Western biomedicine and Eastern therapeutics : an integrative strategy for personalized and preventive healthcare

Ch. 1. Evidence-based practice. 1.1. The FDA drug approval process. 1.2. Randomized controlled trial. 1.3. Level of evidence. 1.4. Cochrane review. 1.5. Drug development. 1.6. Translational medicine --
ch. 2. Modern western biomedicine. 2.1. ATP hydrolysis. 2.2. Oxidative phosphorylation, the electron transport chain, the Krebs cycle. 2.3. Glycolysis, aerobic respiration, the Warburg effect. 2.4. Reactive oxygen species, oxidative stress, redox signaling. 2.5. Cell metabolism. 2.6. The central dogma of molecular biology, the genome. 2.7. Eukaryotic cell division cycle. 2.8. Meiosis, Mendelian inheritance, genetic disorder. 2.9. Chromatin modification, complex disorder. 2.10. Immunity, hematopoiesis --
ch. 3. Traditional oriental ethnomedicine. 3.1. Ayurveda. 3.2. Asana, pranayama, dhyana. 3.3. Traditional Chinese medicine. 3.4. Acupuncture --
ch. 4. Integrative medicine. 4.1 Bioenergetics, tridosha, chronic disorder. 4.2 Complex adaptive system, yogic cognitive-behavioral practice, psychological stress management. 4.3 Placebo effect, acupuncture analgesia, chronic pain. 4.4 Periodontitis: an example of holistic therapy. 4.5 Practical clinical trial for the effectiveness of integrative therapy --
ch. 5. Safety and regulation of herbal products. 5.1. Plant secondary metabolites. 5.2. Pharmacodynamic and pharmacokinetic herb-drug interactions. 5.3. Regulation of TCM and other natural herbal products in China. 5.4. Kampo medicine in Japan. 5.5. Regulation of TCM medicine in Taiwan. 5.6. Regulation of natural health products in Canada. 5.7. Botanical products as dietary supplements in the United States. 5.8. Regulation of traditional herbal medicinal products in the European Union --
ch. 6. Cancer. 6.1. Six core and two emerging hallmarks of cancer. 6.2. Mechanisms of hallmark acquisition: genomic and epigenomic instability, inflammation
 microenvironment. 6.3. Frontiers of conventional treatment: drug cocktail cotargeting multiple hallmarks
 personalized targeted therapy. 6.4. TCM carbuncle-treating, TCM mediating formulas
 TCM cold herbs against neoplasms. 6.5. Uterine leiomyoma: Gui Zhi Fu Ling Wan and Yi Mu Cao. 6.6. Benign nonfibroid neoplasm of the uterus: Gui Zhi Fu Ling Wan and E Shu. 6.7. Benign neoplasm of the ovary: Gui Zhi Fu Ling Wan and Yi Mu Cao. 6.8. Benign neoplasm of the thyroid gland: San Zhong Kui Jian Tang and Xia Ku Cao. 6.9. Benign neoplasm of the breast: Jia Wei Xiao Yao San and Pu Gong Ying. 6.10. Lipoma: San Zhong Kui Jian Tang and Bai Jie Zi. 6.11. Benign neoplasm of male genital organs: Ji Sheng Shen Qi Wan and Che Qian Zi. 6.12. Benign neoplasm of the lower GI tract digestive system: Ban Xia Xie Xin Tang and Yan Hu Suo. 6.13. Carcinoma in situ of the breast and genitourinary system: Ji Sheng Shen Qi Wan and Pu Gong Ying. 6.14. Benign neoplasm of the brain and other parts of the nervous system: Zhen Ren Huo Ming Yin and Bei Mu. 6.15. Malignant neoplasm of the female breast: Jia Wei Xiao Yao San and Pu Gong Ying. 6.16. Malignant neoplasm of the liver and intrahepatic bile ducts: Jia Wei Xiao Yao San and Bai Hua She She Cao. 6.17. Malignant neoplasm of the nasopharynx: Gan Lu Yin and Xuan Shen. 6.18. Malignant neoplasm of the colon: Xiang Sha Liu Jun Zi Tang and Ban Zhi Lian. 6.19. Malignant neoplasm of the rectum and anus: Xiang Sha Liu Jun Zi Tang and Bai Hua She She Cao. 6.20. Malignant neoplasm of the trachea, bronchus and lung: Bai He Gu Jin Tang and Ban Zhi Lian. 6.21. Malignant neoplasm of the cervix uteri: Jia Wei Xiao Yao San and Bai Hua She She Cao. 6.22. Malignant neoplasm of the stomach: Ban Xia Xie Xin Tang and Ban Zhi Lian. 6.23. Malignant neoplasm of the prostate: Ji Sheng Shen Qi Wan and Huang Bai. 6.24. Malignant neoplasm of the ovary and other uterine adnexa: Gui Zhi Fu Ling Wan and Ban Zhi Lian. 6.25. Malignant neoplasm of the bladder: Ji Sheng Shen Qi Wan and Ban Zhi Lian. 6.26. Malignant neoplasm of the thyroid gland: Jia Wei Xiao Yao San and Xuan Shen. 6.27. Secondary malignant neoplasm of the respiratory and digestive systems: Chai Xian Tang and Mai Men Dong. 6.28. Malignant neoplasm of the mouth: Gan Lu Yin and Ban Zhi Lian. 6.29. Malignant neoplasm of the tongue: Gan Lu Yin and Dan Can. 6.30. Malignant neoplasm of the brain: Bu Yang Huan Wu Tang and Tian Ma. 6.31. Malignant neoplasm of lymphoid and histiocytic tissue: San Zhong Kui Jian Tang and Pu Gong Ying. 6.32. Malignant neoplasm of the kidney: Zhu Ling Tang and Ban Zhi Lian. 6.33. Malignant neoplasm of the esophagus: Bu Zhong Yi Qi Tang and Ban Zhi Lian. 6.34. Malignant neoplasm of other, ill-defined sites: Yang Yin Qing Fei Tang and Dan Can --
ch. 7. Common fatal diseases. 7.1. Atherosclerosis, hypertension, cerebrocardiorenal vascular disease. 7.2. Low-grade chronic inflammation, insulin resistance, metabolic syndrome. 7.3. Oligemic/hypoxic insults, blood-brain barrier breakdown, cerebrodegenerative disease. 7.4. Tobacco smoke, chronic obstructive pulmonary disease, tuberculosis. 7.5. Steatosis, alcohol, chronic liver disease and cirrhosis. 7.6. Pathophysiology-specific TCM formulas and herbs for the common fatal diseases. 7.7. Ischemic heart disease: Xue Fu Zhu Yu Tang and Dan Can. 7.8. Cerebrovascular disease: Bu Yang Huan Wu Tang and Dan Can. 7.9. Alzheimer's and other dementias: Tian Wang Bu Xin Dan and Yuan Zhi. 7.10. Hypertensive heart and renal disease: Tian Ma Gou Teng Yin and Dan Can. 7.11. Hypertensive heart disease: Tian Ma Gou Teng Yin and Dan Can. 7.12. Essential hypertension: Tian Ma Gou Teng Yin and Dan Can. 7.13. Atherosclerosis: Jia Wei Xiao Yao San and Dan Can. 7.14. Diabetes mellitus: Liu Wei Di Huang Wan and Tian Hua Fen. 7.15. Nephritis, nephrotic syndrome and nephrosis: Ji Sheng Shen Qi Wan and Che Qian Zi. 7.16. Chronic obstructive pulmonary disease: Ma Xing Gan Shi Tang and Bei Mu. 7.17. Acute bronchitis and bronchiolitis: Ma Xing Gan Shi Tang and Xing Ren. 7.18. Tuberculosis: Bai He Gu Jin Tang and Yu Xing Cao. 7.19. Pneumonia: Yin Qiao San and Yu Xing Cao. 7.20. Chronic liver disease and cirrhosis: Jia Wei Xiao Yao San and Yin Chen Hao. 7.21. Obesity and other hyperalimentation: Fang Feng Tong Sheng San and Shan Zha. 7.22. Diarrhea: Huo Xiang Zheng Qi San and Ge Gen --
ch. 8. Common nonfatal diseases. 8.1. Common cold, cough, allergic/chronic rhinitis. 8.2. Sleep disturbance, headache, palpitations, dizziness. 8.3. Arthralgia, cervicalgia, backache, lumbago, myalgia, fibromyalgia, neuralgia. 8.4. Constipation, dyspepsia, bloating, acute gastritis. 8.5 Chronic hepatitis, contact dermatitis. 8.6 Pharmacokinetics of TCM prescription by relative weighting of the ingredients. 8.7. The common cold: Yin Qiao San and Jie Geng. 8.8. Cough: Ma Xing Gan Shi Tang and Jie Geng. 8.9. Allergic rhinitis: Xin Yi Qing Fei Tang and Chan Tui. 8.10. Chronic rhinitis: Xin Yi Qing Fei Tang and Yu Xing Cao. 8.11. Joint pain: Shu Jing Huo Xue Tang and Yan Hu Suo. 8.12. Lumbago: Du Huo Ji Sheng Tang and Du Zhong. 8.13. Myalgia and myositis, fibromyositis: Shu Jing Huo Xue Tang and Yan Hu Suo. 8.14. Neuralgia, neuritis and radiculitis: Shu Jing Huo Xue Tang and Yan Hu Suo. 8.15. Backache: Shu Jing Huo Xue Tang and Yan Hu Suo. 8.16. Cervicalgia: Ge Gen Tang and Ge Gen. 8.17. Sleep disturbance: Suan Zao Ren Tang and Ye Jiao Teng. 8.18. Constipation: Ma Zi Ren Wan and Da Huang. 8.19. Contact dermatitis: Xiao Feng San and Lian Qiao. 8.20. Chronic hepatitis: Jia Wei Xiao Yao San and Yin Chen Hao. 8.21. Headache: Chuan Xiong Cha Diao San and Ge Gen. 8.22. Palpitations: Zhi Gan Cao Tang and Dan Can. 8.23. Dizziness/vertigo: Ling Gui Zhu Gan Tang and Dan Can. 8.24. Functional dyspepsia: Ban Xia Xie Xin Tang and Hai Piao Shao. 8.25. Gas/bloating: Ban Xia Xie Xin Tang and Hai Piao Shao. 8.26. Acute gastritis: Ban Xia Xie Xin Tang and Hai Piao Shao --
ch. 9. Condition of the reproductive system. 9.1. Menstruation, premenstrual syndrome, menopause, osteoporosis. 9.2. Male/female infertility, male organic/psychogenic impotence. 9.3. TCM gynecologic and TCM tonifying formulas for menstrual disorders and male impotence. 9.4. Dysmenorrhea: Dang Gui Shao Yao San and Yan Hu Suo. 9.5. Premenstrual tension syndrome: Jia Wei Xiao Yao San and Yi Mu Cao. 9.6. Absence of menstruation: Jia Wei Xiao Yao San and Yi Mu Cao. 9.7. Scanty or infrequent menstruation: Jia Wei Xiao Yao San and Yi Mu Cao. 9.8. Excessive or frequent menstruation: Xiong Gui Jiao Ai Tang and Xian He Cao. 9.9. Irregular menstruation: Jia Wei Xiao Yao San and Yi Mu Cao. 9.10. Other/unspecified disorders of menstruation: Jia Wei Xiao Yao San and Yi Mu Cao. 9.11. Menopausal state: Jia Wei Xiao Yao San and Suan Zao Ren. 9.12. Unspecified (post) menopausal disorder: Jia Wei Xiao Yao San and Suan Zao Ren. 9.13. Leukorrhea: Wan Dai Tang and Tu Fu Ling. 9.14. Osteoporosis: Du Huo Ji Sheng Tang and Du Zhong. 9.15. Female infertility (unspecified origin): Shen Ling Bai Zhu San and Tu Si Zi. 9.16. Male infertility (unspecified origin): Huan Shao Dan and Yin Yang Huo. 9.17. Impotence (organic): Huan Shao Dan and Yin Yang Huo. 9.18. Impotence (psychosexual dysfunction): Huan Shao Dan and Yin Yang Huo --
ch. 10. Theories of aging. 10.1. Oxidative stress theory of aging. 10.2. Telomere and mitochondrial theories of aging. 10.3. Immunosenescence theory of aging. 10.4. Endocrine theory of aging. 10.5. Ayurvedic theory of aging. 10.6. TCM theories of aging --
ch. 11. Regenerative medicine. 11.1. Adult stem cells, tissue homeostasis. 11.2. De/transdifferentiation, reprogramming, in vivo and in vitro regenerative therapy. 11.3. Hematopoietic stem cells, multipotent stromal cells, bone marrow. 11.4. Irreversible and reversible factors in adult stem cell aging. 11.5. Stem cell niche, mechanotransduction, axial-skeletal flexing yoga asanas, acupressure. 11.6. Seasonal tonifying herbal regimens, personalized preventive medicine, adult stem cell rejuvenation --
ch. 12. Longevity. 12.1. Moderate physical activity, anti-inflammation, neural plasticity. 12.2. Calorie restriction, alternate-day fasting, mitochondrial hormesis. 12.3. Circadian rhythms, sleep-wake cycle, energy homeostasis. 12.4. Mindfulness meditation: a mental workout for reduction of perceived stress. 12.5. Tai Chi: a combination of aerobic exercise, resistance training and mindfulness meditation. 12.6. The Mediterranean diet, herbs and spices, organic foods. 12.7. Self-assembly principle, TCM fire-purging diet, personalized anti-inflammatory regimens. 12.8. Social integration, brain aging reversal, longevity.