Treatment of Dry Skin Syndrome: The Art and Science of Moisturizers

Front Matter....Pages i-xxxvii
Front Matter....Pages 1-1
Moisturizers as Cosmetics, Medicines, or Medical Device? The Regulatory Demands in the European Union....Pages 3-16
Design of Claims Support for Moisturizers....Pages 17-25
Educational Interventions for the Management of Children with Dry Skin....Pages 27-39
Dry Skin in Childhood and the Misery of Eczema and Its Treatments....Pages 41-58
Use of Moisturizers in Patients with Atopic Dermatitis....Pages 59-73
Front Matter....Pages 75-75
Sensory Systems of Epidermal Keratinocytes....Pages 77-94
Sensitive Skin: Intrinsic and Extrinsic Contributors....Pages 95-109
Electron Tomography of Skin....Pages 111-117
Filaggrin Gene Defects and Dry Skin Barrier Function....Pages 119-124
Molecular Organization of the Lipid Matrix in Stratum Corneum and Its Relevance for the Protective Functions of Human Skin....Pages 125-147
Desquamation: It Is Almost All About Proteases....Pages 149-178
Endogenous Retroviral-Like Aspartic Protease, SASPase as a Key Modulator of Skin Moisturization....Pages 179-192
Vernix Caseosa and Its Substitutes: Lipid Composition and Physicochemical Properties....Pages 193-213
The Role of Tight Junctions and Aquaporins in Skin Dryness....Pages 215-232
Biomechanics of the Barrier Function of Human Stratum Corneum....Pages 233-254
Front Matter....Pages 255-255
Update on Atopic Eczema with Special Focus on Dryness and the Impact of Moisturizers....Pages 257-267
Update on Hand Eczema with Special Focus on the Impact of Moisturisers....Pages 269-278
Update on Ichthyosis with Special Emphasis on Dryness and the Impact of Moisturizers....Pages 279-284
Psoriasis and Dry Skin: The Impact of Moisturizers....Pages 285-293
Update on Infant Skin with Special Focus on Dryness and the Impact of Moisturizers....Pages 295-310
Front Matter....Pages 311-311
The Composition and Development of Moisturizers....Pages 313-339
Ungual Formulations: Topical Treatment of Nail Diseases....Pages 341-354
Preservation of Moisturisers....Pages 355-366
Potential Allergens in Moisturizing Creams....Pages 367-378
Formulating Moisturizers Using Natural Raw Materials....Pages 379-397
Chemical and Physical Properties of Emollients....Pages 399-417
Polyfunctional Vehicles by the Use of Vegetable Oils....Pages 419-429
The Effect of Natural Moisturizing Factors on the Interaction Between Water Molecules and Keratin....Pages 431-439
Impact of Stratum Corneum Damage on Natural Moisturizing Factor (NMF) in the Skin....Pages 441-451
Water and Minerals in the Treatment of Dryness....Pages 453-458
Hyaluronan Inside and Outside of Skin....Pages 459-471
Glycerol as a Skin Barrier Influencing Humectant....Pages 473-480
The Use of Urea in the Treatment of Dry Skin....Pages 481-492
Urea and Skin: A Well-Known Molecule Revisited....Pages 493-501
The Influence of Climate on the Treatment of Dry Skin with Moisturizer....Pages 503-511
Emollient Therapy and Skin Barrier Function....Pages 513-523
Skin Barrier Responses to Moisturizers: Functional and Biochemical Changes....Pages 525-544
Changes in Stratum Corneum Thickness, Water Gradients and Hydration by Moisturizers....Pages 545-560
Skin Moisture and Heat Transfer....Pages 561-580
Back Matter....Pages 581-591