The Proteasomal System in Aging and Disease

Content: 
Copyright
Page iv

Contributors
Pages ix-x

Preface
Pages xi-xiii
Tilman Grune

Chapter 1 - Structure of the Proteasome
Pages 1-39
Tobias Jung, Tilman Grune

Chapter 2 - Structure and Function of the Ubiquitin–Proteasome System: Modulation of Components
Pages 41-74
Niki Chondrogianni, Efstathios S. Gonos

Chapter 3 - Immunoproteasomes: Structure, Function, and Antigen Presentation
Pages 75-112
Deborah A. Ferrington, Dale S. Gregerson

Chapter 4 - Interactions of the Proteasomal System with Chaperones: Protein Triage and Protein Quality control
Pages 113-160
Marc Kästle, Tilman Grune

Chapter 5 - Proteasome Inhibitors
Pages 161-226
Boris Cvek

Chapter 6 - Degradation of Damaged Proteins: The Main Function of the 20S Proteasome
Pages 227-248
Andrew M. Pickering, Kelvin J.A. Davies

Chapter 7 - Changes of the Proteasomal System During the Aging Process
Pages 249-275
Martin A. Baraibar, Bertrand Friguet

Chapter 8 - Proteasome and Cancer
Pages 277-293
Betul Catalgol

Chapter 9 - The Ubiquitin–Proteasome System and Cardiovascular Disease
Pages 295-346
Saul R. Powell, Joerg Herrmann, Amir Lerman, Cam Patterson, Xuejun Wang

Chapter 10 - Role of the Ubiquitin–Proteasome in Protein Quality Control and Signaling: Implication in the Pathogenesis of Eye Diseases
Pages 347-396
Fu Shang, Allen Taylor

Chapter 11 - Proteasome and Neurodegeneratıve Diseases
Pages 397-414
Betul Catalgol, Tilman Grune

Index
Pages 415-422