The SAGE Handbook of Drug & Alcohol Studies Biological Approaches

Cover
......Page 1
Contents......Page 6
List of Figures......Page 9
List of Tables......Page 11
Notes on the Editors and Contributors......Page 13
Introduction......Page 26
Part
I - Determination of  Substance Misuse......Page 30
Chapter
1 - Genetics and Genomics in Addiction Research......Page 32
Chapter
2 - Basic Pharmacokinetics of Substance Misuse......Page 66
Chapter
3 - Future Directions: The Role of Pharmacogenomics......Page 86
Part
II - PK and PD in Relation to Patterns of Use......Page 90
Chapter
4 - Alcohol: Pharmacokinetics and Pharmacodynamics......Page 92
Chapter
5 - Nicotine: The Pharma cokinetics  of Nicotine and Cotinine......Page 107
Chapter
6 - Opioids: A Discussion of Pharmacokinetics and Pharmacodynamics in Those  Who Misuse Drugs......Page 133
Chapter
7 - Cocaine: Pharmacokinetics, Pharmacodynamics and  Addictive Potential......Page 152
Chapter
8 - Amphetamine & Methamphetamine: Pharmacokinetics and Pharmacodynamics......Page 160
Chapter
9 - MDMA: Pharmacokinetics......Page 181
Chapter
10 - Benzodiazepines: A Discussion of  Pharmacokinetic and Pharmacodyna mic Effects......Page 191
Chapter
11 - Ketamine: The Pharmacokinetics and Pharmacodynamics in Misusing Populations......Page 206
Chapter 
12 - Cannabis: The Pharmacokinetics and Pharmacodynamics of Recreational and Medicinal Cannabis......Page 223
Chapter 13 - Synthetic Cannabinoids: The Pharmacokinetics and Pharmacodynamics of Spice and Other Synthetic Cannabinoids
......Page 242
Chapter 14 - Khat, Mephedrone and 
MDPV: Pharmacokinetic and Pharmacodynamic Parameters
......Page 278
Chapter 15 - Gamma-hydroxybutyric Acid and its Analogues: Pharmocokinetics and Pharmacodynamics
......Page 300
Chapter 16 - Polysubstance Use
......Page 312
PART III - Detection and Treatment of 
Drug and Alcohol Use
......Page 336
Chapter
17 - A Brief Overview of the Detection of Drug and Alcohol Use:  The Matching of Purposes  and Procedures......Page 338
Chapter
18 - Biomarkers of Alcohol Misuse......Page 357
Chapter
19 - Treatment of Opioid Dependence......Page 374
Chapter 20 - Wastewater Analysis for the Measurement of Population Level Drug Use: Sewage-Based Epidemiology
......Page 385
Part IV
 - Special Settings......Page 398
Chapter
21 - Forensic Toxicology and  Death Investigation......Page 400
Chapter
22 - Alcohol-related Offences,  Alcohol Use Disorders  and the Workplace......Page 406
Chapter
23 - Future Directions: What is the Way Forward for Toxicology and Forensic Research?......Page 425
PART V 
- Controversies and 
New Approaches......Page 428
Chapter
24 - Intravenous Abuse of Methylphenidate......Page 430
Chapter 25 - Non-addictive Drug Use:  The Way Forward
......Page 440
Chapter 26 - Different Approaches to 
Setting Limits for Drugs and Alcohol Use When Driving
......Page 464
Chapter 
27 - Where do Gambling and 
Internet ‘Addictions’ Belong? 
The Status of ‘Other’ Addictions......Page 475
Chapter 28 - Emerging Tobacco Trends from the Arabian Cultures (Waterpipe and Dokha): Global Prevalence, Health Risks and Propensity for Abuse
......Page 500
Chapter 29 - Treating Benzodiazepine Dependence – Abstinence or Maintenance?
......Page 514
Chapter 30 - 
ADHD: Pathways into Addiction, Diagnosis and Pharmacotherapy......Page 520
Chapter 
31 - Exploratory Models to Explain Attention Deficit Hyperactivity Disorder and its Association 
with Substance Use......Page 547