Tyrosine Phosphorylation/Dephosphorylation and Downstream Signalling

Front Matter....Pages I-XI
Front Matter....Pages 1-1
Protein Tyrosine Phosphorylation-Dephosphorylation and Cell Signaling....Pages 3-9
Regulation and Functions of Src-Family Kinases: An Update....Pages 11-30
Mitogen-Activated Signalling Pathways....Pages 31-44
Studies of the very Early Responses of a Receptor Tyrosine Kinase to Growth Factor Binding and their Application to the Purification and Identification of Proteins that are Tyrosine Phosphorylated in the Growth Factor Response....Pages 45-62
The Role of P21 ras in Cell Signalling....Pages 63-68
The HGF/SF Receptor Kinase: Structure and Function....Pages 69-85
RET/ptc and TRK Oncogenes in Papillary Thyroid Carcinoma....Pages 87-98
Structure-Function Analysis of Hepatocyte Growth Factor and its Tyrosine-Kinase Receptor c-Met....Pages 99-102
Oncogenic Activation of the Met/HGF Receptor Tyrosine Kinase is Promoted by Leucine Zipper Mediated Dimerization....Pages 103-106
Specificity of the Truncated Form of Human T-cell Protein Tyrosine Phosphatase toward Phosphorylated Synthetic Peptides....Pages 107-110
Regulation of Tyrosine Protein Phosphatases by Binding to Phospholipids and Covalent Modification....Pages 111-114
Localization-Dependent Regulation of Lymphocyte Tyrosine Phosphatases....Pages 115-118
Protein Tyrosine Phosphatases in the Nematode Ascaris Suum ....Pages 119-122
Non-radioactive determination of phosphotyrosine phosphatase (PTPase) activity....Pages 123-126
New Protein Tyrosine Phosphatases from Vascular Smooth Muscle Cells: Transcript Levels in Tissues and in Cultured Cells....Pages 127-130
Recombinant CSK Expressed in E.Coli is Phosphorylated on Tyrosine Residue(s) and Undergoes in Vitro Phosphorylation....Pages 131-134
Polylysine Activates a Splenic Tyrosine Protein Kinase Encoded by the fgr Protooncogene....Pages 135-138
Protein Phosphorylation in the Signal Transduction of the Neuropeptide Bombesin in Swiss 3T3 Cells....Pages 139-142
Growth Hormone (GH) Increases Lipoprotein Lipase mRNA in Cells Transfected with the Rat GH Receptor cDNA....Pages 143-146
Front Matter....Pages 147-147
Role of Phosphatidylinositol 3-Kinase in Growth Factor and Oncogene Signaling....Pages 149-165
Front Matter....Pages 147-147
Isolation and Characterization of Phosphatidylinositol 4-Kinase Isoenzymes from Bovine Brain....Pages 167-170
Determination of Phosphoinositides and Inositol Phosphates. Principles and Rules....Pages 171-192
Phosphoinositides in Rabbit Skeletal Muscle Membranes....Pages 193-196
Renaturation of Phosphatidylinositol 4- and Phosphatidylinositol 4-Phosphate 5′-Kinases Following Polyacrylamide Gelelectrophoresis in Presence of SDS. Studies on their Substrate Binding Requirements Using Synthetic Substrate Analogues....Pages 197-200
Front Matter....Pages 201-201
The Catalytic Subunit of cAMP-Dependent Protein Kinase....Pages 203-213
Casein Kinase I and the Classification of Protein Kinases: What’s in a Name?....Pages 215-222
Downregulation of protein kinase C is associated with phenotypic changes and enhanced proliferation of vascular smooth muscle cells....Pages 223-226
Insulin-Stimulated Seryl/Threonyl Protein Kinases in Diabetic Rats and the Effects of Vanadium Treatment....Pages 227-230
Protein Phosphorylation in Prokaryotes — Evidence for PKC-Like Activities in Escherichia Coli ....Pages 231-234
Phosphorylation of Creatine Kinase in Myogenic Cells: Effects of Okadaic Acid and other Agents Affecting Cellular Protein Phosphorylation....Pages 235-240
Non-Radioactive Determination of Phosphoamino Acids by Capillary Electrophoresis....Pages 241-246
Characterization of Phosphoproteins by 31 P-NMR Spectroscopy....Pages 247-257
CK-2, a Multifunctional Protein Kinase and its Role during Proliferation....Pages 259-262
Front Matter....Pages 263-263
Molecular Complexity of Protein Phosphatase 2A Holoenzymes and Delineation of their Function....Pages 265-286
Dephosphorylation in Vitro Inhibits Ligand and DNA Binding Activities of Human Estrogen Receptor....Pages 287-290
Characterization of Novel Nuclear Inhibitors of Protein Phosphatase — 1....Pages 291-295
Front Matter....Pages 297-297
The Mitogen-Activated p70 s6k / p85 s6k ....Pages 299-309
Expression of the p70 s6k / p85 s6k Isoforms from a Single Gene and Activation Following Mitogenic Stimulation....Pages 311-316
Control of S6 phosphorylation in normal and v-src transformed cells....Pages 317-320
The Phosphorylated Ribosomal Protein in Tetrahymena is Homologous with Mammalian Ribosomal Protein S4....Pages 321-324
Front Matter....Pages 297-297
Nucleocytoplasmic Transport of Ribosomal Protein S6....Pages 325-328
Front Matter....Pages 329-329
Regulating the G 2 Checkpoint in the Cell Cycle....Pages 331-341
CD2-Dependence on the CD3-Zeta-Chain in T Cell Signalling — Shown by Inhibitory and Modifying Effects of Cholera Toxin....Pages 343-346
cdc25 protein phosphatase in mammalian fibroblasts: cell cycle expression and intracellular localization....Pages 347-350
Front Matter....Pages 351-351
The Role of Small Molecular Weight GTP-Binding Proteins in Stimulus Secretion Coupling of Pancreatic Acinar Cells....Pages 353-367
Characterization of Calcium Transport ATPase Isozymes in Different Blood Cells....Pages 369-372
Back Matter....Pages 373-380