem Cells and Their Niche: Relevance in Clinical Transplantations and Regenerative Medicine  (Rohan S. Kulkarni, Manmohan Bajaj, Vaijayanti P. Kale)....Pages 31-45
 Forkhead Box O (FoxO) Transcription Factors in Autophagy, Metabolic Health, and Tissue Homeostasis  (Longhua Liu, Zhiyong Cheng)....Pages 47-69
 The Role of mTOR in Osteoclasts  (Ralph A. Zirngibl, Irina Voronov)....Pages 71-85
 Apoptotic Cell Clearance in Gut Tissue: Role of Intestinal Regeneration  (Yasunao Numata, Daisuke Hirayama, Kohei Wagatsuma, Tomoya Iida, Hiroshi Nakase)....Pages 87-100
 Autophagic Regulation of Cardiomyocyte Survival and Heart Regeneration  (Toshihiko Aki, Kanako Noritake, Kana Unuma, Koichi Uemura)....Pages 101-118
 The Role of Autophagy in Mesenchymal Stem Cell-Based Suppression of Immune Response  (Vladislav Volarevic, Jelena Jakovljevic, C. Randall Harrell, Crissy Fellabaum, Nebojsa Arsenijevic)....Pages 119-133
 Emerging Connections: Synaptic Autophagy in Brain Aging and Disease  (YongTian Liang)....Pages 135-152
 Virus and Autophagy: Enemies or Allies  (José A. Boga, Zulema Pérez-Martínez, Ana Coto-Montes, Marta E. Alvarez-Argüelles, Russel J. Reiter)....Pages 153-161
 Cancer Stem Cells and Autophagy: Present Knowledge and Future Perspectives  (Bakiye Goker Bagca, Cigir Biray Avci)....Pages 163-177