Transport Phenomena in the Nervous System: Physiological and Pathological Aspects

Front Matter....Pages i-xxii
Front Matter....Pages 1-1
Metabolite Transport at Cell Membranes....Pages 3-12
Possible Role of Glutathione in Transport Processes....Pages 13-28
Front Matter....Pages 29-29
Transport Mechanisms in the Cerebrospinal Fluid System for Removal of Acid Metabolites from Developing Brain....Pages 31-40
The Morphological Approach to the Study of Normal and Abnormal Brain Permeability....Pages 41-54
The Transport of Metabolizable Substances into the Living Brain....Pages 55-75
The Specificity of Amino Acid and Sugar Carriers in the Capillaries of the Dog Brain Studied in Vivo by Rapid Indicator Dilution....Pages 77-87
Possible Role of Insulin in the Transport of Tyrosine and Tryptophan from Blood to Brain....Pages 89-94
The Influence of Liver-Bypass on Transport and Compartmentation In Vivo ....Pages 95-102
Certain Aspects of Drug Distribution to Brain....Pages 103-109
Penetration of Proteins in the Central Nervous System....Pages 111-129
Front Matter....Pages 131-131
The Characteristics of Glucose Transport Across the Blood Brain Barrier and its Relation to Cerebral Glucose Metabolism....Pages 133-149
Mechanisms for the Passive Regulation of Extracellular K + in the Central Nervous System: The Implications of Invertebrate Studies....Pages 151-164
Amino Acid Transport in Spinal and Sympathetic Ganglia....Pages 165-178
Uptake of Neurotransmitters and Precursors by Clonal Cell Lines of Neural Origin....Pages 179-198
On the Uptake Mechanism of Choline in Nerve Cell Cultures....Pages 199-209
The Uptake and Release of γ-Aminobutyric Acid (GABA) by the Retina....Pages 211-220
Amino Acid Transport in Isolated Neurons and Glia....Pages 221-236
Transport of Taurine in the Central Nervous System....Pages 237-252
Transport of Adenine Derivatives in Tissues of the Brain....Pages 253-264
Kinetical Analysis of the Uptake of Glucose Analogs by Rat Brain Cortex Slices from Normal and Ischemic Brain....Pages 265-272
Front Matter....Pages 131-131
Uptake and Exchange of GABA and Glutamate in Isolated Nerve Endings....Pages 273-289
Mechanisms of Transport for the Uptake and Release of Biogenic Amines in Nerve Endings....Pages 291-305
Characteristics of the Uptake and Release of Glutamic Acid in Synaptosomes from Rat Cerebral Cortex. Effects of Ouabain....Pages 307-317
Release of Biogenic Amines from Isolated Nerve Endings....Pages 319-335
Transport of Dopamine in Discrete Areas of the Striatum and of Cerebral Cortex in the Rat....Pages 337-345
Front Matter....Pages 237-237
Energetics of Low Affinity Amino Acid Transport into Brain Slices....Pages 349-370
Potassium Effects on Transport of Amino Acids, Inorganic Ions, and Water: Ontogenetic and Quantitative Differences....Pages 371-383
Evidence for A Synthesis-Dependent Release of GABA....Pages 385-394
Transport of Amino Acids and Catecholamines in Relation to Metabolism and Transmission....Pages 395-404
Changes in Cerebral Amino Acid Transport During Development....Pages 405-411
Front Matter....Pages 413-413
The Usefulness of Studies In Vitro for Understanding Cerebral Metabolite Transport In Vivo ....Pages 415-434
Release of Amino Acids from the Spinal Cord in Vitro and in Vivo....Pages 435-446
The Distribution of Drugs in the Central Nervous Sytem....Pages 447-461
Front Matter....Pages 463-463
Cerebral Permeability Phenomena in Epilepsy....Pages 465-477
Pathological Aspects of Brain Transport Phenomena....Pages 479-495
Brain Damage and Oral Intake of Certain Amino Acids....Pages 497-506
Physiopathology of the Blood-Brain Barrier....Pages 507-516
Brain Barrier Pathology in Acute Arterial Hypertension....Pages 517-527
Back Matter....Pages 529-541