The Regeneration Promise: The Facts behind Stem Cell Therapies

Cover
Title
Copyright
End User License Agreement
Contents
Preface
	CONSENT FOR PUBLICATION
	CONFLICT OF INTEREST
	ACKNOWLEDGEMENTS
Dedication
A Bit of History
	Peter Hollands
	INTERESTING TIMES
	STEM CELLS ARE EVERYWHERE!
		Bone Marrow Stem Cells
		Back Again to 1956
		Tissue Typing or ‘Tissue Matching’
		From Embryos to Stem Cells
		From Mouse to Man?
		More Mouse Embryos!
		Stem Cells in The Blood
		Cord Blood Stem Cells
		Cord Blood Transfusion
		Human Embryonic Stem Cells
		Adult or Fetal Stem Cells?
		Umbilical Cord Tissue and Placental Tissue Stem Cells
		Fat Stem Cells!
		The Tooth Fairy and Stem Cells
		‘Man Made’ Stem Cells
	INITIAL CONCLUSIONS
	KEY POINTS OF CHAPTER 1
Blood and Toil
	Peter Hollands
	‘BLOOD FORMING’ STEM CELLS
		Bone Marrow Transplantation
		Haploidentical Transplantation
		Find the Match
		Bone Marrow Stem Cell Banks
		Preparation for Transplant
		Transplant Time
		Recovery
		It’s Not Easy!
	‘TISSUE FORMING’ STEM CELLS IN BONE MARROW
		Clinical Trials
			Four Phases
	BONE MARROW STEM CELLS AND HEART ATTACK
	BONE MARROW STEM CELLS AND AUTOIMMUNE DISEASE
	THE RIGHT STEM CELL AND A HOLISTIC APPROACH
	BONE MARROW STEM CELLS AND OSTEOARTHRITIS
		Clinical Trials
	BONE MARROW AND OTHER DISEASES
	KEY POINTS OF CHAPTER 2
A Bouncing Baby!
	Peter Hollands
	CORD BLOOD STEM CELLS
		Cord Blood Stem Cell Collection Process
		Cord Blood Stem Cell Storage Options
		Cord Blood Laboratory Processing
		Cord Blood Stem Cells Pros and Cons
		Cord Blood Stem Cell Double Transplants and Expansion
		Quality not Quantity
		Cord Blood Stem Cell Clinical Trial for Cerebral Palsy
		Cord Blood Stem Cell Clinical Trial for Autism
	KEY POINTS OF CHAPTER 3
Baby Blues
	Peter Hollands
	CHOICES
		Public and Private Cord Blood Banks
		The Development of Private Cord Blood Banking
		The Development of Public Cord Blood Banking
		Public or Private Cord Blood Storage?
		Cord Blood Guidance
		Whole or Processed?
		More Questions
		To Clamp or Not to Clamp? That is the Question…
		The UK Royal Colleges
		Umbilical Cord Blood Plasma
	KEY POINTS OF CHAPTER 4
That's a Nice Vein
	Peter Hollands
	PERIPHERAL BLOOD STEM CELLS
		Potential Problems
		Improved Mobilisation Technology
		Clinical Trials Using Peripheral Blood Stem Cells
	KEY POINTS OF CHAPTER 5
The Vatican and More
	Peter Hollands
	A COMPLEX DEBATE
		Human Embryonic Stem Cell Production
		The Human Embryo
		Is There an Elephant in The Room?
		Clinical Trials
	A FINAL NOTE OF OPTIMISM!
	KEY POINTS OF CHAPTER 6
No One Likes the Dentist
	Peter Hollands
	OFF TO SEE THE DENTIST
		Milk and Adult Teeth
		Milk Teeth Collection
		Stem Cells from Adult Teeth
		Are There Enough Stem Cells?
		Tooth Implants
		Clinical Trial
	KEY POINTS OF CHAPTER 7
Who Are You Calling Fat?
	Peter Hollands
	FAT: GOOD OR BAD?
		Liposuction
		Processing of Fat Stem Cells Using Enzymes
		Processing of Fat Stem Cells Using A Mechanical Approach
		Caution is Needed
		Clinical Trials and ‘Freeze Young’
		Fat Stem Cells and Osteoarthritis
	KEY POINTS OF CHAPTER 8
A Human Touch
	Peter Hollands
	MAN-MADE
		Good or Bad?
		Organoids
		Clinical Trials
	KEY POINTS OF CHAPTER 9
Baby is Back!
	Peter Hollands
	STEM CELLS IN TISSUES RELATED TO PREGNANCY
		Umbilical Cord Tissue
		Clinical Trials of Cord Tissue Stem Cells
		Placenta Stem Cells
		Amniotic Membrane and Amniotic Fluid Stem Cells
		Clinical Trials of Amniotic Membrane Stem Cells
		Research and Clinical Trial of Amniotic Membrane Stem Cells
	KEY POINTS OF CHAPTER 10
Kill or Cure?
	Peter Hollands
	STEM CELL TREATMENTS (CAVEAT EMPTOR: BUYER BEWARE)
		The Regeneration Promise
		Human Use
		Using Your Own Stem Cells
		Celebrity Endorsement
		There is Hope
	KEY POINTS OF CHAPTER 11
A Final Thought
	Peter Hollands
	SOME THINGS WORK SOME THINGS DO NOT
		Cord Blood Transfusion
		Platelet Rich Plasma (PRP)
		Very Small Embryonic Like Stem Cells and Laser Technology
		Cell Reprogramming
		Exosomes
		Quantum Medicine
		Nanotechnology
		3D Printing
		Skeletal Muscle Stem Cells
		Liver Stem Cells
		Recent Progress in Stem Cell Therapy of Heart Disease
		Anti-Ageing
		A Final Thought
	KEY POINTS OF CHAPTER 12
	SUGGESTED FURTHER READING
	USEFUL LINKS
Glossary
	GLOSSARY
Subject Index
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