Lipoprotein Metabolism and Atherogenesis

Front Matter....Pages II-XVIII
Front Matter....Pages 1-1
Lipoprotein Metabolism and Atherogenesis....Pages 3-11
Role Of Lipid Concentrations and Apolipoproteins In Altering ApoB Metabolism and Promoting Coronary Events....Pages 12-18
Long-term Effect of LDL-Apheresis on Familial Hypercholesterolemia Homozygotes....Pages 19-25
Molecular mechanism of visceral obesity....Pages 26-33
Diabetes and Atherosclerosis....Pages 34-36
Front Matter....Pages 37-37
Molecular Genetics and Clinical Features of Japanese Patients with Familial Hypercholesterolemia....Pages 39-43
Molecular Analysis of Apolipoprotein A-I and E Mutants in Japan....Pages 44-47
Novel mutations of the LDL Receptor Gene in Familial Hypercholesterolemia Pedigrees in Hokkaido....Pages 48-50
Preheparin Lipoprotein Lipase Mass Might Reflect the Amount of Working Lipoprotein Lipase in the Whole Body....Pages 51-53
Quantitative Trait Loci (QTLs) for Serum Cholesterol Levels in the Stroke-Prone Spontaneously Hypertensive Rats (SHRSP)....Pages 54-55
Evidence of linkage in familial combined hyperlipidemia to chromosome 1q21-q23....Pages 56-58
Molecular Analysis on the LDL Receptors in Two Patients with Homozygous Familial Hypercholesterolemia....Pages 59-61
Common Mutation of 5, 10-Methylenetetrahydrofolate Reductase Accelerates Coronary Artery Disease in Familial Hypercholesterolemia....Pages 62-64
Effect of troglitazone on plasma lipid metabolism and lipoprotein lipase....Pages 65-67
Combination of LPL gene exon 9 Ser447→Ter nonsense mutation and Apo ε 2 allele might contribute to development of hypertriglyceridemia....Pages 68-70
Improvement by Thiazolidinediones of Vascular Endothelial Cell Dysfunction in Diabetic Patients: A Possible New Physiological Role of PPARγ....Pages 71-73
Beneficial Effect of Gemfibrozil on LDL Chemicophysical Characteristics and Oxidizability....Pages 74-76
Inhibitory Effect of HMG-CoA Reductase Inhibitors for the Development and Progression of Intimal-medial Thickness in Carotid Artery in Type 2 Diabetes Mellitus with Hypercholesterolemia....Pages 77-79
Plasma phosphatidylcholine hydroperoxide concentrations in normal subjects and patients with hyperlipidemia....Pages 80-81
Front Matter....Pages 83-83
Lipid Transfer Proteins and Receptors in HDL Metabolism....Pages 85-87
Front Matter....Pages 83-83
PPARs and Atherosclerosis....Pages 88-95
Molecular Basis of Cellular Cholesterol Efflux and Regulation of Plasma HDL Level....Pages 96-103
Roles of Apolipoprotein E Receptors in Lipoprotein Metabolism....Pages 104-107
The structure and function of the scavenger receptor class A....Pages 108-114
Impairment of Reverse Cholesterol Transport System and Atherosclerosis....Pages 115-123
ACAT Genes and Proteins in Humans....Pages 124-129
Caveolin is a Cholesterol-binding Protein....Pages 130-136
 In vivo Functions of SREBPs....Pages 137-141
Molecular Characterization of Arachidonate Preferring Acyl-CoA Synthetase, ACS4....Pages 142-143
Molecular Characterization of Short-Chain Acyl-CoA Synthetases....Pages 144-145
Expression of the VLDL Receptor is Up-Regulated by Cell Differentiation in HL-60 Cells....Pages 146-148
Transcriptional Regulation of the Genes for Human HMG CoA Synthase and Squalene Synthase by SREBP and NF-Y....Pages 149-151
Expression of ACYL-Coenzyme A:Cholesterol Acyltransferase-1 (ACAT-1) Protein in Human Atherosclerotic Lesions and Cultured Monocytes-Macrophages....Pages 152-153
Relationship Between Postprandial Triglyceride Level and Intima-Media Thickness of Carotid Artery after Troglitazone Treatment in Type 2 Diabetes....Pages 154-156
A New Rabbit Strain with Heritable Hypercholesterolemia and Hypertriglyceridemia....Pages 157-159
Turnover of Glutathione and Ascorbic Acid is Suppressed in Hyperlipidemic Rabbits....Pages 160-162
Pravastatin, an HMG-CoA Reductase Inhibitor, is Transported by Rat Organic Anion Transporting Polypeptide, oatp2....Pages 163-165
Front Matter....Pages 167-167
The puzzling ligands for scavenger receptors....Pages 169-175
Granulocyte Macrophage Colony-stimulating Factor is involved in Murine Macrophage Proliferation Induced by Oxidized Low Density Lipoprotein....Pages 176-183
Mast Cells in Atherogenesis: A Model for Studying Proteolytic Modification of Low and High Density Lipoproteins....Pages 184-192
Front Matter....Pages 167-167
LOX-1, an endothelial receptor for oxidized LDL Implications for induction of endothelium dysfunction in the pathogenesis of vascular diseases....Pages 193-198
Inducible Expression of Lectin-like Oxidized Low Density Lipoprotein Receptor-1 in Vascular Endothelial Cells and Macrophages....Pages 199-206
Identification and Characterization of a PDZ Domain-containing Protein That Interacts with the HDL Receptor SR-BI....Pages 207-209
Structure and Function of Human SREC (Scavenger Receptor expressed by Endothelial Cells), A Novel Receptor for Modified LDL....Pages 210-212
Apoptosis in Atherosclerosis: Induction of Apoptosis by Oxidized Low Density Lipoprotein and Oxysterols....Pages 213-218
Combination treatment with an insulin action enhancer and an inhibitor of HMG-CoA reductase shows a synergistic effect on atherosclerosis of WHHL rabbits....Pages 219-223
Reduced Secretion of Tumor Necrosis Factor-α and Interleukin-1β from Monocyte-Derived Macrophages of CD36-Deficient Subjects in Response to Oxidized LDL....Pages 224-226
CD36 Expression in Human Monocytic Leukemia Cell Lines: THP-1 and THP-1 Subtype, Show Different Expressions of Type I and Type II Scavenger Receptors....Pages 227-229
Front Matter....Pages 230-232
Alteration of smooth muscle cell phenotype in diabetic vascular wall: From the molecular point of view....Pages 233-233
The Vascular Nitric Oxide/Superoxide System and Atherosclerosis....Pages 235-242
Antagonistic Monoclonal Antibody against Receptor Tyrosine Kinases: A Novel Strategy to Study the Role of Monocyte/Macrophage in Atherogenesis in vivo ....Pages 243-245
Rac1 and CDC42Hs play a critical role in MCP-1-induced chemotaxis....Pages 246-253
Stimulation of mitogen-activated kinases by lysophosphatidylcholine in bovine aortic endothelial cells....Pages 254-256
Ca 2+ -Dependent Activation of the 33-kDa Thrombin Receptor-Associated Kinase in Human Platelets....Pages 257-259
Lysophosphatidylcholine generates superoxide anions through activation of phosphatidylinositol 3-kinase in human neutrophils....Pages 260-262
PDGF Enhanced 7-Ketocholesterol-induced Apoptosis of Vascular Smooth Muscle Cell, accompaning with c-myc Expression....Pages 263-265
Adventitia-derived Macrophages Contribute to the Formation of Coronary Arteriosclerotic Lesions in Pigs in Vivo-Potentiating Effect of Oxidative Stress-....Pages 266-268
Expression of CD36 in Cultured Human Aortic Smooth Muscle Cells (HASMCs)....Pages 269-271
Induction of Macrophage VEGF in Response to Oxidized LDL and VEGF Accumulation in Human Atherosclerotic Lesion....Pages 272-274
Front Matter....Pages 275-277
F-1394, an ACAT Inhibitor, Inhibits Neointimal Thickening and Macrophage Accumulation after Balloon Injury in the Cholesterol-Fed Rabbit....Pages 233-233
Back Matter....Pages 278-280
....Pages 281-283