Viral epidemics: from influenza to ebola and COVID-19 /

Cover
Half Title
Title Page
Copyright Page
Dedication
Table of contents
Figures
Preface
Acknowledgments
1 A Brief Introduction to Virology
Preventing the Unknown
	At Long Last: Virus Visualization
	Molecular Genetics
	Identifying the Evolutionary History of Viruses
	The Infinite – and Infinitely Powerful – Virosphere
	References
2 The Smallpox Story: Gone but not Forgotten
	The Smallpox Story: Gone but not Forgotten
		The Disease
		Edward Jenner and the Development of Smallpox Vaccine
	The Virus
	Smallpox Eradication
	The Post-Eradication Era: Smallpox as a Biological Weapon
	9-11-2001
	Looking Back :: Moving Forward
	Historic Perspective
		Vaccination: Race and Religion
	References
	Bibliography
3 Yellow Fever: The Jungle Story
	Yellow Fever: The Jungle Story
	The Disease
	The Vector
	Epidemiology of Yellow Fever
	The Vaccine
	The Virus
	Public Health Management of Yellow Fever
	Looking Back :: Moving Forward
	Historic Perspective: Yellow Fever as an Agent of Colonialism
	References
	Bibliography
4 The Great Influenza: A Virus for All Time
	The Great Influenza: A Virus for All Time
	The Disease
	The Great Influenza: The Global Influenza Pandemic of 1918
	The Virus: The Long Road to Discovery
	Return of the Canada Goose
	Global Influenza Pandemics After 1918
	The Vaccine
	Finally – Identification of the 1918 Pandemic Flu Virus
	Influenza Treatment
	The Threat of Pandemic Avian Flu
	Canada Geese Again
	Looking Back :: Moving Forward
	Historic Perspective: Influenza and the Public Health Movement
	References
	Bibliography
5 Polio: The Plague of Summer
	Polio: The Plague of Summer
	The Disease: A Chronology of Discovery
	Polio and FDR
	The Disease: Epidemiology and Pathophysiology Defined
	Treatment and Recovery
	At Last – Progress in Polio Research
	Polio Prevention: Development of Polio Vaccines
	The Poliovirus
	Global Polio: The Challenge
	Post-Polio Syndrome
	Looking Back :: Moving Forward
	Historic Perspective: Race and Class in the Time of Polio
	Historic Perspective: Physical Disability Before Polio
	References
	Bibliography
6 HIV and AIDS: The Never-Ending Story
	HIV and AIDS: The Never-Ending Story
	Discovery of the Human Immunodeficiency Virus
	The Virus
	The Disease: HIV Infection and the Acquired Immune Deficiency Syndrome
	Testing for HIV Infection
	Prevention, Treatment and Treatment as Prevention: USA
		I. Prevention
		II. Treatment
	Treatment as Prevention
	Evolving Epidemiology of HIV/AIDS in the United States: Implementation of Prevention and Treatment Advances
		Sexual Transmission: Gay and Bisexual Men
		HIV/AIDS in Women
		Injection Drug Use
		Transfusion of HIV-Contaminated Blood and Blood Products
		Maternal–Infant Transmission of HIV: Babies with HIV/AIDS
	HIV Infection/AIDS in the USA: Current Statistics (2016–2019)
	Global HIV/AIDS
		History of Global Spread
	Origin of HIV
	The Pattern of Global Spread
	The Evolving Global Epidemiology of HIV Infection and AIDS: Implementation of Prevention and Treatment Advances
		Sexual Transmission of HIV
			Gay and Bisexual Men (MSM); Female Partners of HIV(+) Men
		Injection Drug Users (IDU)
		Global Perinatal Infection
	HIV/AIDS Prevention and Treatment: Global Status
	Looking Back :: Moving Forward
	Historic Perspective: The Power of Activism
	References
	Bibliography
7 Out of Nowhere: West Nile Virus, SARS, Zika, and Ebola
	A Hopeful Ebola Warrior
	Out of Nowhere: West Nile Virus, SARS, Zika, and Ebola
		I. West Nile Virus
			The Disease and the Vector Identified
			The Virus, the Reservoir, and the Vector
			The Disease, Updated
			Diagnosis, Treatment, and Prevention
			After NYC
			Looking Back :: Moving Forward
		II. Severe Acute Respiratory Syndrome – SARS
			The Virus
			Looking Back :: Moving Forward
		III. ZIKA Virus
			The Virus
			And Then – Out of Nowhere
			Epidemic Spread
			Prevention
	Looking Back :: Moving Forward
		IV. Ebola
			The Virus
			2014: And Then, Out of Nowhere …
			Global Pandemic Averted
			Identifying the Outbreak Source
			Looking Back :: Moving Forward
			Update
	Out of Nowhere?
	References
8 A Way Forward:
	A Way Forward
	A Way Forward
	Option Two: Epidemiologic Analysis of Viral Epidemics of the Last Century
		I. Constant Vigilance: Current Status
			Constant Vigilance: Progress/Potential
		II. Know Your Enemy: Current Status
			Know Your Enemy: Progress/Potential
		III. The Homefield Advantage: Healthcare Infrastructure and Community Involvement for Epidemic Preparedness – Current Status
			The Homefield Advantage: healthcare infrastructure and Community Involvement for Epidemic Preparedness – Progress/Potential
		IV. Bring Your Checkbook: Current Status
			Bring Your Checkbook: Progress/Potential
	Looking Back :: Moving Forward
	References
	Bibliography
9 And Now, as Promised: The 2019 SARS-CoV-2/COVID-19 Pandemic
	The 2019-nCoV/SARS-CoV-2 Pandemic
	The Virus
	The Disease
	Diagnosis
	Treatment
	Prevention/Vaccine Development
	Epidemic Response: China
	Epidemic Response: International
	Mid-February Assessment
	Emerging Epidemiologic, Virologic, and Clinicopathologic Picture
	February 14 to February 28, 2020
	Looking Back :: Moving Forward
	References
Epilogue
Index