White Blood: Personal Journeys With Childhood Leukaemia

CONTENTS......Page 6
Preface......Page 8
List of Figures......Page 14
List of Paintings......Page 16
A Scientist......Page 18
A Family......Page 19
A Paediatric Psychologist......Page 20
The Artist: Susan Macfarlane......Page 22
1. Introduction to Childhood Leukaemia Mel Greaves and Donald Pinkel......Page 28
2. A Paediatrician’s Journey Donald Pinkel......Page 38
Types of Childhood ALL......Page 39
Early Treatment of Childhood ALL......Page 40
Working with Professor Sidney Farber......Page 45
Paediatrics at Roswell Park Cancer Center......Page 47
St Jude Children’s Research Hospital......Page 49
“Total Therapy” of ALL......Page 52
Total Therapy Studies I to III......Page 55
Total Therapy Study IV......Page 56
Total Therapy Study V......Page 57
Total Therapy Studies VI to VIII......Page 59
Curative Therapy of Childhood ALL, 1975–2008......Page 63
“Spin-offs” of Total Therapy Studies......Page 67
Current Challenges......Page 69
Technical References......Page 71
3. A Scientist’s Journey Mel Greaves......Page 74
Questions, Questions and Yet More Questions......Page 75
Who’s Who?......Page 77
When Does it Start: Early Beginnings?......Page 81
Twins Show the Way......Page 82
Forensic Blood Spots......Page 88
Cords Galore......Page 90
Making Babies and Playing Roulette?......Page 92
What’s the Trigger?......Page 93
Paradox, or Grandma’s Wisdom?......Page 97
Journey’s End?......Page 100
Technical References......Page 107
4. A Child Psychologist’s Journey Jeanette van Dongen-Melman......Page 110
The Start of the Journey......Page 112
Becoming Aware of the Life-Threatening Nature of Leukaemia is a Process......Page 115
Dealing with Emotions Resulting from Leukaemia......Page 120
Misconceptions about Dealing with Emotions......Page 122
Reading the Child’s Behaviour and Responding to It......Page 123
Parents of Children with Leukaemia: Where do We Go from Here?......Page 124
Siblings: The Forgotten Children......Page 127
If a Child Dies......Page 131
All’s Well that Ends Well?......Page 132
Better or Worse Off by the Experience with Leukaemia?......Page 136
Alleviating Stressors......Page 138
Concluding Remarks......Page 143
General References......Page 144
Technical References......Page 145
5. A Mother’s Journey Nicola Horlick......Page 148
Recognition and Realisation......Page 164
Diagnosis......Page 169
Treatment......Page 171
Hair Loss and Havoc......Page 174
School Life......Page 177
Second Home......Page 180
My Best Friends: Freddie and the Infamous Emla Cream......Page 182
Mum, Dad and Hospital Life......Page 184
Cocktails, Jelly and Drugs......Page 185
Winning the Race......Page 187
Looking Forward......Page 189
A Family’s Journey: The Mother Delena Fernandes......Page 192
Diagnosis......Page 197
Guilt and Uncertainty......Page 199
Treatment: The Long Road......Page 200
Religious Belief: Challenges and Comfort......Page 204
Friends and Family......Page 205
Looking Back, Looking Forward......Page 206
Glossary of Terms......Page 210
Index......Page 214