Arthritis: Models and Mechanisms

Front Matter....Pages I-XIV
Front Matter....Pages 1-1
Infectious Agents in the Pathogenesis of Arthritis Syndromes....Pages 3-11
The Different Phases of Erysipelothrix Polyarthritis: Comparison with Other Microbial Models....Pages 12-23
Arthropathic Properties of Peptidoglycan-Polysaccharide Complexes of Microbial Origin....Pages 24-38
Adjuvant Arthritis: The Role of Microbial Cell Wall Products and Other Substances in the Genesis of Joint Disease in Rats....Pages 39-50
Discussion: Microbes and Microbial Products in the Pathogenesis of Rheumatoid Inflammation....Pages 51-52
 Erysipelothrix rhusiopathiae -lnduced Chronic Polyarthritis in the Dog....Pages 53-57
Neuraminidase and Other Enzymes of Erysipelothrix rhusiopathiae as Possible Pathogenic Factors....Pages 58-67
 Mycoplasma arthritidis -Induced Polyarthritis in Rats....Pages 68-72
Front Matter....Pages 73-73
Protracted Shock — A Pathogenetic Factor in Vasculitis and Connective Tissue Proliferation in Animal Models....Pages 75-86
Pathogenesis of Shock-Induced Pulmonary Fibrosis in Man as a Model of Proliferative Inflammation....Pages 87-95
Aleutian Disease of Mink: A Systemic Immune Complex Vascular Disease of Viral Origin....Pages 96-105
Conditions of Vessel Wall Deposition of Immune Complexes in Immunologically Induced Vascular Diseases....Pages 106-117
Studies on the Vasculopathy of Rheumatoid Arthritis and Its Relation to “Systemic Rheumatoid Disease”....Pages 118-134
Discussion: Vascular Mechanism in Rheumatoid Inflammation....Pages 135-136
Enzyme Histochemical Demonstration of Certain Cell Populations in Synovium Using Plastic-Embedded Whole Rat Joints....Pages 137-143
Front Matter....Pages 145-145
Major Histocompatibility Complex Genes and the Genetic Regulation of the Immune Response: Relevance for Rheumatic Disease....Pages 147-155
Lymphocyte Populations and Subpopulations in Rheumatoid Arthritis....Pages 156-172
Cellular Immune Reactions in Erysipelas Polyarthritis in Pigs....Pages 173-185
Lymphocyte Reactivity in Patients with Rheumatoid Arthritis....Pages 186-198
Immune Complexes and Antiglobulins in Rheumatoid Arthritis....Pages 199-207
Front Matter....Pages 145-145
Complement Activation in Rheumatic Diseases: Mechanisms and Consequences....Pages 208-222
Discussion: Immune Reactions Involved in Rheumatoid Inflammation....Pages 223-224
Genetic Analysis of Rheumatoid Arthritis: Population and Family Studies....Pages 225-233
T-Cell-Mediated Immunopathology in Antigen-Induced Arthritis in Mice....Pages 234-238
Value of Different Immune Complex Assays in the Course of Rheumatoid Arthritis....Pages 239-243
A Platelet-Release-Inducing Immunoglobulin in Serum and Synovia from Patients with Rheumatoid Arthritis and Systemic Lupus Erythematosus....Pages 244-248
Front Matter....Pages 249-249
In Vitro Studies on the Metabolism of Human Connective Tissue Cells: Stimulation Factors in the Pathogenesis of Perpetuating Proliferation....Pages 251-261
Biomechanical Factors and Rheology in Inflammatory Joint Destruction....Pages 262-271
Biomechanical and Biochemical Problems in Diseases of Connective Tissue....Pages 272-284
Discussion: Biomechanical and Biochemical Aspects of Rheumatoid Inflammation....Pages 285-285
Glycosaminoglycans in the Discs of a Single Human Spine: The Distribution Pattern in Anulus Fibrosus and Nucleus Pulposus....Pages 286-289
Lysosomal Enzymes in Rheumatoid Inflammation: Biomechanical, Biochemical, and Morphological Investigations with Granulocyte Elastase as a Marker for Neutrophilic Polymorphonucleated Cells....Pages 290-296
New Methods in Synovial Fluid Rheology and Macromolecular Network Structure....Pages 297-303
Back Matter....Pages 305-309