Adrenergic Mechanisms in Myocardial Ischemia

Front Matter....Pages i-ix
Front Matter....Pages 1-1
Topical Organization of the Cardiac Sympathetic Nervous System....Pages 3-8
Cardiac Sympathetic Activity in Myocardial Ischemia: Release and Effects of Noradrenaline....Pages 9-30
Modulation of α-Adrenergic Receptors and their Intracellular Coupling in the Ischemic Heart....Pages 31-45
β-Adrenergic Receptors and the G s Protein in Myocardial Ischemia and Injury....Pages 47-56
β- and α-Adrenoceptor-Agonists and -Antagonists in Chronic Heart Failure....Pages 57-66
Supersensitivity of the Adenylyl Cyclase System in Acute Myocardial Ischemia: Evaluation of Three Independent Mechanisms....Pages 67-78
Front Matter....Pages 79-79
α-Adrenoceptor Subtypes in the Coronary Circulation....Pages 81-95
α- and β-Adrenergic Control of Large Coronary Arteries in Conscious Calves....Pages 97-109
Adrenergic Vasomotion in the Coronary Microcirculation....Pages 111-120
Neurohumoral Regulation of Coronary Collateral Vasomotor Tone....Pages 121-129
α-Adrenergic Regulation of Myocardial Performance in the Exercising Dog: Evidence for Both Presynaptic α 1 - and α 2 -Adrenoceptors....Pages 131-141
Front Matter....Pages 143-143
Transmural Steal with Isoproterenol and Exercise in Poststenotic Myocardium....Pages 145-155
Mechanisms of Benefit in the Ischemic Myocardium due to Heart Rate Reduction....Pages 157-166
Adrenergic Control of Transmural Coronary Blood Flow....Pages 167-176
α 1 -Adrenergic Coronary Constriction during Exercise and Ischemia....Pages 177-192
Contribution of Postsynaptic α 2 -Adrenoceptors to Reflex Sympathetic Constriction of Stenotic Coronary Vessels....Pages 193-206
α 2 -Adrenergic Coronary Constriction in Ischemic Myocardium during Exercise....Pages 207-217
Prevention of α-Adrenergic Coronary Constriction by Calcium-Antagonists....Pages 219-228
Effects of Selective Cardiac Denervation on Collateral Blood Flow after Coronary Artery Occlusion in Conscious Dogs....Pages 229-239
Front Matter....Pages 241-241
Cardiocardiac Excitatory Reflexes during Myocardial Ischemia....Pages 243-252
Front Matter....Pages 241-241
Pain and Myocardial Ischemia: the Role of Sympathetic Activation....Pages 253-266
No Impairment of Sympathetic Neurotransmission in Stunned Myocardium....Pages 267-280
Front Matter....Pages 281-281
Does Noradrenaline Influence the Extracellular Accumulation of Potassium, Sodium, Calcium, and Hydrogen Ions ([K + ] e , [Na + ] e , [Ca 2+ ] e , [H + ] e ) during Global Ischemia in Isolated Rat Hearts?....Pages 283-292
Effects of β-Blockade on the Incidence of Ventricular Tachyarrhythmias during Acute Myocardial Ischemia: Experimental Findings and Clinical Implications....Pages 293-303
Sympathetic — Parasympathetic Interaction and Sudden Death....Pages 305-321
Front Matter....Pages 323-323
Heart Rate and β -Adrenergic Mechanisms in Acute Myocardial Infarction....Pages 325-333
Coronary Vasomotor Tone in Large Epicardial Coronary Arteries with Special Emphasis on β -Adrenergic Vasomotion, Effects of β -Blockade....Pages 335-346
The Poststenotic Vessel Segment during Dynamic Exercise: Effect of Oral Isosorbide-dinitrate....Pages 347-357
α-Adrenergic Coronary Constriction in Effort Angina....Pages 359-369
Back Matter....Pages 371-376