The Second Messenger Cyclic Di-GMP

Content: Table of Contents      I. Second Messengers: an Overview    1. Introduction to Second Messengers: Lessons from Cyclic AMP       Alan J. Wolfe        II. General Principles: the Core    2. Moshe Benziman and the Discovery of Cyclic Di-GMP       Dorit Amikam, Haim Weinhouse, and Michael Y. Galperin    3. Ubiquity of Cyclic Di-GMP Pathways: a Bioinformatic Analysis       Michael Y. Galperin    4. The Core Pathway: Diguanylate Cyclases, Cyclic Di-GMP-Specific Phosphodiesterases, and Cyclic Di-GMP-Binding Proteins       Mark Gomelsky    5. The HD-GYP Domain and Cyclic Di-GMP Signaling       Robert P. Ryan, Yvonne McCarthy, and J. Maxwell Dow    6. Methods for Cyclic Di-GMP Detection       Christopher M. Waters    7. Making, Breaking, and Sensing of Cyclic Di-GMP: Structural, Thermodynamic, and Evolutionary Principles       Dorothy Kim, John F. Hunt, and Tilman Schirmer        III. Cyclic Di-GMP and Lifestyle Choices    8. Choosing the Right Lifestyle: Regulation of Developmental Pathways by Cyclic Di-GMP       Matthew Parsek and Phillip Aldridge    9. Role of Cyclic Di-GMP in Caulobacter crescentus Development and Cell Cycle Control       Soren Abel and Urs Jenal    10. Hierarchical Control of rdar Morphotype Development of Salmonella enterica by Cyclic Di-GMP       Ute Romling, Kristina Jonas, Ojar Melefors, Nina Grantcharova, and Agaristi Lamprokostopoulou    11. Role of Cyclic Di-GMP in Pseudomonas aeruginosa Biofilm Development       Caroline S. Harwood    12. The Scr Circuit in Vibrio parahaemolyticus Modulates Swarming and Sticking       Linda L. McCarter    13. Roles of Diguanylate Cyclases and Phosphodiesterases in Motility and Biofilm Formation in Vibrio fischeri       Alan J. Wolfe and Karen L. Visick    14. Csr (Rsm) System and Its Overlap and Interplay with Cyclic Di-GMP Regulatory Systems       Tony Romeo and Paul Babitzke    15.  Riboswitches That Sense Cyclic Di-GMP       Elaine R. Lee, Narasimhan Sudarsan, and Ronald R. Breaker    16. Role of Cyclic Di-GMP in the Regulatory Networks of Escherichia coli       Regine Hengge    17. Cyclic Di-GMP Signaling in Vibrio cholerae       Sinem Beyhan and Fitnat H. Yildiz    18. Role of Cyclic Di-GMP in Biofilm Development and Signaling in Yersinia pestis       Robert D. Perry and Alexander G. Bobrov    19. Environmental Control of Cyclic Di-GMP Signaling in Pseudomonas fluoresens: from Signal to Output       Peter D. Newell and George A. O\'Toole        IV. Cyclic Di-GMP, Pathogenesis, and Host Immunity    20. Role of Cyclic Di-GMP in Vibrio cholerae Virulence       Jason T. Pratt, Rita Tamayo, and Andrew Camilli    21. Cyclic Di-GMP Signaling and Host Immunity       David K. R. Karaolis and Theodore J. Standiford    22. Bis-(3\',5\')-Cyclic Di-GMP: Promising Adjuvant for Vaccine Design       Thomas Ebensen, Rimma Libanova, and Carlos A. Guzman        V. Conclusions    23. Cyclic Di-GMP: Using the Past To Peer into the Future       Karen L. Visick and Alan J. Wolfe