50 Studies Every Ophthalmologist Should Know

cover
Half Title
Serious
50 Studies Every Ophthalmologist Should Know
Copyright
Contents
Preface xi
1. Effectiveness of Histocompatibility Matching in High- Risk Corneal Transplantation: Collaborative Cornea Transplant Studies (CCTS) 1
2. Topical Corticosteroids for Herpes Simplex Stromal Keratitis: The Herpetic Eye Disease Study (HEDS) 9
3. Topical Corticosteroids for Bacterial Keratitis: The Steroids for Corneal Ulcers Trial (SCUT) 15
4. Topical Natamycin Versus Voriconazole for Fungal Corneal Ulcer: Mycotic Ulcer Treatment Trial (MUTT) 21
5. Prevalence of Age- Related Lens Opacities in a Population: The Beaver Dam Eye Study 27
6. Risk Factors for Cataract: The Lens Opacities Case- Control Study 33
7. High- Dose Supplementation with Vitamins C and E and Beta Carotene for Age- Related Cataract and Vision Loss: The Age- Related Eye Disease Study (AREDS) 39
8. Routine Preoperative Medical Testing Before Cataract Surgery: Study of Medical Testing for Cataract Surgery 45
9. Prophylaxis of Postoperative Endophthalmitis Following Cataract Surgery: ESCRS Endophthalmitis Study 51
10. The Relationship Between Optic Disc Area and Open- Angle Glaucoma: The Baltimore Eye Survey 57
11. Is Argon Laser Trabeculoplasty Equivalent to Topical Medication as an Initial Treatment for Primary Open- Angle Glaucoma? The Glaucoma Laser Trial (GLT) 61
12. Intraocular Pressure Reduction in the Treatment of Normal- Tension Glaucoma: Collaborative Normal- Tension Glaucoma Study (CNTGS) 67
13. The Relationship Between Control of Intraocular Pressure After Surgical Intervention for Glaucoma and Visual Field Deterioration: The Advanced Glaucoma Intervention Study (AGIS) 73
14. Reduction of Intraocular Pressure and Glaucoma Progression: Early Manifest Glaucoma Trial (EMGT) 79
15. Topical Ocular Hypotensive Medication to Delay or Prevent the Onset of Primary Open- Angle Glaucoma: The Ocular Hypertension Treatment Study (OHTS) 85
16. Intraocular Pressure Control and Long- Term Visual Field Loss in Open- Angle Glaucoma: Collaborative Initial Glaucoma Treatment Study (CIGTS) 91
17. Latanoprost for Open- Angle Glaucoma: United Kingdom Glaucoma Treatment Study (UKGTS) 97
18. Tube Shunt Surgery Versus Trabeculectomy in Eyes with Prior Ocular Surgery and Uncontrolled Glaucoma: Tube Versus Trabeculectomy (TVT) Study 103
19. Pooled Data Analysis of the Ahmed Baerveldt Comparison Study and the Ahmed Versus Baerveldt Study: Ahmed Baerveldt Comparison (ABC) Study, Ahmed Versus Baerveldt (AVB) Study 109
20. Risk Factors for Branch and Central Retinal Vein Occlusion: The Eye Disease Case- Control Study 115
21. Argon Laser Photocoagulation for Macular Edema in Branch Vein Occlusion: The Branch Vein Occlusion Study (BVOS) 121
22. Intraocular Injections of Ranibizumab in Patients with Macular Edema Following Branch Retinal Vein Occlusion: Ranibizumab for Macular Edema Following Branch Retinal Vein Occlusion (BRAVO) Study 127
23. Grid Pattern Photocoagulation for Macular Edema in Central Vein Occlusion: The Central Vein Occlusion Study (CVOS) 133
24. Steroids in the Treatment of Central Retinal Vein Occlusion: The Standard Care vs. Corticosteroid for Retinal Vein Occlusion (SCORE- CRVO) Study 139
25. Cryotherapy for Retinopathy of Prematurity: Cryotherapy for Retinopathy of Prematurity (CRYO- ROP) Study 145
26. Supplemental Therapeutic Oxygen for Prethreshold Retinopathy of Prematurity: The Supplemental Therapeutic Oxygen for Prethreshold Retinopathy of Prematurity (STOP- ROP) Trial 151
27. Early Treatment of Prethreshold Retinopathy of Prematurity: Early Treatment for Retinopathy of Prematurity (ETROP) Study 157
28. Intravitreal Bevacizumab for Stage 3+ Retinopathy of Prematurity: Bevacizumab Eliminates the Angiogenic Threat of Retinopathy of Prematurity (BEAT- ROP) Study 163
29. Photocoagulation for Diabetic Macular Edema: Early Treatment Diabetic Retinopathy Study (ETDRS) Report Number 1 169
30. Early Photocoagulation for Diabetic Retinopathy: Early Treatment Diabetic Retinopathy Study (ETDRS) Report Number 9 177
31. Does Pars Plana Vitrectomy Improve Visual Outcomes in Patients with Complications of Proliferative Diabetic Retinopathy: Early Treatment Diabetic Retinopathy Study (ETDRS) Report Number 17 185
32. Intensive Diabetes Management to Reduce the Risk of Retinopathy Developing or Progressing: The Diabetes Control and Complications Trial (DCCT) 191
33. Progression of Retinopathy and Vision Loss Related to Tight Blood Pressure Control in Type 2 Diabetes Mellitus: UK Prospective Diabetes Study (UKPDS) Hypertension in Diabetes Study 199
34. Immediate Vitrectomy and Intravenous Antibiotics for the Treatment of Postoperative Bacterial Endophthalmitis: Endophthalmitis Vitrectomy Study (EVS) 207
35. Prevalence of Age- Related Maculopathy: The Beaver Dam Eye Study 213
36. Does High- Dose Supplementation with Vitamins C and E, Beta Carotene, and Zinc Slow the Progression of Age- Related Macular Degeneration and Vision Loss? Age- Related Eye Disease Study (AREDS) 219
37. Argon Laser Photocoagulation for Extrafoveal Neovascular Maculopathy: Macular Photocoagulation Study 225
38. Photodynamic Therapy of Subfoveal Choroidal Neovascularization in Age- Related Macular Degeneration with Verteporfin: Treatment of Age- Related Macular Degeneration with Photodynamic Therapy (TAP) Study 231
39. Pegaptanib for Neovascular Age- Related Macular Degeneration:   VEGF Inhibition Study in Ocular Neovascularization (V.I.S.I.O.N.) Clinical Trial 239
40. Ranibizumab for Neovascular Age- Related Macular Degeneration: Minimally Classic/ Occult Trial of the Anti- VEGF Antibody Ranibizumab in the Treatment of Neovascular AMD (MARINA) 245
41. Ranibizumab and Bevacizumab for Neovascular Age- Related Macular Degeneration: Comparison of Age- Related Macular Degeneration Treatments Trials (CATT) 251
42. Effect of Pre- Enucleation Radiation on Mortality in Large Choroidal Melanomas: The Collaborative Ocular Melanoma Study (COMS) Randomized Trial of Pre- enucleation Radiation of Large Choroidal
43. Systemic Anti- Inflammatory Therapy Versus Fluocinolone Acetonide: Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow- Up Study 263
44. Botulinum A Toxin Injection into Extraocular Muscles as an Alternative to Strabismus Surgery 269
45. Botulinum A Toxin Injection as a Treatment for Blepharospasm 275
46. A Clinical Activity Score That Discriminates Between Inflammatory and Noninflammatory Graves’ Ophthalmopathy 279
47. Corticosteroids in the Treatment of Acute Optic Neuritis: The Optic Neuritis Treatment Trial 285
48. Atropine or Patching for Treatment of Moderate Amblyopia in Children: Patching vs. Atropine Trial 291
49. Contact Lens Versus Intraocular Lens Correction of Monocular Aphakia During Infancy: The Infant Aphakia Treatment Study 297
50. Effect of Acetazolamide on Visual Function in Patients with Idiopathic Intracranial Hypertension and Mild Visual Loss: The Idiopathic Intracranial Hypertension Treatment Trial 303
Index 309