Trafficking Inside Cells: Pathways, Mechanisms and Regulation (Molecular Biology Intelligence Unit)

Front Matter....Pages i-xxi
Front Matter....Pages 1-1
Overview of Intracellular Compartments and Trafficking Pathways....Pages 3-14
How We Study Protein Transport....Pages 15-41
The Golgi Apparatus....Pages 42-66
The Endocytic Pathway....Pages 67-83
Regulated Secretion....Pages 84-102
Front Matter....Pages 103-103
Overview of Protein Trafficking Mechanisms....Pages 105-118
Entry into the Endoplasmic Reticulum: Protein Translocation, Folding and Quality Control....Pages 119-142
COP-Mediated Vesicle Transport....Pages 143-158
Clathrin-Mediated Endocytosis....Pages 159-182
Biogenesis of Dense-Core Secretory Granules....Pages 183-209
Lipid-Dependent Membrane Remodelling in Protein Trafficking....Pages 210-232
Carrier Motility....Pages 233-253
Tethering Factors....Pages 254-281
Intracellular Membrane Fusion....Pages 282-325
Front Matter....Pages 327-327
Regulation and Coordination of Intracellular Trafficking: An Overview....Pages 329-341
Regulation of Protein Trafficking by GTP-Binding Proteins....Pages 342-362
Posttranslational Control of Protein Trafficking in the Post-Golgi Secretory and Endocytic Pathway....Pages 363-387
Actin Doesn’t Do the Locomotion: Secretion Drives Cell Polarization....Pages 388-404
Intracellular Trafficking and Signaling: The Role of Endocytic Rab GTPase....Pages 405-418
The Exocytic Pathway and Development....Pages 419-438
Back Matter....Pages 439-445