Williams Hematology, 9E (MEDICAL/DENISTRY)

Cover
Title Page
Copyright Page
Contents
Contributors
Preface
Part I: Clinical Evaluation of the Patient
	1. Initial Approach to the Patient: History and Physical Examination
	2. Examination of Blood Cells
	3. Examination of The Marrow
	4. Consultative Hematology
Part II: The Organization of the Lymphohematopoietic Tissues
	5. Structure of the Marrow and the Hematopoietic Microenvironment
	6. The Organization and Structure of Lymphoid Tissues
Part III: Epochal Hematology
	7. Hematology of the Fetus and Newborn
	8. Hematology during Pregnancy
	9. Hematology in Older Persons
Part IV: Molecular and Cellular Hematology
	10. Genetic Principles and Molecular Biology
	11. Genomics
	12. Epigenetics
	13. Cytogenetics and Genetic Abnormalities
	14. Metabolism of Hematologic Neoplastic Cells
	15. Apoptosis Mechanisms: Relevance to the Hematopoietic System
	16. Cell-Cycle Regulation and Hematologic Disorders
	17. Signal Transduction Pathways
	18. Hematopoietic Stem Cells, Progenitors, and Cytokines
	19. The Inflammatory Response
	20. Innate Immunity
	21. Dendritic Cells and Adaptive Immunity
Part V: Therapeutic Principles
	22. Pharmacology and Toxicity of Antineoplastic Drugs
	23. Hematopoietic Cell Transplantation
	24. Treatment of Infections in The Immunocompromised Host
	25. Antithrombotic Therapy
	26. Immune Cell Therapy
	27. Vaccine Therapy
	28. Therapeutic Apheresis: Indications, Efficacy, and Complications
	29. Gene Therapy for Hematologic Diseases
	30. Regenerative Medicine: Multipotential Cell Therapy for Tissue Repair
Part VI: The Erythrocyte
	31. Structure and Composition of the Erythrocyte
	32. Erythropoiesis
	33. Erythrocyte Turnover
	34. Clinical Manifestations and Classification of Erythrocyte Disorders
	35. Aplastic Anemia: Acquired and Inherited
	36. Pure Red Cell Aplasia
	37. Anemia of Chronic Disease
	38. Erythropoietic Effects of Endocrine Disorders
	39. The Congenital Dyserythropoietic Anemias
	40. Paroxysmal Nocturnal Hemoglobinuria
	41. Folate, Cobalamin, and Megaloblastic Anemias
	42. Iron Metabolism
	43. Iron Deficiency and Overload
	44. Anemia Resulting from Other Nutritional Deficiencies
	45. Anemia Associated with Marrow Infiltration
	46. Erythrocyte Membrane Disorders
	47. Erythrocyte Enzyme Disorders
	48. The Thalassemias: Disorders of Globin Synthesis
	49. Disorders of Hemoglobin Structure: Sickle Cell Anemia and Related Abnormalities
	50. Methemoglobinemia and Other Dyshemoglobinemias
	51. Fragmentation Hemolytic Anemia
	52. Erythrocyte Disorders as a Result of Chemical and Physical Agents
	53. Hemolytic Anemia Resulting from Infections with Microorganisms
	54. Hemolytic Anemia Resulting from Immune Injury
	55. Alloimmune Hemolytic Disease of the Fetus and Newborn
	56. Hypersplenism and Hyposplenism
	57. Primary and Secondary Erythrocytoses
	58. The Porphyrias
	59. Polyclonal and Hereditary Sideroblastic Anemias
Part VII: Neutrophils, Eosinophils, Basophils, and Mast Cells
	60. Structure and Composition of Neutrophils, Eosinophils, and Basophils
	61. Production, Distribution, and Fate of Neutrophils
	62. Eosinophils and Related Disorders
	63. Basophils, Mast Cells, and Related Disorders
	64. Classification and Clinical Manifestations of Neutrophil Disorders
	65. Neutropenia and Neutrophilia
	66. Disorders of Neutrophil Function
Part VIII: Monocytes and Macrophages
	67. Structure, Receptors, and Functions of Monocytes and Macrophages
	68. Production, Distribution, and Activation of Monocytes and Macrophages
	69. Classification and Clinical Manifestations of Disorders of Monocytes and Macrophages
	70. Monocytosis and Monocytopenia
	71. Inflammatory and Malignant Histiocytosis
	72. Gaucher Disease and Related Lysosomal Storage Diseases
Part IX: Lymphocytes and Plasma Cells
	73. The Structure of Lymphocytes and Plasma Cells
	74. Lymphopoiesis
	75. Functions of B Lymphocytes and Plasma Cells in Immunoglobulin Production
	76. Functions of T Lymphocytes: T-Cell Receptors for Antigen
	77. Functions of Natural Killer Cells
	78. Classification and Clinical Manifestations of Lymphocyte and Plasma Cell Disorders
	79. Lymphocytosis and Lymphocytopenia
	80. Immunodeficiency Diseases
	81. Hematologic Manifestations of Acquired Immunodeficiency Syndrome
	82. Mononucleosis Syndromes
Part X: Malignant Myeloid Diseases
	83. Classification and Clinical Manifestations of the Clonal Myeloid Disorders
	84. Polycythemia Vera
	85. Essential Thrombocythemia
	86. Primary Myelofibrosis
	87. Myelodysplastic Syndromes
	88. Acute Myelogenous Leukemia
	89. Chronic Myelogenous Leukemia and Related Disorders
Part XI: Malignant Lymphoid Diseases
	90. Classification of Malignant Lymphoid Disorders
	91. Acute Lymphoblastic Leukemia
	92. Chronic Lymphocytic Leukemia
	93. Hairy Cell Leukemia
	94. Large Granular Lymphocytic Leukemia
	95. General Considerations for Lymphomas: Epidemiology, Etiology, Heterogeneity, and Primary Extranodal Disease
	96. Pathology of Lymphomas
	97. Hodgkin Lymphoma
	98. Diffuse Large B-Cell Lymphoma and Related Diseases
	99. Follicular Lymphoma
	100. Mantle Cell Lymphoma
	101. Marginal Zone B-Cell Lymphomas
	102. Burkitt Lymphoma
	103. Cutaneous T-Cell Lymphoma (Mycosis Fungoides and Sézary Syndrome)
	104. Mature T-Cell and Natural Killer Cell Lymphomas
	105. Plasma Cell Neoplasms: General Considerations
	106. Essential Monoclonal Gammopathy
	107. Myeloma
	108. Immunoglobulin Light-Chain Amyloidosis
	109. Macroglobulinemia
	110. Heavy-Chain Disease
Part XII: Hemostasis and Thrombosis
	111. Megakaryopoiesis and Thrombopoiesis
	112. Platelet Morphology, Biochemistry, and Function
	113. Molecular Biology and Biochemistry of the Coagulation Factors and Pathways of Hemostasis
	114. Control of Coagulation Reactions
	115. Vascular Function in Hemostasis
	116. Classification, Clinical Manifestations, and Evaluation of Disorders of Hemostasis
	117. Thrombocytopenia
	118. Heparin-Induced Thrombocytopenia
	119. Reactive Thrombocytosis
	120. Hereditary Qualitative Platelet Disorders
	121. Acquired Qualitative Platelet Disorders
	122. The Vascular Purpuras
	123. Hemophilia A and Hemophilia B
	124. Inherited Deficiencies of Coagulation Factors II, V, V+VIII, VII, X, XI, and XIII
	125. Hereditary Fibrinogen Abnormalities
	126. von Willebrand Disease
	127. Antibody-Mediated Coagulation Factor Deficiencies
	128. Hemostatic Alterations in Liver Disease and Liver Transplantation
	129. Disseminated Intravascular Coagulation
	130. Hereditary Thrombophilia
	131. The Antiphospholipid Syndrome
	132. Thrombotic Microangiopathies
	133. Venous Thrombosis
	134. Atherothrombosis: Disease Initiation, Progression, and Treatment
	135. Fibrinolysis and Thrombolysis
Part XIII: Transfusion Medicine
	136. Erythrocyte Antigens and Antibodies
	137. Human Leukocyte and Platelet Antigens
	138. Blood Procurement and Red Cell Transfusion
	139. Preservation and Clinical Use of Platelets
Index
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