Thrombolytic Therapy for Stroke

Front Matter....Pages i-xiv
Front Matter....Pages 1-1
Mechanisms of Thrombolysis....Pages 3-27
Pathogenesis of Cervico-cranial Artery Occlusion....Pages 29-41
The Ischemic Penumbra and Neuronal Salvage....Pages 43-62
Front Matter....Pages 63-63
Pre-Clinical Testing of Thrombolytic Therapy for Stroke....Pages 65-74
Combination of Thrombolytic Therapy with Neuroprotectants....Pages 75-89
Early Studies of Thrombolytic Therapy for Stroke....Pages 91-127
Phase 2 Experience with Intravenous Thrombolytic Therapy for Acute Ischemic Stroke....Pages 129-139
Intravenous Thrombolytic Therapy for Acute Ischemic Stroke....Pages 141-152
Further Analysis of NINDS Study....Pages 153-174
Intra-Arterial Thrombolysis in Acute Ischemic Stroke....Pages 175-195
Combinations of Intravenous and Intra-Arterial Thrombolysis....Pages 197-208
Front Matter....Pages 209-209
The Case for Thrombolytic Therapy in Stroke Patients....Pages 211-221
The Case Against the Present Guidelines for Stroke Thrombolysis....Pages 223-235
How to Run a Code Stroke....Pages 237-253
Interpretation of CT Scans for Acute Stroke....Pages 255-282
Identifying and Overcoming Obstacles to Acute Stroke Treatment with rt-PA....Pages 283-296
The NINDS t-PA for Acute Stroke Protocol....Pages 297-308
Research Directions and the Future of Stroke Therapy....Pages 309-310
Illustrative Cases....Pages 311-398
Back Matter....Pages 399-410