Adjuvant Therapy of Primary Breast Cancer VI

Front Matter....Pages I-XVI
Front Matter....Pages 1-1
Diet and Mammary Gland Carcinogenesis....Pages 3-10
Prevention of Breast Cancer: Focus on Chemoprevention....Pages 11-21
Estrogen/Hormone Replacement Therapy and the Etiology of Breast Cancer....Pages 22-31
Front Matter....Pages 33-33
Experimental Pathology and Breast Cancer Genetics: New Technologies....Pages 35-48
Update on Breast Cancer Susceptibility Genes....Pages 49-59
Front Matter....Pages 61-61
IGF-I Physiology and Breast Cancer....Pages 63-70
Determination of Clinical Utility of Tumor Markers: A Tumor Marker Utility Grading System....Pages 71-85
How Can Prognostic and Predictive Factors in Breast Cancer Be Used in a Practical Way Today?....Pages 86-93
Strategies for the Development of Vaccines to Treat Breast Cancer....Pages 94-102
Front Matter....Pages 103-103
Hypothesis and Practice: Are There Several Types of Treatment for Ductal Carcinoma In Situ of the Breast?....Pages 105-122
Ductal Carcinoma In Situ of the Breast: Histological Classification and Genetic Alterations....Pages 123-134
Trials of Treatment for Non-invasive Breast Cancer....Pages 135-142
Summary....Pages 143-146
Front Matter....Pages 147-147
The Axilla: To Clear or Not to Clear? That Is the Question!....Pages 149-160
Axillary Clearance in Operable Breast Cancer: Still a Necessity?....Pages 161-169
Sentinel Lymphadenectomy: A Safe Answer to Less Axillary Surgery?....Pages 170-179
Endoscopic Surgery to the Axilla — A Substitute for Conventional Axillary Clearance?....Pages 180-189
Front Matter....Pages 191-191
Surgical Considerations in Preoperative Chemotherapy of Breast Cancer....Pages 193-201
Integration of Plastic Surgery in the Course of Breast-Conserving Surgery for Cancer to Improve Cosmetic Results and Radicality of Tumor Excision....Pages 202-211
Summary....Pages 212-214
Front Matter....Pages 215-215
Is Primary Chemotherapy Useful for All Patients with Primary Invasive Breast Cancer?....Pages 217-226
The Primary Use of Endocrine Therapies....Pages 227-244
Front Matter....Pages 245-245
Why and How to Combine Chemotherapy and Radiation Therapy in Breast Cancer Patients....Pages 247-254
Novel Approaches Using Radiation Therapies....Pages 255-264
Molecular Biology of the Estrogen Receptor Aids in the Understanding of Tamoxifen Resistance and Breast Cancer Prevention with Raloxifene....Pages 265-276
Aromatase Inhibitors and Their Use in the Adjuvant Setting....Pages 277-284
GnRH Analogues and Ovarian Ablation: Their Integration in the Adjuvant Strategy....Pages 285-297
Summary....Pages 298-301
Front Matter....Pages 303-303
Putting the Taxanes to Work: Unanswered Questions....Pages 305-313
Putting Taxanes to Work in Operable Breast Cancer: A Search for Selective Indications from Empirical Studies....Pages 314-322
Continuous Infusional Chemotherapy for Early Breast Cancer: The Royal Marsden Hospital Experience....Pages 323-327
Tailored Chemotherapy to Equal Toxicity: Is It Possible?....Pages 328-340
Anti-angiogenesis Therapy and Strategies for Integrating It with Adjuvant Therapy....Pages 341-352
Front Matter....Pages 353-353
New Developments in High-Dose Chemotherapy for Breast Cancer....Pages 355-367
Summary....Pages 368-370
Front Matter....Pages 371-371
Quality of Life Assessment in the Adjuvant Setting: Is It Relevant?....Pages 373-389
Quality of Life Assessment in the International Breast Cancer Study Group: Past, Present, and Future....Pages 390-395
Impact of Different Adjuvant Therapy Strategies on Quality of Life in Breast Cancer Survivors....Pages 396-411
Summary....Pages 412-414
Front Matter....Pages 415-415
North American Adjuvant Breast Cancer Trials....Pages 417-428
Front Matter....Pages 415-415
International Breast Cancer Study Group Trials....Pages 429-440
Nordic Trials of Adjuvant Therapy in Primary Breast Cancer....Pages 441-446
The EORTC-Breast Cancer Cooperative Group Clinical Research Programme in Early Breast Cancer....Pages 447-452
Italian Breast Cancer Adjuvant Chemo-hormone Therapy Cooperative Group Trials....Pages 453-470
Current Trials of the German Adjuvant Breast Cancer Group (GABG)....Pages 471-478
Front Matter....Pages 479-479
International Consensus Panel on the Treatment of Primary Breast Cancer V: Update 1998....Pages 481-497
Back Matter....Pages 499-508