The Tourniquet Manual-Principles and Practice

Front Matter....Pages i-xx
The Concept and Diagnosis of Brain Death....Pages 1-4
Medico-Legal Aspects....Pages 5-10
Donor Organ Availability and Transplant Coordination....Pages 11-17
Selection and Management of the Donor....Pages 19-34
Selection and Evaluation of the Potential Thoracic Organ Transplant Recipient - General Considerations....Pages 35-41
Pretransplant Immunological Considerations....Pages 43-55
Immunobiology of Allograft Destruction....Pages 57-67
Maintenance Immunosuppressive Drug Therapy and Potential Major Complications....Pages 69-83
Trends in Immunosuppressive Therapy With Regard to Cytolytic Induction Therapy and Corticosteroid Withdrawal....Pages 85-88
Tacrolimus (FK506) in Thoracic Organ Transplantation....Pages 89-95
Infection in Patients Undergoing Thoracic Organ Transplantation: Epidemiology, Pathogenesis, and Clinical Management....Pages 97-110
Malignant Neoplasia in the Immunocompromised Patient....Pages 111-117
Long-Term Management and Late Complications of the Thoracic Organ Transplant Recipient....Pages 119-130
Psychiatric Aspects....Pages 131-135
Medico-social Aspects....Pages 137-140
Nutrition and Diet....Pages 141-147
A Commentary on Quality of Life after Thoracic Organ Transplantation....Pages 149-152
Experimental Development and Early Clinical Experience....Pages 153-160
Selection and Management of the Potential Candidate for Cardiac Transplantation....Pages 161-176
The Problem of Pulmonary Hypertension in the Potential Cardiac Transplant Recipient....Pages 177-183
Mechanical Circulatory Support Before Heart Transplantation....Pages 185-194
Anesthetic Management, Including Cardiopulmonary Bypass....Pages 195-197
Current Techniques of Myocardial Protection for Cardiac Transplantation....Pages 199-205
Surgical Technique of Orthotopic Heart Transplantation. I: Standard Approach....Pages 207-213
Surgical Technique of Orthotopic Heart Transplantation. 2: Bicaval ‘Total’ Approach....Pages 215-220
Immediate Postoperative Care and Potential Complications....Pages 221-227
Physiology and Pharmacology of the Transplanted Heart....Pages 229-237
Pathology of Cardiac Allograft Rejection. 1: Vascular (Microvascular)....Pages 239-252
Pathology of Cardiac Allograft Rejection. 2: Acute Cellular....Pages 253-264
Clinical Diagnosis of Acute Rejection....Pages 265-274
Treatment of Cardiac Allograft Rejection....Pages 275-280
Infection in Relation to Thoracic Transplantation....Pages 281-311
Pathology of Cardiac Allograft Vasculopathy (Chronic Rejection)....Pages 313-320
Pathogenesis of Cardiac Allograft Vasculopathy (Chronic Rejection)....Pages 321-331
Diagnosis and Management of Cardiac Allograft Vasculopathy (Chronic Rejection)....Pages 333-345
Cardiac Retransplantation - Indications and Results....Pages 347-351
Heterotopic Heart Transplantation - Indications, Surgical Techniques and Special Considerations....Pages 353-365
Heart Transplantation in Infants and Children - Indications, Surgical Techniques and Special Considerations....Pages 367-377
Exercise Rehabilitation of Cardiac Transplant Recipients....Pages 379-389
Non-cardiac Surgery in Patients with Heart Transplants - Anesthetic and Operative Considerations....Pages 391-394
Recurrence of Myocardial Disease in the Transplanted Heart....Pages 395-404
Quality of Life After Heart Transplantation....Pages 405-408
Results of Cardiac Transplantation and Factors Influencing Survival based on the Registry of the International Society for Heart and Lung Transplantation and the Cardiac Transplant Research Database....Pages 409-416
Results of Cardiac Transplantation and Factors Influencing Survival based on the Collaborative Heart Transplant Study....Pages 417-427
Lung Transplantation - Experimental Background and Early Clinical Experience....Pages 429-432
Indications, Selection and Pretransplant Management of the Potential Recipient....Pages 433-441
A Comment on Pretransplant Management of the Potential Lung Recipient....Pages 443-444
Excision and Storage of the Donor Lungs....Pages 445-449
Anesthesia for Lung Transplantation....Pages 451-456
Surgical Techniques of Single and Bilateral Lung Transplantation....Pages 457-463
Lung Size and Impact on Transplantation....Pages 465-469
The Split-Lung Technique for Lobar Transplantation....Pages 471-477
Postoperative Management of the Single Lung Transplant Patient....Pages 479-487
Physiology and Pharmacology of the Transplanted Lung....Pages 489-504
Histopathology of Lung Transplantation....Pages 505-515
Diagnosis and Management of Acute Rejection....Pages 517-526
Infection After Lung Transplantation....Pages 527-542
Management of Complications of the Airway....Pages 543-546
Diagnosis and Management of Bronchiolitis Obliterans....Pages 547-555
Pulmonary Retransplantation for Obliterative Bronchiolitis....Pages 557-564
Lung Transplantation for Cystic Fibrosis....Pages 565-571
Lung Transplantation in Infants and Children - Indications, Surgical Techniques, and Special Considerations....Pages 573-580
Airway Complications in Children Following Lung Transplantation....Pages 581-588
Living Donor Lobar Lung Transplantation....Pages 589-593
Results of Lung Transplantation and Factors influencing Survival Based on the St Louis Lung Transplant Registry....Pages 595-598
Transplantation of the Heart and Both Lungs- Experimental Background and Early Clinical Experience....Pages 599-604
Transplantation of the Heart and Both Lungs - Indications, Selection, and Evaluation....Pages 605-608
Transplantation of the Heart and Both Lungs - Organ Procurement and Recipient Surgical Techniques....Pages 609-619
Lung and Heart-Lung Transplantation: A Review of Progress and Current Status based on the Registry of the International Society for Heart and Lung Transplantation....Pages 621-634
New Pharmacologic Immunosuppressive Agents....Pages 635-660
New Monoclonal Antibodies....Pages 661-663
Immunomodulation with Photopheresis....Pages 665-667
Gene Transfer....Pages 669-673
Advances in Heart Storage....Pages 675-687
Advances in Lung Storage....Pages 689-692
Permanent Cardiac Replacement by A Total Artificial Heart: Experimental Background and Current Problems....Pages 693-702
Early Clinical Experience with Permanent Cardiac Replacement by a Mechanical Device....Pages 703-707
Long-term Cardiac Support with the HeartMate® Vented Electric Left Ventricular Assist System....Pages 709-716
Temporary Support of the Lungs - the Artificial Lung....Pages 717-728
Xenotransplantation of the Heart....Pages 729-735
Pathology of Cardiac Xenograft Rejection....Pages 737-742
Clinical Experience with Cardiac Xenotransplantation....Pages 743-747
Xenotransplantation of the Lung....Pages 749-751
Cardiomyoplasty - Skeletal Muscle Assist....Pages 753-757
Blood Pumps Constructed from Skeletal Muscle....Pages 759-765
Dynamic Cardiomyoplasty: Multicenter Clinical Trials....Pages 767-773
Cultured Cardiomyocytes....Pages 775-784
Myocardial Regeneration with Skeletal Muscle Satellite Cells....Pages 785-787
Lung Volume Reduction Surgery in Patients with Emphysema....Pages 789-795
Pulmonary Endarterectomy - Treatment of Choice for Patients with Pulmonary Hypertension due to Emboli....Pages 797-805
Back Matter....Pages 807-824