Translational control of gene expression

COVER......Page 1
FRONT......Page 4
CONTENTS......Page 6
PREFACE......Page 10
1 Origin and principles of translational control......Page 12
2 Initiation of protein synthesis......Page 43
3 The elongation cycle......Page 99
4 Initiation site selection mechanisms......Page 136
5 Initiator binding to ribosomes......Page 195
6 Ribosomal recruitment......Page 254
7 Translational control of development......Page 303
8 Viral translational strategies......Page 379
9 Ribosomal subunit joining......Page 433
10 Cap-tail interactions......Page 454
11 Termination......Page 473
12 Genetic approaches to initiation in yeast......Page 492
13 PKR......Page 508
14 eIF2alpha kinase......Page 533
15 PERK in the ER......Page 551
16 Amino acid regulation of initiation......Page 565
17 Translational control during heat shock......Page 584
18 Translational control of uORFs......Page 599
19 IRES and their investigation......Page 619
20 Translational control and cancer......Page 640
21 Translational control of ferritin synthesis......Page 658
22 Translational control of TOP mRNAs......Page 674
23 S6 phosphorylation......Page 697
24 Control of elongation......Page 720
25 Programmed frameshifting, hopping, readthrough......Page 741
26 Recoding UGA......Page 762
27 Polyadenylation-induced translation......Page 783
28 Interaction of translation and mRNA degradation in yeast......Page 804
29 Destabilization of nonsense in yeast......Page 823
30 NMD in mammals......Page 844
31 Translation initiation on picornavirus RNA......Page 864
32 Adenovirus inhibition of translation......Page 896
33 Reovirus translational control......Page 910
34 Translational reprogramming during infection......Page 928
35 Translational control in poxvirus infection......Page 946
36 Nontranslational functions......Page 967
INDEX......Page 992