Wound Healing and Skin Physiology

Front Matter....Pages I-XV
Front Matter....Pages 1-1
Theory and Practice of Wound Healing in the Past....Pages 3-18
 De rara medicatione vulnerum : An Historical Approach to Wound Care....Pages 19-24
Front Matter....Pages 25-25
Fetal Wound Repair....Pages 27-31
Histological Examination of Skin Grafts....Pages 33-43
Reepithelialisation of Wounds....Pages 45-60
Pathophysiology of Wound Healing in Venous Leg Ulcers....Pages 61-69
Collagen Metabolism and Wound Contraction....Pages 71-88
The Role of the Connective Tissue Matrix in Wound Healing: Fibroblast and Collagen Interactions....Pages 89-104
Modulation of Fibroblastic Cytoskeletal Features During Wound Healing and Fibrosis....Pages 105-112
Front Matter....Pages 113-113
Measurement of Microcirculation....Pages 115-126
Spatial Pattern of Cutaneous Perfusion in Wound Healing....Pages 127-136
The Vascular Architecture of the Keloid: A Scanning Electron Microscope Study on Vascular Corrosion Casts....Pages 137-151
Growth Factor Control of Wound Healing Angiogenesis....Pages 153-161
Blood Flow in Ulcerated Tissue and Surrounding Skin: Healing Correlates with Return of the Venoarteriolar Reflex....Pages 163-167
Three-Dimensional Reconstruction of Terminal Blood Spaces in the Proximal Tibia Metaphysis of the Growing Rat — A Model to Study Normal Angiogenesis....Pages 169-179
Front Matter....Pages 181-181
Trace Elements in Normal and Impaired Wound Healing....Pages 183-199
Plasmin-Mediated Pericellular Proteolysis by Keratinocytes: Extracellular Matrix Reorganization vs Tissue Damage....Pages 201-211
Reduced Migration Potential of Epithelial Cells from Explants of Chronic Decubitus Ulcers: The Cause of Impaired Wound Healing?....Pages 213-217
Fibronectin and Its Role in Wound Healing....Pages 219-226
Mechanisms of Action of Collagenase in Wound Repair....Pages 227-237
Front Matter....Pages 181-181
Studies of Growth Factor and Matrix Proteinase Activities During Early Stages of Wound Healing....Pages 239-243
Regulatory Aspects of Collagen Synthesis in Fibroblasts from Human Colon and Skin....Pages 245-254
Platelet Released Factors Stimulate Rat Burn Wound Contraction....Pages 255-265
Front Matter....Pages 267-267
Biologic Activity of Tissue Flaps in the Treatment of Complicated Wounds....Pages 269-275
Studies on Wound Healing in Axial Pattern Flaps of the Diabetic Rat....Pages 277-283
Endogenous Growth Factor Pathways May Regulate Epidermal Hyperplasia in Chronic Venous Wounds: Modulation by Hydrocolloid Dressings....Pages 285-302
Immunohistochemical Effect of a Hydrocolloid Occlusive Dressing (DuoDERM E) in Psoriasis Vulgaris....Pages 303-305
The Treatment of Malum Perforans Pedis: Operative and Conservative Therapy....Pages 307-313
Phosphocreatine Ameliorates Structural Integrity of Ischemic Skin Flaps....Pages 315-327
Granulocyte Activity Is Enhanced by Culture Supernatants of Mononuclear Leukocytes Incubated with Tetrachlorodecaoxide....Pages 329-334
Skin Reactions and Sensations Induced by Intradermal Injection of Substance P into Compound 48/80 Pretreated Skin....Pages 335-344
Effect of Wound Fluid on Cultured Keratinocytes....Pages 345-349
Strategies of Keratinocytes and Fibroblasts in Wound Closure Observed in an In Vitro Model....Pages 351-357
Interleukin-2 Improves Transfusion-Suppressed Repair of Experimental Intestinal Anastomoses....Pages 359-365
Neuropeptides and Merkel Cells in Tissue Expansion....Pages 367-380
Congenital Factor XIII Deficiency as Cause of Therapy-Resistant Burn Wounds....Pages 381-383
Front Matter....Pages 385-385
The Microbiology of Wounds....Pages 387-391
Pathogenesis of Wound Infections....Pages 393-411
Interaction of Bacteria with Host Defense Cells: Mechanisms of Burn Wound Sepsis....Pages 413-421
 Streptococcus pyogenes Induced Necrosis and Ulcers of the Skin: The Possible Role of Streptococcal Exotoxins....Pages 423-434
Front Matter....Pages 385-385
Inhibition of Wound Healing by Topical Anti-microbial Agents....Pages 435-448
Intra-arterial Application of Ceftizoxime Supports Wound Healing in Infected Ischemic Lesions of the Limbs....Pages 449-453
Front Matter....Pages 455-455
Noninvasive Measurement of Wound Healing of the Skin....Pages 457-479
Computerized Wound Analysis — A New Method for Assessment of Healing....Pages 481-483
A Color Image Analysis System (CD-CWA) for the Quantification of Wound Healing in Multicenter Trials....Pages 485-496
Noninvasive Assessment of the Physical Properties of the Skin....Pages 497-503
Noninvasive Evaluation of Skin Barrier Function....Pages 505-511
A Cellstick Device for Wound Healing Research....Pages 513-522
High-Resolution Ultrasound Imaging of Various Types of Wounds....Pages 523-531
A 20 MHz Ultrasound Examination of Lipodermatosclerosis....Pages 533-538
Physiological Changes in Aging Skin....Pages 539-541
Diagnosis and Treatment of Venous Diseases and Leg Ulcer....Pages 543-547
Front Matter....Pages 549-549
Wound Healing in Oncologic Dermatosurgery....Pages 551-559
Treatment of Keloids and Hypertrophic Scars with Cryosurgery and Silicon Gel Sheeting....Pages 561-569
Surgery of Venous Leg Ulcers....Pages 571-580
Treatment of Venous Leg Ulcers with a Soft Laser Light....Pages 581-584
Front Matter....Pages 585-585
Dressings as a New Concept for Topical Treatment of Ulcers....Pages 587-599
The Effect of Allopurinol on Wound Contraction and Granulation Tissue Formation in the Rat....Pages 601-608
Effects of Pale Ichthyol in a Model of Impaired Wound Healing....Pages 609-615
Pretreatment of Photodamaged Forearm Skin with Topical Tretinoin Accelerates Healing of Full-Thickness Wounds....Pages 617-630
Front Matter....Pages 585-585
Treatment of Chronic Wounds with Cultured Keratinocytes....Pages 631-633
Influence of Agents Used for Topical Wound Treatment on Phagocyte Stimulation and Fibroblast Growth....Pages 635-642
Both Wet and Moist Wound Environments Accelerate Cutaneous Healing....Pages 643-646
Comparative Experimental Study on the Treatment of Open Wounds....Pages 647-655
Comparison of Varihesive E with the Conventional Tulle Gras Dressing in Skin Graft Donor Sites Treatment of Infants....Pages 657-665
Hydrocolloid Dressings in the Therapy of Cryolesions....Pages 667-680
Treatment of Venous Leg Ulcers Using Occlusive Hydrocolloid Dressings (Varihesive E) Versus Conventional Phase-Adapted Wound Dressing....Pages 681-687
Weekly Treatment of Psoriatic Plaques with the Hydrocolloid Dressing DuoDERM E in Combination with Triamcinolone Acetonide....Pages 689-691
Covering Tattoo Dermabrasion Wounds with a Hydrocolloid Dressing (Varihesive E)....Pages 693-702
A Prospective Randomized Study of the Efficacy of Hydrogel, Hydrocolloid, and Saline Moistened Dressings on the Management of Pressure Ulcers....Pages 703-707
Pericapillary Fibrin in Venous Ulcers Treated with Hydrocolloid Dressing....Pages 709-717
Back Matter....Pages 719-719