Vasopeptides: Chemistry, Pharmacology, and Pathophysiology

Front Matter....Pages i-xxiv
Front Matter....Pages 1-1
Hydroxyproline Analogs of Bradykinin: Biological Activities and Solution Structures....Pages 3-8
Ion Binding by Macrocyclic Depsipeptide Antibiotics: Mutual Replaceability of Amide and Ester Groups....Pages 9-21
Radioimmunoassay of Circulating Blood Kinin Levels....Pages 23-32
Some Properties of Bovine High Molecular Weight Kininogen....Pages 33-41
Bradykininogen Synthesis by Liver....Pages 43-47
Characteristics of Spontaneous Formation of Vasopressor Principle (VA) and of Plasma Kinin as Revealed by Temperature Changes....Pages 49-56
Plasma Kininogen Assay. Importance of Maintaining Blood at Body Temperature until Assay....Pages 57-59
Guinea Pig Prekallikrein Activator....Pages 61-69
The Kallikrein-Like Activity Present in Human Euglobulin Fraction....Pages 71-75
Protein Components which Relate to the Kinin Releasing System in Bovine Plasma....Pages 77-86
The Presence of a Smooth Muscle Contracting and Bradykinin Potentiating Factor in Plasma....Pages 87-90
Observations on the Chymotrypsin Peptide Releasing Activity on Plasmas....Pages 91-102
An Alternative Scheme of Kinin Formation during Contact Activation of Human Plasma....Pages 103-108
The Relationship between the Plasma Kinin-System and the Contact Phase of Blood-Coagulation in Man....Pages 109-118
Connections between Kinin Formation and Complement....Pages 119-127
The Role of Plasmin in the Activation of the Kinin System....Pages 129-134
Clinical Determination of the Kallikrein in Human Urine....Pages 135-139
Dissociation of Oedema Provoking Factor of Agkistrodon Piscivorus Venom from Kininogenase....Pages 141-148
Identity of Kininase II with an Angiotensin I Converting Enzyme....Pages 149-153
Inhibition by Sulfhydryl Reagents of the Effects of Bradykinin, Arachidonic Acid and “Slow Reacting Substance C”....Pages 155-166
Front Matter....Pages 1-1
Studies on Kinin-Forming Enzymes in Human Plasma and their Heterogeneity....Pages 167-184
Front Matter....Pages 185-185
Structure-Activity Relationships of Neurohypophyseal Polypeptides on Different Types of Isolated Mammalian Blood Vessels....Pages 187-196
Participation of Kinins in the Regulation of Cerebral Vasopermeability....Pages 197-208
Influence of the Autonomic Nervous System on Fibrinolytic Activity Caused by Bradykinin....Pages 209-220
Fine Structure of Secretory Granules in Mammalian Submaxillary Glands....Pages 221-231
Distribution of Kallikrein, Trypsin-Like Proteases and Amylase in Submaxillary Glands....Pages 233-238
Changes in Kallikrein Activity of Rat Submandibular Gland during Post-Natal Development....Pages 239-250
Effect of Bradykinin Potentiating Peptide on Coronary Circulation in Conscious Dogs....Pages 251-257
Metabolic Fates of Bradykinin, Angiotensin I, Adenine Nucleotides and Prostaglandins E 1 and F 1α in the Pulmonary Circulation....Pages 259-265
Pulmonary Endothelial Cells and the Metabolism of Adenine. Nucleotides, Kinins and Angiotensin I....Pages 267-276
Bronchial Motility Regulation and Bradykinin....Pages 277-283
The Action of Bradykinin on Artero-Venous Hyperstomia in Man....Pages 285-288
Rat Intestinal Kallikrein....Pages 289-296
Guinea Pig Kininogen-Kinin System in Pregnancy and under Hormonal Influence....Pages 297-308
Comparative Actions of Kinins of Increasing Molecular Weight on Smooth Muscle, Blood Pressure and Vascular Permeability....Pages 309-316
Effect of Kinins and of Kinin-Releasing Enzymes on Rat Mast Cells....Pages 317-323
The Problem of Latency at Bradykinin and Some Analogues....Pages 325-330
Supplemental Investigations to the Kinin Potentiating Action of Some Local Anesthetics....Pages 331-336
Comparative Action of Peptides on the Gall Bladder and the Sphincter of Oddi....Pages 337-346
Inhibitory Activity of Glucagon on Caerulein Exocrine Stimulation, Independent of Hyperglycemia....Pages 347-355
Front Matter....Pages 185-185
Bradykinin Antagonism by Biflavonyls from Ginkgo Biloba L. and Cupressus Torulosa....Pages 357-360
Front Matter....Pages 361-361
Plasma Kininogen and Arteriovenous Ratio in Late Pregnancy Toxemia....Pages 363-365
Fetal Distress and Plasma Kininogen in the Newborn....Pages 367-370
Changes in Kininogen Content of Serum and Some Organs during Injury and Inflammation in Rats....Pages 371-379
Studies on the Mechanism of Kinin Release Induced by Antilymphocyte Globulin....Pages 381-390
Activation of Bradykinin System in Acute Inflammation Induced by Endogenous or Exogenous Amines....Pages 391-398
A Structure-Activity Basis for Vasotropic Peptide Therapy in Shock....Pages 399-408
Bradykinin Metabolism in Shock and in State of Shock-Resistance....Pages 409-416
Acid Dependent Kinin-Forming System in Mammalian Malignant and Normal Tissue....Pages 417-434
Role of Vasoactive Peptides and Local Hormones in Experimental Cold Injury in Monkeys....Pages 435-443
Prekallikrein and Kallikrein Inhibitor in Plasma of Patients Affected by Recent Myocardial Infarction....Pages 445-452
Plasmatic Kininogen in Acute Hepatitis and in Liver Cirrhosis....Pages 453-456
Kallikrein on Arterial Hypertension:1. Kallikrein-Like Activity in the Urine of Figure-in-Eight Ligature in one Kidney....Pages 457-475
The Effects of Bradykinin on Single Ranvier Node of Nerve Fibres in the Frog....Pages 477-482
Release of Serotonin in Man Induced by Some Polypeptides....Pages 483-485
Back Matter....Pages 487-495