Advances in Prostaglandin, Leukotriene, and other Bioactive Lipid Research: Basic Science and Clinical Applications

Front Matter....Pages i-xxvi
Leukotrienes in Asthma....Pages 1-5
Leukotriene Receptors: State of the Art....Pages 7-10
LTC 4 Production by Eosinophils in Asthmatic Subjects with Alternative Forms of Alox-5 Core Promoter....Pages 11-14
IL-4-Induced Lipid Mediators Class Switching in Human Normal Mononuclear Phagocytes....Pages 15-18
Lipoxins and Aspirin-Triggered Lipoxins in Airway Responses....Pages 19-23
Potential Role of Cysteinyl Leukotrienes in Trafficking and Survival of Hematopoietic Progenitor Cells....Pages 25-28
Covalent Binding of Leukotriene A 4 to Nucleosides, Nucleotides, and Nucleic Acids....Pages 29-33
Firm Adhesion of Neutrophils to Cerebral Vascular Endothelium “In Vivo”: A Role for Cysleukotrienes....Pages 35-38
The CYP P450 Arachidonate Monooxygenases: Enzymatic Relays for the Control of Kidney Function and Blood Pressure....Pages 39-46
Cytochrome P450-Derived Eicosanoids are Mediators of Ocular Surface Inflammation....Pages 47-54
Regulation of Renal Microvascular 20- Hydroxyeicosatetraenoic Acid (20-Hete) Levels....Pages 55-58
Cyclooxygenase Activity is Regulated by the Heme Oxygenase System in Microvessel Endothelial Cells....Pages 59-66
Cytochrome P450 Arachidonic Acid Metabolites Modulate Renal Tubular Function....Pages 67-69
Thromboxane-Induced Erk Phosphorylation in Human Aortic Smooth Muscle Cells....Pages 71-73
Arachidonic Acid Inhibits Cysteinyl-Leukotriene Receptor Activation in Human Pulmonary Vessels....Pages 75-79
Cytosolic Phospholipase A 2α in Mouse Platelets....Pages 81-86
Cellular Arachidonate-Releasing Functions of Various Phospholipase A 2 s....Pages 87-92
Biological Functions of Group X Secretory PLA 2 ....Pages 93-96
Protection of Cell Membrane from Exogenous PLA 2 and Related Inflammatory Stimuli by Membrane-Anchored Lipid Conjugates....Pages 97-101
Regulatory Functions of Prostaglandin E 2 Synthases....Pages 103-106
A Novel Type of Membrane-Associated Prostaglandin E Synthase....Pages 107-111
Expression, Purification and Characterization of Recombinant Human Microsomal PGE 2 Synthase-1....Pages 113-116
Formation of Prostaglandin E 2 , Leukotriene B 4 And 8-Isoprostane in Alveolar Macrophages by Ultrafine Particles of Elemental Carbon....Pages 117-120
Effects of PGF 2α Analogues in Experimental Morphine-Induced Pharmacodependence....Pages 121-124
Inhibition of Prostaglandin H 2 Synthases by Salicylate is Dependent on the Oxidative State of the Enzymes....Pages 125-128
5-Lipoxygenase Activation by Mapkapk-2 and Erks....Pages 129-132
Renal Effects of Selective Cyclooxygenase Inhibition in Experimental Liver Disease....Pages 133-136
Variable Antipyretic Effect of SC-58236, a Selective Cyclooxygenase (COX)-2 Inhibitor, in Rats....Pages 137-140
Induction of Cyclooxygenase-2 Expression by Fluid Shear Stress in Vascular Endothelial Cells....Pages 141-144
Induction of COX-2 Expression by the Endocannabinoid Derivative R(+)-Methanandamide....Pages 145-152
Specific Gene Expression of Isoforms in Cyclooxygenase Pathway to Generate PGJ 2 Derivatives during the Differentiation of 3T3-L1 Adipocytes....Pages 153-156
Tristetrapolin Binds to the COX-2 mRNA 3’ Untranslated Region in Cancer Cells....Pages 157-160
Platelet Activating Factor Receptors....Pages 161-164
Splicing Mutation of the Prostacyclin Synthase Gene in a Family Associated with Hypertension....Pages 165-168
DNA Methylation Regulates 5-Lipoxygenase Promoter Activity....Pages 169-172
Isomerization and Nitro-Oxidation of Arachidonic Acid by NO 2 ....Pages 173-176
Prostaglandin F 2α Protected Cultured Madin-Darby Canine Kidney Cells from the Development of Apoptosis Induced by 12- O -Tetradecanoyl Phorbol-β- Acetate and Stimulated Synergistically with Nordihydroguaiaretic Acid....Pages 177-180
LDL Receptor-Related Protein Plays An Essential Role In 12/15-Lipoxygenase-Mediated LDL Oxidation By Macrophages....Pages 181-184
Effects of In Vitro Exposure to Carbon Dioxide on the Expression of Apoptosis-Associated Genes in Human Peritoneal Fibroblasts....Pages 185-188
Identification, Characterization, and Properties of a Class Alpha Microsomal Glutathione S- Transferase....Pages 189-192
Cyclooxygenase (COX) Function in the Ductus Arteriosus: Another Look....Pages 193-196
Evidence for Enhanced Oxidative Stress in Coronary Heart Disease and Chronic Heart Failure....Pages 197-200
The Leukotriene Receptor CYSLT 1 And 5- Lipoxygenase Are Upregulated In Colon Cancer....Pages 201-204
Increased Expression of 5-Lipoxygenase In Glioblastoma Multiforme....Pages 205-208
Variable Influence of Statins on Isoprostanes in Hyperlipidemia....Pages 209-212
Increased Isoprostanes in Children of Smoking Parents....Pages 213-215
The Dinor Isoprostane Pathway in Plants....Pages 217-220
Back Matter....Pages 221-226