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دانلود کتاب Apoptosis in neurobiology

دانلود کتاب آپوپتوز در نوروبیولوژی

Apoptosis in neurobiology

مشخصات کتاب

Apoptosis in neurobiology

ویرایش: 1 
نویسندگان: ,   
سری: CRC Press methods in the life sciences. Methods in neuroscience 
ISBN (شابک) : 0849333520, 9780849333521 
ناشر: CRC Press 
سال نشر: 1999 
تعداد صفحات: 271 
زبان: English 
فرمت فایل : PDF (درصورت درخواست کاربر به PDF، EPUB یا AZW3 تبدیل می شود) 
حجم فایل: 12 مگابایت 

قیمت کتاب (تومان) : 50,000



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در صورت تبدیل فایل کتاب Apoptosis in neurobiology به فرمت های PDF، EPUB، AZW3، MOBI و یا DJVU می توانید به پشتیبان اطلاع دهید تا فایل مورد نظر را تبدیل نمایند.

توجه داشته باشید کتاب آپوپتوز در نوروبیولوژی نسخه زبان اصلی می باشد و کتاب ترجمه شده به فارسی نمی باشد. وبسایت اینترنشنال لایبرری ارائه دهنده کتاب های زبان اصلی می باشد و هیچ گونه کتاب ترجمه شده یا نوشته شده به فارسی را ارائه نمی دهد.


توضیحاتی در مورد کتاب آپوپتوز در نوروبیولوژی

رشد سریع مطالعه مرگ سلولی تنظیم‌شده مبتنی بر مکانیسم آپوپتوز، نیاز فوری به مستندسازی قابل اعتماد از رویکردها و روش‌های مختلف مطالعه جنبه‌های مختلف این رشته را ایجاد کرده است. آپوپتوز در نوروبیولوژی منبع مهمی برای محققان در این مرز نوظهور مطالعه زیست پزشکی است. این جلد به عصب شناس ناآشنا امکان دسترسی فکری و عملی به مطالعه آپوپتوز را با توجه ویژه به سیستم عصبی می دهد. بخش اول بر روی رویکردهای مفهومی برای مطالعه آپوپتوز در نوروبیولوژی و اهمیت آن برای سیستم عصبی متمرکز است. بخش دوم یک رویکرد کاربرپسند به روش‌ها و تکنیک‌ها در مطالعه آپوپتوز که در نوروبیولوژی اعمال می‌شود، ارائه می‌کند


توضیحاتی درمورد کتاب به خارجی

The rapid growth of the study of apoptosis-mechanism-driven, regulated cell death-has created an urgent need for reliable documentation of the different approaches to and methods of studying the various aspects of the field. Apoptosis in Neurobiology is an important resource for researchers in this emerging frontier of biomedical study. This volume allows the uninitiated neuroscientist intellectual and practical access to the study of apoptosis, with special consideration to the nervous system. The first section concentrates on conceptual approaches to the study of apoptosis in neurobiology and its significance to the nervous system. The second section provides a user-friendly approach to methods and techniques in the study of apoptosis as applied to neurobiology



فهرست مطالب

Content: Machine generated contents note: SECTION 1 Financial, legal and contractual framework / Robert N. Hunter --
ch. 1 Highway Legislation: England and Wales / R. Pearson --
Introduction --
pt. I Highway authorities and agreements between authorities (sections 1-9) --
pt. II Trunk roads, classified roads, metropolitan roads, special roads (sections 10-23) --
pt. III Creation of highways (sections 24-35) --
pt. IV Maintenance of highways (sections 36-61) --
pt. V Improvements of highways (sections 62-105) --
pt. V A Environmental impact assessments (sections 105 A-D) --
pt. VI Construction of bridges over and tunnels under navigable waters and diversions etc. of watercourses (sections 106-111) --
pt. VII Provision of special facilities for highways (sections 112-115) --
pt. VII A Provision of amenities on certain highways --
pt. VIII Stopping up and diversion of a highway and stopping up of means of access to a highway (sections 116-129) --
pt. IX Lawful and unlawful interfaces with highways and streets (sections 130-185). Ch. 17 Traffic models for highway schemes / L.C. Darrall --
Introduction --
Multi-stage models --
Road traffic assignment models --
Microsimulation models --
Model calibration and validation --
References --
ch. 18 Forecasting future conditions / L.C. Darrall --
Introduction --
Principles of forecasting --
Future year forecasts --
Traffic forecasts for use in scheme appraisal --
References --
ch. 19 Scheme appraisal / J.H. Barlow --
Introduction --
National objectives for transport --
Local and regional objectives --
Improvements to identified problems --
Other issues --
Appraisal methodology --
The Brief --
Description of existing conditions --
Planning factors --
Description of scheme options --
Traffic assessment --
Cost estimates --
Safety assessment --
Economic assessment --
Environmental assessment --
Operational assessment --
Appraisal Summary Tables (ASTs) --
Implementation programme --
Conclusions --
References --
ch. 20 Public consultation / J.H. Barlow --
Introduction --
The Government\'s Code of Practice --
Types of public consultation --
The consultation process. Environmental impact assessment (EIA) --
Environmental assets --
evaluating what you have --
Assessment of environmental effects --
Design considerations --
Handover and long-term management --
References --
SECTION 5 Highway materials and recycling / Ian D. Walsh --
ch. 45 Highway materials: an introduction / I.D. Walsh --
Introduction --
Foundation layers --
Surface layers --
Conclusion --
References --
ch. 46 Unbound aggregates / J. McCulloch --
Introduction --
Terminology --
Production --
Materials and specifications --
Testing --
References --
ch. 47 Hydraulically bound mixtures for local roads / J. Kennedy --
Introduction --
HBM behaviour --
Pavement design and specification --
HBM for local authorities --
References --
ch. 48 Roller compacted concrete / J.P. Donegan --
Introduction --
Benefits of RCC --
Common applications of RCC --
RCC mix proportioning --
Mix design --
RCC constituents --
Quality control and test methods --
Construction methodology --
RCC properties --
Conclusions --
References. Ch. 49 Cold mix asphalt layers / I.D. Walsh --
Introduction --
Cold mix asphalt mix design for plant mixtures --
Cold mix asphalt mixing plant manufacture and installation --
Sustainability --
References --
ch. 50 Hot mix asphalt layers / C. Nicholls --
Introduction --
Mixture types --
Layers --
Sustainability --
Summary --
References --
ch. 51 Laying asphalts / R.N. Hunter --
Laying asphalt --
Production and transportation of asphalts --
Paver laid asphalt --
Surface regularity --
Laying chipped hot rolled asphalt surface courses --
Weather conditions --
Compaction of asphalts --
Ironwork --
Aftercare --
Quality assurance --
Epilogue --
References --
ch. 52 Small element paving: design and construction / A.J. Dowson --
Introduction --
Natural stone slabs, setts and concrete flags --
Lightly trafficked pavement design --
Heavy duty pavement design --
Ports and heavy duty pavement design --
Pavement overlay design --
Detailing and construction --
Permeable pavements --
Edge restraints --
References. Note continued: Site data collection --
Junction control methods --
Pedestrian crossings --
Road markings and traffic signs --
Vehicle movement restrictions --
Parking and loading restrictions --
References --
ch. 24 Capacity analysis / N. Robinson --
Introduction --
Junction types and their capacity --
Modelling the capacity of individual junctions --
Junction modelling software --
Networks --
Network modelling software --
Micro-simulation --
Micro-simulation software --
Conclusion --
References --
ch. 25 Highway layout and junction design / K. Buchholtz --
Introduction --
Design speed --
Stopping sight distance (SSD) --
Horizontal alignment --
Vertical alignment --
Minor access onto trunk roads --
Major/minor priority junctions (TA 42/95 and TD 41/95) --
Roundabouts --
Grade separation --
Signalised junctions and roundabouts --
Conclusion --
References --
ch. 26 Vehicle parking, waiting and loading / M. Slinn --
On-street parking --
Off-street parking --
Special users --
Parking management --
Credits --
References. Ch. 65 Levels of Service / J. Thorp --
Introduction --
Background --
Some definitions of Levels of Service --
Use of Levels of Service --
Developing Levels of Service --
Levels of Service recommendations --
Levels of Service statements --
Who are the customers and stakeholders and what are the authority objectives? --
Relationship between Levels of Service and authority objectives --
Levels of Service and engineering standards --
Suggested approach --
Conclusions --
Acknowledgements --
References --
Appendix A Code of Practice Themes --
ch. 66 Valuation of the assets / J. Thorp --
Introduction --
The importance of transport asset management --
The accounting approach --
Developing and using financial information --
Calculating depreciated replacement costs for a highway network --
Depreciation processing and reporting requirements (DRC) --
Developing inventory components and groupings --
References. Schedule 5 Distance limits from public road for purposes of compulsory acquisition --
Schedule 6 Special transitional provisions for trunk roads --
Schedule 7 Restricted roads --
Schedule 8 Penalties for offences --
Schedule 9 Minor and consequential amendments --
Schedule 10 Transitional provisions and savings --
Schedule 11 Repeals --
ch. 3 Highway Legislation: Northern Ireland / G. Anketell --
Introduction --
Primary legislation --
The Roads (Northern Ireland) Order 1993 --
pt. I Introduction --
pt. II Construction, maintenance and improvement of roads --
pt. III Special roads --
pt. IV Improvement and safety of roads --
pt. V Environmental assessment --
pt. VI Abandonments and stopping up of roads and private accesses --
pt. VII Lawful and unlawful interference with roads --
pt. VIII Road ferries --
pt. IX Powers of the Department in relation to land --
pt. X Miscellaneous and supplementary provisions --
The Schedules --
The Private Streets (Northern Ireland) Order 1980 (as amended by The Private Streets (Amendment) (Northern Ireland) Order 1992) --
pt. I Introduction. Note continued: Associated legislation --
References --
ch. 56 Maintenance policies / S. Child --
Introduction --
Policy framework --
The wider context --
Network management --
Duty or desire? --
Asset management --
Sustainability and highway maintenance --
Issues to consider --
Policy framework --
References --
Appendix A Document hierarchy --
Appendix B Policy content --
ch. 57 Maintenance types / R. Elphick --
Introduction --
Cyclic maintenance --
Planned maintenance --
Materials --
Design options --
Reactive maintenance --
Reference --
ch. 58 The maintenance organisation / P. Jameson --
The basic shape of a maintenance organisation --
Direct labour or contract --
Contract types --
Relationship between workforce size and winter maintenance --
Inspection regimes --
Training and development --
References. Ch. 27 Modern traffic management / G. Higgs --
Approach --
Techniques --
Application --
Design considerations --
References --
ch. 28 Assisting public transport / P. Matthews --
Introduction --
Road-based public transport --
Traffic management measures --
Parking management measures --
Bus lanes: with flow --
Bus lanes: contraflow --
Bus-only streets and bus-ways --
Traffic signal control --
Bus stop infrastructure --
Bus priority: consideration of other road users --
Evaluation of bus priority measures --
References --
ch. 29 Road safety engineering / P. Matthews --
Introduction --
Accidents --
Causes of crashes --
Contribution and consequences of speeding --
Types of crashes (accidents) --
Accident data collection --
Road safety plans --
Road safety engineering --
Accident remedial schemes: process --
Detailed site analysis --
Accident remedial measures --
Measuring the effectiveness of accident remedial schemes --
Road safety audits --
References --
ch. 30 Intelligent transport systems / A. Carter --
Introduction --
ITS and the ICE manual of highway design and management. Ch. 34 Drainage design / S. Young --
Introduction --
Elements of a road drainage system --
Initial design stages --
Network analysis --
Design of pollution control and flood prevention measures --
Design of other elements --
Design deliverables --
DMRB advice and guidelines --
References --
ch. 35 Private developer projects / T. Hydes --
Introduction --
The Highways Act and Approvals --
Planning policy --
Car parking --
Shared spaces --
User requirements --
Highway design (or Design) --
References --
ch. 36 Pavement design (highways) / I.D. Walsh --
Introduction --
Foundation support --
Traffic loading --
Structural layer design --
flexible pavements --
Structural layer design --
composite pavements --
Design for maintenance --
Selection of materials types --
References --
ch. 37 Pavement design (highways rigid) / G. Griffiths --
Introduction --
Typical concrete pavement types --
Detailing concrete pavements --
Fibre-reinforced concrete --
The surface finish --
Slip membranes --
Slip-road detailing --
Transition slabs. Ch. 53 Surface treatments for highways / I.D. Walsh --
Introduction --
Bitumen binders --
Surface dressing --
Slurry surfacing/microsurfacing (sometimes referred to as microasphalt) --
High friction surfacing (HFS) --
Patching --
Retexturing --
Plant --
Retread/repave --
Stress absorbing membrane interlay (SAMI) --
Imprinted surfaces --
Surface preservation systems --
The highway engineers toolbox --
a concept --
Guidance on using the highway engineer\'s toolbox --
References --
ch. 54 Road markings / K. Grant --
Introduction --
The materials --
Application --
Performance requirements --
Testing and inspection methods --
Quality control --
Quality assurance --
References --
SECTION 6 Maintenance planning and techniques / Paul Jameson --
ch. 55 Introduction and scope / R. Elphick --
Introduction --
Factors affecting maintenance --
Balancing maintenance need and investment --
Maintenance funding --
Maintenance asset management systems --
Condition assessment. Planning the consultation --
Targeting the audience --
Engaging consultees --
the exhibition --
Engaging consultees --
the questionnaire --
Engaging consultees --
focus groups --
The Public Consultation Report --
Feedback --
The outcome --
influencing decision-makers --
References --
SECTION 3 Traffic engineering / Paul Matthews --
ch. 21 Introduction, history, definition / P. Matthews --
The history of traffic and its management --
ch. 22 Traffic engineering legislation / P. Matthews --
Introduction --
Current legislation --
References --
ch. 23 Traditional traffic management / C. Whitehead --
Introduction. Travel and traveller information --
Network management --
urban --
Junction and network performance --
Network management --
interurban --
Road user charging, congestion charging and electronic toll systems --
Road safety --
Driver assistance --
Public transport travel information --
Future ITS --
European ITS Directive --
References --
SECTION 4 Highway design principles and practice / Ian D. Walsh --
ch. 31 Highway design principles and practice: an introduction / I.D. Walsh --
Background --
The design process --
Conclusions --
References --
ch. 32 Site investigation and foundation design / I.R. Payne --
Introduction --
Stages of site investigation --
Groundwater and drainage --
Slope stability --
Embankment fills --
Road pavement subgrade --
Ground movement and subsidence --
Foundation design for structures --
References --
ch. 33 Geometric design / M. Westlake --
Introduction --
Basic philosophy: the information --
Geometry issues --
Junction design --
Highway features --
A practical design --
References. Ch. 59 Politics and public / B. Thompson --
Introduction --
The political scene --
Working with the public --
Dealing with the media --
References --
ch. 60 The involvement and impact of the utilities / R. Elphick --
Introduction --
Legislation --
The coordination process --
Noticing rules --
Work categories --
Electronic transfer of notices (EToN) --
Permits --
Restrictions following work activities --
Inspections --
Penalties --
Industry organisations --
The impact of reinstatements on highway pavements --
The research programme --
Charging structures --
Determining the cost of premature maintenance --
Creating a charge structure --
References --
ch. 61 Winter service and other weather emergencies / S. Child --
Introduction --
Statutory basis --
Policy --
Winter service objectives --
Winter Service Plan --
Network hierarchy and route optimisation --
Salt bins --
Weather prediction and information. The applicable law of the contract --
Selection of the conditions of contract In practice --
The ICE conditions of contract, 7th edition --
The Engineering and Construction Contract 3rd Edition (NEC3) --
References --
ch. 10 National specification and design documents / R.N. Hunter --
Introduction --
Design manual for roads and bridges --
Interim Advice Notes --
Manual of contract documents for highway works --
References --
Annex A Design Manual for Roads and Bridges --
Annex B Manual of Contract Documents for Highway Works --
ch. 11 Local specifications and design documents / I.D. Walsh --
Introduction --
Local specifications --
Local modifications to the specification for highway works --
Local design documents --
References --
ch. 12 European Standards for products / I.D. Walsh --
Introduction --
Mandates and essential requirements --
The contents of a European Standard --
Durability --
National guidance --
How Standards are produced --
Quality assurance under a European Standard --
Quality assurance and quality --
References. Highways Agency schemes funding --
Local authority schemes funding --
Developer funding --
Community infrastructure levy (CIL) --
Direct local authority funding --
Practical funding considerations for promoters --
References --
ch. 7 Highway capital maintenance / M. Sutch --
Introduction --
Block allocations --
Highway capital maintenance funding --
2010/11 allocations levels --
Future funding levels --
References --
ch. 8 Revenue funding for maintenance activities / T. Oakley --
Background to revenue funding --
The formula grant --
Calculation of the highway maintenance element of the formula grant --
Calculation of the capital financing element of the formula grant --
Sources of further information --
ch. 9 Forms of contract for highway construction projects / M. O\'Reilly --
Introduction --
Introduction to highway construction contracts --
The use and importance of contracts in construction --
Types and features of highway contracts --
Statutory controls and impact --
Tendering practice --
Documents forming part of the construction contract. pt. X New streets (sections 186-202) --
pt. XI Making up of private streets (sections 203-237) --
pt. XII Acquisition, vesting and transfer of land etc. (sections 238-271) --
pt. XIII Financial provision (sections 272-281) --
pt. XIV Miscellaneous and supplementary provisions (sections 282-345) --
References --
ch. 2 Highway Legislation: Scotland / J.R. Edgar --
Introduction --
pt. I Public roads --
pt. II Private roads --
pt. III New roads --
pt. IV Improvements and maintenance --
pt. V Roads and building control --
pt. VI Access and stopping up --
pt. VII Bridges, tunnels and diversion of water --
pt. VIII Interference and damage --
pt. IX Acquisition, transfer, vesting and compensation --
pt. X Miscellaneous --
pt. XI Offences --
pt. XII Statutory undertakers --
pt. XIII General --
Schedule 1 Procedures for making or confirming certain orders and schemes --
Schedule 2 Validity and date of operation of certain orders and schemes --
Schedule 3 Classes of traffic for purposes of special roads --
Schedule 4 Procedure for determination by roads authority of certain questions in connection with cattle-grids. Ch. 41 Surface characteristics (noise) / I.D. Walsh --
Introduction --
Measurement of noise --
Traffic noise generation --
Noise reduction --
Traffic noise mitigation and compensation --
References --
ch. 42 Skid resistance / D. Woodward --
Introduction --
Simple definitions relating to skid resistance --
Specification of skid resistance in the UK --
Measurement of skid resistance --
Skid resistance measurement and device operation --
Skid resistance, water and surface texture --
Skid resistance measurement devices used in the UK --
The Wehner-Schulze Test --
Skid resistance and type of aggregate --
Future trends --
Conclusions --
References --
ch. 43 Sustainability / T. Parry --
Introduction --
Resource use, recycling and waste --
Public transport, walking and cycling --
Adaptation to climate change --
Assessment systems --
Corporate responsibility --
References --
ch. 44 Environmental considerations / M. Glanville --
Introduction/key background information on topic. pt. II Laying out and construction of streets --
pt. III Adoption of private streets as public roads --
pt. IV Making up of private streets --
pt. V Prior provision for expenses of street works in private streets --
pt. VI Miscellaneous --
References --
ch. 4 Public procurement / J. McRorie --
Introduction --
Background and legal framework --
When do the regulations apply? --
What must be done to comply with the rules: the procurement process --
What are the consequences of a failure to comply with the procurement rules? --
References --
ch. 5 Funding the Highways Agency: estimates, funding, monitoring / P. Stiverson --
Introduction --
Central government organisation funding --
Government agencies --
Aim and objectives of the Highways Agency --
The Highways Agency: roles, responsibilities and governance --
The Highways Agency: business planning framework business plans --
The Highways Agency: financial and investment arrangements --
References --
ch. 6 Major highway scheme finance / J. Farmer --
Introduction --
Basic accounting definitions. Pavement anchorages --
Joint design and detailing --
Design methods --
Deterioration mechanisms and site construction problems --
Construction methods --
Concluding remarks --
Acknowledgements --
References --
ch. 38 Pavement design (ancillary usage) / I.D. Walsh --
Industrial pavement design --
Car parks and light access way design --
Sports surfaces --
Playgrounds --
Footways and cycleways --
Public footpaths and other public rights of way (PROW) --
Farm roads --
References --
ch. 39 Analytical pavement design / B. Al Hakim --
Introduction --
Development of pavement design --
Design development in the UK --
The AASHTO design method --
Analytical pavement design principles --
Pavement modelling --
Analytical evaluation of existing pavements --
Summary --
References --
ch. 40 Unsealed highway construction / A. Dawson --
Introduction --
Materials --
Performance and failure --
Design --
Construction --
Maintenance --
Environmental aspects --
In-situ testing --
References. SECTION 2 Transport planning / Leslie C. Darrall --
ch. 13 Introduction to policy and practice / L.C. Darrall --
Introduction --
The Strategic Planning Framework --
Roles and responsibilities --
Policies, plans and programmes --
Appraisal of transport plans --
Highway scheme planning and implementation --
Impending changes to the planning system in England --
References --
ch. 14 Existing conditions and data / M.J. Yeadon --
Introduction --
Existing conditions and data --
Types of survey --
Developing the scope of surveys --
Sources of existing information --
Bespoke surveys --
Traffic-related surveys for economic appraisal --
Traffic-related surveys for environmental appraisal --
Summary --
References --
ch. 15 Characteristics of transport and travel / M.J. Yeadon --
Introduction --
General trends in transport and travel --
Private car travel --
Freight traffic --
Road traffic safety --
Transport and travel choices --
Summary --
References --
ch. 16 Estimating transport demand / L.C. Darrall --
Introduction --
Choice of modelling approach --
Demand models --
Types of models --
References. Ch. 67 Lifecycle planning / J. Thorp --
Introduction --
The lifecycle process --
Objectives and policies --
Inventory and condition data --
Cost of maintaining each group of assets --
Performance gaps --
Demands and risks --
Appendix A Carriageway lifecycle plan --
Acknowledgements --
References --
ch. 68 Asset management strategy and risk management / J. Thorp --
Asset management strategy --
Investment strategy --
Risk assessment --
Introduction to the evaluation of risk in asset management --
Existing guidance --
Simple steps to get started in risk management --
Continuing improvement in the future --
Appendix A Definitions --
Appendix B Background information --
Acknowledgements --
References --
ch. 69 Developments and conclusions / J. Thorp --
UK Pavement Management System --
Prioritisation of highway works and deterioration models --
Working the highway data --
Taking stock and annual reviews --
Conclusion --
References.




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