The Structure and Metabolism of the Pancreatic Islets. A Centennial of Paul Langerhans' Discovery

Content: 
Inside Front Cover, Page ifc1
Front Matter, Pages ii-iii
Copyright, Page iv
PREFACE, Page ix, S. FALKMER, B. HELLMAN, I-B. TäLJEDAL
LIST OF PARTICIPANTS, Pages xi-xii
OPENING ADDRESS, Page 1, S. FALKMER, B. HELLMAN, I.-B. TäLJEDAL
PAUL LANGERHANS A MEMORIAL LECTURE, Pages 3-11, A. LOUBATIèRES
ISLET CELL PROLIFERATION IN EXPERIMENTAL AND GENETIC DIABETES, Pages 15-23, J. LOGOTHETOPOULOS, G. BROSKY, H.F. KERN
THE SIGNIFICANCE OF AGRANULAR AND CILIATED ISLET CELLS, Pages 25-35, L. BOQUIST, S. FALKMER
PRESENT STATE OF THE EVIDENCE FOR MIXED ENDOCRINE AND EXOCRINE PANCREATIC CELLS IN SPINY MICE, Pages 37-52, L. ORCI, C. RUFENER, R. PICTET, A.E. RENOLD, CH. ROUILLER
OBSERVATIONS ON THE TYPE AND ORIGIN OF THE HORMONE–PRODUCING CELLS IN THE ZOLLINGER–ELLISON AND VERNER-MORRISON SYNDROME, Pages 53-63, W. CREUTZFELDT, E. PERINGS, C. CREUTZFELDT, M. CLASSEN
CATECHOLAMINES IN A TRANSPLANTABLE ISLET-CELL TUMOR OF THE GOLDEN HAMSTER, Pages 65-68, A.M. CESSION-FOSSION, P.J. LEFEBVRE
COMPARISON OF CULTURED AND TRANSPLANTED ISLETS OF THE GUINEA-PIG, Pages 69-72, S. MOSKALEWSKI
MONOLAYER CULTURE OF PANCREATIC ISLET CELLS, Pages 73-80, A. ANDERSSON
CONTROL OF ENDOCRINE FUNCTION IN ORGAN CULTURES OF FETAL RAT PANCREAS, Pages 81-95, A.E. LAMBERT, L. ORCI, Y. KANAZAWA, A.E. RENOLD, CH. ROUILLER
THE FINE STRUCTURE OF PANCREATIC α-CELLS UNDER NORMAL AND EXPERIMENTAL CONDITIONS, Pages 99-107, H.F. KERN
INTRACELLULAR “α-GRANULOLYSIS” IN α-CELLS OF DIABETIC ANIMALS, Pages 109-114, L. ORCI, A.E. RENOLD, CH. ROUILLER
THE CELLULAR ORIGIN OF PANCREATIC GLUCAGON, Pages 115-121, G. LUNDQUIST, S.E. BROLIN, R.H. UNGER, A.M. EISENTRAUT
ISOLATION AND HISTOCHEMICAL CHARACTERIZATION OF ISLET α-CELLS, Pages 123-129, B. PETERSSON
MONOAMINERGIC MECHANISMS IN THE PANCREATIC α-CELLS, Pages 131-140, L. CEGRELL
REGULATION OF GLUCAGON RELEASE IN VIVO, Pages 141-148, R.H. UNGER, A.M. EISENTRAUT
GLUCAGON SECRETION IN NORMAL RATS AND HAMSTERS AND IN HAMSTERS WITH A TRANSPLANTABLE ISLET CELL TUMOR, Pages 149-155, K. NONAKA, T.A.I. GRILLO, P.P. FOà
ULTRASTRUCTURAL ASPECTS OF THE FUNCTION OF RABBIT β-CELLS, Pages 159-170, S.S. LAZARUS, B.W. VOLK
THE MECHANISM OF EMIOCYTIC INSULIN RELEASE, Pages 171-180, P.E. LACY, S.L. HOWELL
EVIDENCE FOR DIFFERENT MODES OF INSULIN SECRETION, Pages 181-198, W. CREUTZFELDT, C. CREUTZFELDT, H. FRERICHS
HISTOCHEMICAL EVIDENCE FOR A SULFONYLUREA EFFECT ON THE ZINC CONTENT OF THE PANCREATIC ISLETS, Pages 199-202, A. BòNDER, G. SCHESMER
ROLE OF SULFHYDRYL COMPOUNDS AND HEAVY METALS IN THE SYNTHESIS AND STORAGE OF INSULIN, Pages 203-212, S. FALKMER, N. HAVU, L. BOQUIST
COMPARATIVE HISTOCHEMICAL STUDIES OF MAMMALIAN PANCREATIC ISLETS, Pages 213-222, P.E. PETKOV
GLUCOSE PHOSPHORYLATION AND GLUCOSE OXIDATION IN MOUSE PANCREATIC ISLETS AND THE RELEASE OF INSULIN, Pages 225-232, S.J.H. ASHCROFT, P.J. RANDLE
GLUCOSE-6-PHOSPHATASE IN PANCREATIC β-CELL METABOLISM, Pages 233-244, I.-B. TäLJEDAL
THE ACTIVITY PATTERN OF ENZYMES ASSOCIATED WITH GLYCOGEN METABOLISM IN THE ISLETS OF LANGERHANS, Pages 245-252, S.E. BROLIN, C. BERNE
ON THE FUNCTIONAL SIGNIFICANCE OF THE PANCREATIC β-CELL GLYCOGEN, Pages 253-262, B. HELLMAN, L.å. IDAHL
THE ROLE OF THE PENTOSE PHOSPHATE PATHWAY IN INSULIN SECRETION, Pages 263-273, W. MONTAGUE, K.W. TAYLOR
PHOTOKINETIC MEASUREMENTS OF THE ATP AND ADP LEVELS IN ISOLATED ISLETS OF LANGERHANS, Pages 275-282, G. WETTERMARK, L. TEGNéR, S.E. BROLIN, E. BORGLUND
QUANTITATIVE ENZYME PATTERN AND INSULIN CONTENT OF HUMAN ISLETS OF LANGERHANS, Pages 283-290,290a,291-303, W. GEPTS, F. GREGOIRE, A. VAN ASSCHE, M. DE GASPARO
ELECTRICAL ACTIVITY IN ISLET CELLS, Pages 305-313, E.K. MATTHEWS, P.M. DEAN
OXYGEN CONSUMPTION OF THE β-CELLS IN RELATION TO INSULIN RELEASE, Pages 315-329, C. HELLERSTRöM, S. WESTMAN, N. MARSDEN, D. TURNER
RESPIRATION OF THE β-CELLS IN THE PRESENCE OF SULFONYLUREAS, Pages 331-336, H. STORK, F.H. SCHMIDT, C. HELLERSTRöM, S. WESTMAN
PROINSULIN AND INSULIN BIOSYNTHESIS, Pages 339-348, J.L. CLARK, A.H. RUBENSTEIN, P.E. OYER, J.J. MACKENZIE, S. CHO, D.F. STEINER
DISTRIBUTION AND RADIOACTIVITY OF ACID-ETHANOL SOLUBLE PROTEIN, PROINSULIN, AND INSULIN IN SUBCELLULAR FRACTIONS FROM ISLET TISSUE OF THE COD (GADUS CALLARIAS), Pages 349-361, P.T. GRANT, K.B.M. REID, T.L. COOMBS, A. YOUNGSON, N.W. THOMAS
RIBONUCLEIC ACID AND PROTEIN SYNTHESIS IN ISOLATED COD-FISH ISLETS, Pages 363-370, R.J. JARRETT, H. KEEN, N.S. TRACK, K.B.M. REID
RIBONUCLEIC ACID METABOLISM AND INSULIN SYNTHESIS, Pages 371-379, R.J. JARRETT, N.S. TRACK, H. KEEN
DEMONSTRATION OF PROINSULIN IN THE β-CELLS OF BOVINE ISLETS BY A SPECIFIC FLUORESCENT ANTIBODY, Pages 381-384, J. LOGOTHETOPOULOS, C.C. YIP, M.E. COBURN
PREPARATION AND PROPERTIES OF ISOLATED MAMMALIAN INSULIN STORAGE GRANULES, Pages 385-395, H.G. COORE, B. HELLMAN, I.-B. TäLJEDAL
PROPERTIES OF ISOLATED β-GRANULES IN SUSPENSION, Pages 397-405, A.E. LAMBERT, Y. KANAZAWA, L. ORCI, G.M. GRODSKY
IN VITRO STUDIES SUGGESTING A TWO-COMPARTMENTAL MODEL FOR INSULIN SECRETION, Pages 409-421, G. GRODSKY, H. LANDAHL, D. CURRY, L. BENNETT
DYNAMICS OF INSULIN SECRETION: COMPARISON OF VARIOUS IN VITRO PREPARATIONS, Pages 423-434, E.F. PFEIFFER, R. FUSSGäNGER, M. HINZ, S. RAPTIS
BIOCHEMICAL, PHARMACOLOGICAL, AND PHYSIOLOGICAL ASPECTS OF THE ADENYLCYCLASE–PHOSPHODIESTERASE SYSTEM IN THE PANCREATIC β-CELLS, Pages 435-444, W. MALAISSE, F. MALAISSE-LAGAE
FEEDBACK REGULATION OF INSULIN SECRETION BY INSULIN: ROLE OF 3\',5\'-CYCLIC AMP, Pages 445-451, J.-C. SODOYEZ, F. SODOYEZ-GOFFAUX, P.P. FOà
A POSSIBLE ROLE OF THE PANCREATIC α1- AND α2-CELLS AS LOCAL REGULATORS OF INSULIN SECRETION, Pages 453-462, B. HELLMAN, å. LERNMARK
INTESTINAL HORMONES AND INSULIN RELEASE AND BIOSYNTHESIS, Pages 463-468, D.S. TURNER, R.J. JARRETT
THE INSULIN-RELEASING ACTIVITY OF EXTRACTS OF THE PORCINE INTESTINAL TRACT, Pages 469-476, A.J. MOODY, J. MARKUSSEN, F. SUNDBY, C. STEENSTRUP, A. SCHAICH FRIES
THE EFFECT OF GLUCOSE ON THE INSULIN SECRETION IN FOETAL AND NEWBORN RATS, Pages 477-484, K. ASPLUND
EFFECTS OF DIFFERENT METABOLITES ON THE STORAGE AND RELEASE OF INSULINBY DUCK PANCREAS IN VITRO, Pages 485-488, J.L. R-CANDELA, M. SALINAS
IONIC MECHANISMS IN THE REGULATION OF INSULIN SECRETION, Pages 489-494, R.D.G. MILNER, C.N. HALES
REMARKS ON PANCREATIC β-CELLS IN SPONTANEOUS AND EXPERIMENTAL DIABETES IN SMALL LABORATORY RODENTS, Pages 497-513, A.E. RENOLD, L. ORCI, W. STAUFFACHER, A. JUNOD, CH. ROUILLE
INSULIN SYNTHESIS AND SECRETION BY ISOLATED ISLETS OF SPONTANEOUSLY DIABETIC CHINESE HAMSTERS, Pages 515-526, A.Y. CHANG
PANCREATIC GLUCAGON SECRETION, Pages 527-531, R.H. UNGER, E. AGUILAR-PARADA, A. EISENTRAUT
THE PANCREATIC β-CELLS IN THE PATHOGENESIS OF HUMAN DIABETES MELLITUS, Pages 533-543, E. CERASI, R. LUFT
SUMMING UP OF THE CONFERENCE, Pages 547-548, B.A. HOUSSAY
INDEX OF AUTHORS AND PARTICIPANTS IN THE DISCUSSIONS, Pages 549-550
SUBJECT INDEX, Pages 551-568