Thyroid Cancer in Clinical Practice

Cover Page......Page 1
Title Page......Page 3
ISBN 1846285445......Page 4
Dedication Page......Page 5
Table of Contents......Page 7
Preface......Page 6
Epidemiology of Thyroid Cancer......Page 8
Terms and Definitions Related to Radiation, Radiation Doses, and Exposure......Page 10
Radionuclides of Iodine......Page 12
Medical Diagnostic Procedures from Internal Radiation......Page 13
Medical Therapeutic Procedures Using External Radiation......Page 14
Occupational Exposure in Nuclear Power Plant Workers......Page 15
Accidental Exposure to Atomic Bomb......Page 16
Prophylaxis for Radioactive Fallout......Page 17
Genetic Mutations as a Cause of Thyroid Cancer......Page 18
Familial Nonmedullary Thyroid Cancer......Page 19
Geographic Factors......Page 20
References......Page 21
Embryology......Page 24
Surgical Anatomy......Page 25
The Sodium Iodide Symporter......Page 26
Effects of Thyroid Hormones on the Individual......Page 29
Pituitary and Thyroid-Stimulating Hormone......Page 30
TSH Receptor......Page 31
References......Page 32
Diagnostic Testing......Page 34
Thyroid Scintigraphy......Page 36
Thyroid Ultrasound......Page 37
Treatment of Autonomous Thyroid Nodule Causing Thyrotoxicosis......Page 38
Management of Multinodular Goiter......Page 39
References......Page 41
Fine Needle Aspiration......Page 44
Benign Thyroid Tumors and Tumor-Like Nodules......Page 46
Nontoxic Multinodular Goiter/Adenomatous Hyperplasia......Page 47
Follicular Adenoma......Page 48
Subacute Thyroiditis......Page 49
Chronic Lymphocytic Thyroiditis (Hashimoto\'s Thyroiditis)......Page 50
Variants of Papillary Cancer (Chapter 6)......Page 51
Differentiated Thyroid Cancer: Follicular Cancer (Chapter 5)......Page 53
Anaplastic Thyroid Cancer (Chapter 9)......Page 54
Hematolymphoid Neoplasms (Chapter 11)......Page 55
Mesenchymal Tumors of the Thyroid......Page 56
References......Page 57
Natural History of Differentiated Thyroid Cancer......Page 60
Surgery......Page 62
Diagnostic Scanning......Page 64
Recombinant Human Thyrotropin......Page 65
Low Iodine Diet......Page 66
Interpretation of the Whole-Body Scan......Page 67
False-Positive Findings......Page 70
Thyroglobulin......Page 73
Treatment with Thyroid Hormone......Page 74
Treatment with Radioiodine 131I......Page 75
Empiric Therapy for \"Ablation of Remnants\"......Page 76
Dosimetry Using Diagnostic 124I......Page 77
Treatment After Stimulation with Recombinant Human Thyrotropin......Page 78
Side Effects and Complications......Page 79
Posttherapy Scintiscan......Page 81
Follow-Up After Treatment of Cancer......Page 83
Is 131I Necessary?......Page 84
Stunning?......Page 86
Thyroglobulin-Positive, 131I-Negative Patients......Page 87
Lithium......Page 90
References......Page 91
Thyroid Cancer and End-Stage Renal Disease......Page 99
Cancer in Lingual Thyroid......Page 100
Follicular Variant of Papillary Cancer......Page 101
Solid (Trabecular) Variant of Papillary Cancer......Page 102
Variants of Follicular Cancer: Hürthle Cell Cancer......Page 103
References......Page 104
Presentation and Diagnosis......Page 107
Surgery......Page 109
Radioiodine......Page 110
Management After 131I Treatment......Page 114
False-Positive Scans......Page 115
Complications and Long-Term Problems After 131I......Page 116
Prognosis......Page 117
References......Page 118
Treatment of Thyroid Cancer Diagnosed in Pregnancy......Page 122
Effect of 131I on Fertility and Offspring......Page 125
Inadvertent Exposure of Pregnant Patient to Internal Radiation......Page 126
References......Page 127
Pathology......Page 131
Treatment......Page 132
Surgery......Page 133
Chemotherapy......Page 134
Radioiodine......Page 135
Summary and Key Points......Page 136
References......Page 137
Pathology......Page 139
Diagnosis and Genetic Testing......Page 141
Treatment......Page 143
The Role of Postoperative Radiation and Chemotherapy......Page 145
Scintigraphic Tests......Page 146
Summary......Page 147
References......Page 148
Diagnosis......Page 152
Workup of Patient......Page 153
References......Page 154
Clinical Importance of Metastases......Page 156
Diagnosis of Metastasis to the Thyroid......Page 157
Treatment of a Metastasis to the Thyroid......Page 158
Summary and Key Points......Page 159
References......Page 160
Index......Page 162
Back Page......Page 171