Transcription factors in the nervous system : development, brain function and diseases

Front......Page 1
Contents......Page 6
Preface......Page 18
List of Contributors......Page 21
Color Plates......Page 25
Part I - Transcription Factors in Neural Development......Page 60
1 Roles of Hes bHLH Factors in Neural Development......Page 61
2 The Role of Pax6 in the Nervous System during Development and in Adulthood: Master Control Regulator or Modular Function?......Page 81
3 Phox2a and Phox2b: Essential Transcription Factors for Neuron Specification and Differentiation......Page 110
4 Functions of LIM-Homeodomain Proteins in the Development of the Nervous System......Page 131
5 The Roles of Serum Response Factor (SRF) in Development and Function of the Brain......Page 151
6 RE–1 Silencing Transcription Factor (REST): Regulation of Neuronal Gene Expression via Modification of the Chromatin Structure......Page 168
7 Roles of Tlx1 and Tlx3 and Neuronal Activity in Controlling Glutamatergic over GABAergic Cell Fates......Page 184
8 Transcriptional Control of the Development of Central Serotonergic Neurons......Page 198
9 Role of Nkx Homeodomain Factors in the Specification and Differentiation of Motor Neurons and Oligodendrocytes......Page 217
10 Sox Transcription Factors in Neural Development......Page 235
Part II - Transcription Factors in Brain Function......Page 258
11 The Role of CREB and CBP in Brain Function......Page 259
12 CCAAT Enhancer Binding Proteins in the Nervous System: Their Role in Development, Differentiation, Long-Term Synaptic Plasticity, and Memory......Page 294
13 The Role of c-Jun in Brain Function......Page 310
14 Expression, Function, and Regulation of Transcription Factor MEF2 in Neurons......Page 335
15 RORa: An Orphan that Staggers the Mind......Page 356
16 The Role of NF-kB in Brain Function......Page 375
17 Calcineurin/NFAT Signaling in Development and Function of the Nervous System......Page 401
18 Stimulus-Transcription Coupling in the Nervous System: The Zinc Finger Protein Egr–1......Page 427
Part III - Transcription Factors in Neuronal Diseases......Page 444
19 The Presenilin/g-Secretase Complex Regulates Production of Transcriptional Factors: Effects of FAD Mutations......Page 445
20 Transcriptional Abnormalities in Huntington’s Disease......Page 463
Index......Page 487