34th Hemophilia Symposium: Hamburg 2003

HIV Infection and Causes of Death in Patients with Hemophilia in Germany (Year 2002/2003 Survey)....Pages 3-13
Hemophilia in Austria — The Annual Survey of the Austrian Hemophilia Centers....Pages 14-18
Lithuanian Hemophilia Register: Update 2003....Pages 19-21
Guidelines for Treatment of Patients with Hemophilia and Inhibitors....Pages 25-32
Bolus Injection of Recombinant Factor VIIa (NovoSeven) can be More Effective than Continuous Infusion in Inhibitor Patients with Severe Hemophilia A....Pages 33-37
The Role of Therapy Regimen and Age at First Exposure on Inhibitor Development in Patients with Severe Hemophilia A....Pages 38-41
Presentation of the Inhibitor-Immunology-Study....Pages 42-47
Current Clinical Investigations Involving FEIBA....Pages 48-51
Major Orthopedic Reconstructions in an Inhibitor Patient — A Case Report....Pages 55-58
Total Hip Replacement in Patients with Severe Bleeding Disorders A 30 Years Single Center Experience....Pages 59-63
MRI Staging of Hemophilic Joints in Comparison with the Radiological Score and the Clinical Dates of Children and Young Adults....Pages 64-70
Orthopedic Knee Replacement in Hemophilic Patients....Pages 71-76
Treatment of Adults with Sepsis-Induced Coagulopathy and Purpura Fulminans with a Plasma-Derived Protein C Concentrate (Ceprotin)....Pages 79-88
Comparison of the Anticoagulant Action of Recombinant Human Activated Protein C in Cord with that in Adult Plasma....Pages 89-93
The Relationship between Protein C Activity and the Endogenous Thrombin Potential in Controls and Septic Patients....Pages 94-100
Antibodies Against Annexin V, Cardiolipin and β 2 -Glycoprotein 1 or APC-Resistance in Patients with Recurrent Miscarriage or In-Vitro-Fertilization-Failures....Pages 103-106
Diagnostics of Platelet Function Disorders by Lumi-Aggregometry — Results and Comparison of Methods....Pages 107-115
Management of a Premature Infant below 1500 g with Hemophilia A....Pages 116-118
Elevated Factor VIIIC: Ag in Children with Venous Thrombosis and Stroke — Preliminary Results of a Case-Control Study....Pages 119-124
Functional Disorders and Treatment Modalities in Hemophilic Children....Pages 125-134
HLA Profile in Acquired Hemophilia....Pages 137-141
Characterization of Polyclonal Factor VIII-Inhibitory Antibodies....Pages 142-152
Frequency and Inhibitor Risk of the Intron-1-Inversion Mutation in the German Hemophilia Population....Pages 153-155
Effect of FVIII on Clotting Time and Thrombin Potential in Tissue Factor-Activated Hemophilia A Plasma....Pages 156-161
Bleeding Tendency in Factor XI Deficiency: Report on two Families and the Detection of a Novel Mutation within the Factor XI Gene....Pages 165-169
Multiple Distal Pseudotumours in a Patient with Severe Hemophilia A and High Titer Inhibitors....Pages 170-177
HIV Resistance to Antiretroviral Therapy in Romania....Pages 178-181
Ileopsoas Hemophilic Pseudotumour with Externalized Bowel Fistulation....Pages 182-187
Reduction of Proteoglycan Synthesis in Chondrocytes Depending on Concentration and Duration of Iron Overload....Pages 188-190
Bleeding Tendency of Carriers of Hemophilia A — Dependent on the Age of the Carriers?....Pages 191-195
Clinical Investigation of Orthopedic Outcome in Patients with Severe Hemophilia Under Prophylactic Treatment. Disadvantage of a late Prophylactic Treatment?....Pages 196-198
Operative Treatment of Ankle Equinus Deformity in Hemophiliacs....Pages 199-204
Spontaneous Empyema of Joints and Staphylococcal Sepsis in a Patient with Severe Hemophilia A....Pages 205-206
The Role of VWF:Ag II in Patients with Acquired von Willebrand Disease....Pages 207-211
Contamination of Coagulation Factor Concentrates with Human Parvovirus Genotype 2 DNA is Less Frequent than Contamination with Genotype 1 (B19) DNA....Pages 212-224
The Hemophilia Assistant in Germany....Pages 225-227
“Need” in Hemophilia A — a Qualitative Study....Pages 228-231
Fit for Life — Fitness Levels of Young Hemophiliacs Today....Pages 232-237
The Austrian “Haemofit-Program” - a two Years work-out Experience of People with Hemophilia (PwH)....Pages 238-241
Methods for Testing Pharmacodynamic Variables of Hemophilia and Inhibitor Therapy: Thrombin Generation Assay and Other Tests....Pages 245-252
Immune Tolerance in an Inhibitor Patient with Severe Hemophilia A — Comparison of two Different Treatment Schedules Including Rituximab....Pages 253-256
The Endogenous Thrombin Potential as a Monitoring Parameter in a Patient with an Acquired Hemophilia A....Pages 257-260
Case report: 58-Year-Old Hemophilia A Patient with High-Titer Inhibitor Development and Introduction of a Multicenter PTP-Inhibitor Study....Pages 261-263
First Data of a Prospective Study About Incidence of Inhibitors During and After Continuous Infusion of Different Factor Concentrates Given During and After Surgical Procedures in Hemophilia A or B and von Willebrand Disease....Pages 264-266
Acquired Thrombophilia in Patients on Hemodialysis with Recurrent Vascular Access Thrombosis....Pages 269-271
Is Travelling a Risk Factor for Venous Thrombosis in Individuals with Factor V Leiden in Heterozygous Form?....Pages 272-274
Popliteal Artery Embolism in Abdominal Aortal Thrombus with Liver Abscesses Caused by Heterozygous Prothrombin Mutation with Protein S Deficiency and Factor VIII Elevation....Pages 275-276
Effect of the new Direct Thrombin Inhibitor Melagatran in Cord and Adult Plasma: an in-vitro Examination....Pages 277-287
Higher Concentrations of Heparin and Hirudin are Required to Inhibit Thrombin Generation in Tissue Factor-Activated Cord Compared to Adult Plasma....Pages 288-297
Molecular Genetic Analysis in Patients with Inherited Thrombophilia and Antithrombin, Protein C or Protein S Deficiency....Pages 298-301
Analysis of Thrombophilic Risk Factors in Patients Suffering from Ocular Thrombotic Complications....Pages 302-303
Protein C Concentrate for the Treatment of Veno Occlusive Disease in a boy with Nephroblastoma....Pages 304-306
Homozygous Factor X Gene Mutation Gly380Arg is Associated to Perinatal Intracranial Hemorrhage....Pages 309-313
Mutation Analysis of the C1 Inhibitor Gene....Pages 314-316
Novel and Recurrent Mutations in the Gamma-Glutamyl Carboxylase (GGCX) Gene....Pages 317-320
First Case of Compound Heterozygous Mutations in the Kininogen Gene Causing Severe High Molecular Weight Kininogen Deficiency....Pages 321-326
Sequence of the rat Factor VIII cDNA....Pages 327-330
Mutation Profiling in Congenital FXIIIA Deficiency: Detection of 6 Novel Mutations....Pages 331-333
Functional Analysis of the Factor VIII B Domain....Pages 334-337
Expressing Recombinant Coagulation Factors in Yeast and Insect Cells....Pages 338-340
Long Term Optimisation of F8 Gene Mutation Screening by DHPLC....Pages 341-343
Expression Studies of Recombinant FVIII Proteins Exhibiting Mutations in the B-Domain....Pages 344-347
Genetic Variability of the Factor VIII Gene in the Normal Population....Pages 348-350
Three Novel Microdeletions and the First Insertion / Deletion in Patients with Factor X Deficiency....Pages 351-354
SNP Map of the Protein C Gene....Pages 355-357
Characterization of Factor VIII-Von Willebrand Factor (FVIII-VWF)-Complex Concentrates Under Shear Stress....Pages 361-367
Procedural Rules of a National Hemophilia Register in Germany....Pages 368-368
Quality Management of Clotting Factor Replacement Therapy in Medical Institutions — Advantage or Obligation....Pages 369-372
Proteus Syndrome: Successful Therapy of Severe Migraine Symptoms with low Molecular Weight Heparin....Pages 373-377
Administration of Recombinant Factor FVIIa (NovoSeven, NovoNordisk) in a Patient with Glanzmann Thrombasthenia....Pages 378-379
Combined Heterozygous Factor XIII-Deficiency in a Family Case Report....Pages 380-382
Resistance to Coumarin in a 55-year-old Patient with Chronic Arrhythmia....Pages 383-384
Investigation of the Tendency to Bleeding in Patients with low Activity of Plasminogen Activator Inhibitor-1 (PAI-1)....Pages 385-388
The Importance of Pre-Analytic Conditions on the Determination of VWF Parameters....Pages 389-393
Recombinant FVIIa in Chemotherapy Related Thrombocytopenic Bleedings....Pages 394-395