Advances in Bioprocess Engineering

Front Matter....Pages i-xvi
Bioreactor Engineering....Pages 1-11
Design and Scale-up of External-Loop Airlift Bioreactor....Pages 13-19
Engineering a Successful Scale-Up of a Process to Produce a rDNA Product....Pages 21-23
Slurry Bioreactor Design for Shear-Sensitive Mycoprotein Production....Pages 25-28
Strategies in the Design of a Penicillin Acylase Process....Pages 29-40
Scaling-Up of a Lipase Fermentation Process: A Practical Approach....Pages 41-46
Optimum Design of a Continuous Fermentation Unit of an Industrial Plant for Alcohol Production....Pages 47-52
Scale-up....Pages 53-65
High Cell Density Yeast Production: Process Synthesis and Scale-Up....Pages 67-74
Continuous Flow Cell-Recycle Fermentation of Biomass Hydrolysates....Pages 75-80
Physiological and Technico-Engineering Aspects of Lignocellulose Solid-State Fermentation with Filamentous Fungi....Pages 81-86
Growth of Candida utilis on Amberlite with Glucose and Ethanol as Sole Carbon Sources....Pages 87-93
Scaling-up Aerobic Fermentation which Produce Non-Newtonian, Viscoelastic Broths....Pages 95-101
Plant Cells as Chemical Factories: Control and Recovery of Valuable Products....Pages 103-107
Optimization of Fed-Batch Mammalian Cell Culture Processes....Pages 109-113
A Fluidized Bed Reactor for the Cultivation of Animal Cells....Pages 115-121
Influence of Time and Multiplicity of Infection on the Batch Production of Anticarsia gemmatalis Nuclear Polyhedrosis Virus in Lepidopteran Insect Cell Cultures....Pages 123-128
Design of Tubular Microporous Membrane Aerated Bioreactors for Plant Cell Suspension Culture....Pages 129-132
Optimization and Scale-Up of High Density Cell Culture Bioreactors....Pages 133-139
Recent Studies on Stirred Bioreactors at the SERC Centre for Biochemical Engineering at Birmingham....Pages 141-147
Role of Turbulence in Fermentations....Pages 149-156
Power Input and Oxygen Transfer in Fed-Batch Penicillin Production Process....Pages 157-162
The Examination of Bioreactor Heterogeneity with Rheological Different Fermentation Broths....Pages 163-170
The Influence of Cell Concentration and Morphology on the Yielding Behavior of Filamentous Fermentation Broths....Pages 171-182
A New Approach for Modelling the Kinetics of Mycelial Cultures....Pages 183-189
On-Line Estimation of Yeast Growth Rate Using Morphological Data from Image Analysis....Pages 191-195
Growth and Protein Formation of Recombinant Aspergillus : Utility of Morphological Characterization by Image Analysis....Pages 197-202
Inducing Controlled Growth of Penicillium chrysogenum in Pelletized Form....Pages 203-206
Structured Modelling of Bioreactors....Pages 207-215
Measurement and Modelling of Oxygen Transport into Biotechnical Immobilisates for Cell Entrapment....Pages 217-220
Diffusion of Phosphate Ion in Xanthan Gum Solutions....Pages 221-225
Modeling Protease Production by Immobilised Serratia marcescens ....Pages 227-232
A Mathematical Model for a Fermentation Process Carried Out in a Fluidized Bed Reactor....Pages 233-239
Modelling the Growth of Acidothermus cellulolyticus ....Pages 241-245
Bioreactor Coupled On-Line Measurements....Pages 247-253
An Experimental Guide to the Relevant Aeration Rates in Microaerobic Bioprocesses....Pages 255-265
Model Aided Multiple Correlation Analysis between Preculture and Main Fed Batch Culture....Pages 267-273
Identification Techniques for a Recombinant Fed-Batch Fermentation for Ethanol Production....Pages 275-282
Computer Controlled Enzymatic Reactor....Pages 283-287
Pressure Drop as a Method to Evaluate Mold Growth in Solid State Fermentors....Pages 289-294
Computer-Aided Design of Integrated Biochemical Process....Pages 295-303
A Strategy for the pH Control in Acidic Wastewaters....Pages 305-312
Modeling and Control Strategies for the Transformation of D-Sorbitol to L-Sorbose on a Laboratory Bioreactor....Pages 313-320
The Control Problem for Protein Separation by the Continuous Affinity Recycling Extraction Process....Pages 321-328
Biodegradation of PCP in Contaminated Soil and in the Aqueous Phase....Pages 329-335
Biodenitrification Studies with a Bioreactor Operating in a Periodic Mode....Pages 337-344
Dynamic Behavior of Activated-Sludge in Exponentially Fed-Batch Cultures Subjected to Step Perturbations....Pages 345-353
Expansion Characteristics of Tapered Fluidized-Bed Bioreactors....Pages 355-363
High-Rate Biofilm Fluidized Bed Reactors for Specialized Wastewater Treatment....Pages 365-378
The Effect of Concentration and Hydraulic Shock Loads on the Performance of a Two-Stage High-Rate Anaerobic Wastewater Treatment System: Prediction and Validation....Pages 379-384
Investigation of Kinetic and Microbiological Features of UASB-Reactor Performance Under Various Organic Loading Rates....Pages 385-390
Reduction of Antiphysiological Compounds of Coffee Pulp Through Solid State Fungal Fermentation....Pages 391-396
Biological Removal of Hydrophobic Solvent Vapors from Airstreams....Pages 397-404
Toluene Removal from Air Stream by Biofiltration....Pages 405-411
Metabolic Engineering of Cephalosporin Biosynthesis in Streptomyces clavuligerus ....Pages 413-415
High Production of Lactic Acid from Metabolically Engineered Saccharomyces cerevisiae ....Pages 417-423
Some Aspects of Gibberella fujikuroi Culture Concerning Gibberellic Acid Production....Pages 425-430
Continuous Culture to Produce Recombinant β-Galactosidase in Bacillus subtilis ....Pages 431-435
Rapid Ethanol Production from Sucrose Using Zymomonas mobilis ....Pages 437-440
Improved Production of Proteases by Brevibacterium linens in Submerged Culture....Pages 441-445
Production of K1 (Streptokinase) Using Batch and Fed-Batch Culture of Recombinant E. coli ....Pages 447-453
Microbial Protein Production by Submerged Fermentation of Mixed Cellulolytic Cultures....Pages 455-460
Chitin as a Matrix for Enzyme Immobilization....Pages 461-466
Enzyme Reactor Performance Under Thermal Inactivation....Pages 467-472
Process Strategies in Enzymatic Racemate Resolution....Pages 473-480
Design of Reaction Medium for Nonaqueous Biocatalysis: Analysis on Enzyme Hydration and Catalytic Activity in Organic Solvent....Pages 481-484
New Approaches to the Enzymatic Production of Oligopeptides: Synthesis of the “Delicious Peptide” and its Fragments....Pages 485-488
 Aspergillus sp . 2M1 Xylanase: Production, Characterization and Application in the Pulp and Paper Industry....Pages 489-494
Optimization of Cell Harvesting and Assay Procedures for Reductive Biotransformations in Obligate Anaerobes....Pages 495-499
A Scalable Method for the Purification of Recombinant Human Protein C from the Milk of Transgenic Swine....Pages 501-507
A Laboratory Study on the Behavior of Thiobacillus ferrooxidans during Pyrite Bioleaching in Percolation Columns....Pages 509-517
Purification of G6PDH from Unclarified Yeast Cell Homogenate Using Expanded Bed Adsorption (EBA) with STREAMLINE TM Red H-E7B....Pages 519-525
Purification of Recombinant Hepatitis B Surface Antigen (rec-HBsAg) from P. pastoris : A Process Development Study....Pages 527-534
Evaluation of Affinity Chromatographic Methods in the Purification of Recombinant Streptokinase....Pages 535-540
Back Matter....Pages 541-541