The Molecular Basis of Cancer

Content: 
Front Matter, Page iii
Copyright, Page iv
Dedication, Page v
Contributors, Pages vii-xviii
Preface, Page xix
1 - Cancer: A Genetic Disorder, Pages 3-18.e1
2 - Oncogenes and Signal Transduction, Pages 19-34.e3
3 - Tumor Suppressor Genes, Pages 35-46.e1
4 - DNA Repair Pathways and Human Cancer, Pages 47-66.e2
5 - Epigenetics and Cancer, Pages 67-78.e3
6 - Infectious Agents and Cancer, Pages 79-102.e4
7 - Environmental Carcinogenesis, Pages 103-128.e2
8 - Animal Models: Flies, Fish, and Yeast, Pages 129-144.e2
9 - Genetic Mouse Models of Cancer, Pages 145-154.e2
10 - Cancer Stem Cells and the Microenvironment, Pages 157-164.e3
11 - Regulation of the Cell Cycle, Pages 165-178.e2
12 - Cell Growth, Pages 179-190.e1
13 - The Metabolism of Cell Growth and Proliferation, Pages 191-208.e2
14 - Apoptosis, Necrosis, and Autophagy, Pages 209-228.e3
15 - Cellular Senescence, Pages 229-238.e2
16 - The Role of the Microenvironment in Tumor Initiation, Progression, and Metastasis, Pages 239-256.e5
17 - Tumor Angiogenesis, Pages 257-268.e2
18 - Invasion and Metastasis, Pages 269-284.e2
19 - Inflammation and Cancer, Pages 285-296.e3
20 - Cancer Systems Biology: The Future, Pages 297-314.e3
21 - Biomarkers for Assessing Risk of Cancer, Pages 317-330.e3
22 - Protein Biomarkers for Detecting Cancer: Molecular Screening, Pages 331-346.e5
23 - The Technology of Analyzing Nucleic Acids in Cancer, Pages 347-356.e1
24 - Understanding and Using Information about Cancer Genomes, Pages 357-368.e3
25 - High-Content Analysis with Cellular and Tissue Systems Biology: A Bridge between Cancer Cell Biology and Tissue-Based Diagnostics, Pages 369-392.e7
26 - Molecular Genetics of Acute Lymphoblastic Leukemia, Pages 395-406.e1
27 - Molecular Biology of Childhood Neoplasms, Pages 407-420.e2
28 - Biology of Adult Myelocytic Leukemia and Myelodysplasia, Pages 421-432
29 - Lymphoma, Pages 433-454.e3
30 - Multiple Myeloma, Pages 455-466.e4
31 - Molecular Mechanisms of Esophageal Cancer, Pages 467-474.e2
32 - Molecular Basis of Lung Cancer, Pages 475-490.e1
33 - The Molecular Pathogenesis of Head and Neck Cancer, Pages 491-498.e2
34 - Colon and Rectal Cancer, Pages 499-514.e2
35 - Molecular Pathogenesis of Pancreatic Adenocarcinoma, Pages 515-522.e2
36 - The Molecular Biology of Breast Cancer, Pages 523-530.e3
37 - Molecular Pathogenesis of Ovarian Cancer, Pages 531-548.e2
38 - Molecular Basis of Prostate Cancer, Pages 549-560.e1
39 - Molecular Abnormalities in Kidney Cancer, Pages 561-572.e1
40 - The Biology of Primary Brain Tumors, Pages 573-580.e1
41 - Epithelial Skin Cancer, Pages 581-590.e1
42 - Molecular Basis for Treating Cutaneous Molecular, Pages 591-600.e3
43 - Thyroid Cancer, Pages 601-608.e2
44 - Soft Tissue Sarcomas, Pages 609-618.e2
45 - From Bench to Bedside with Targeted Therapies, Pages 621-634.e2
46 - Cancer Therapeutics, Pages 635-650.e1
47 - Natural and Acquired Resistance to Cancer Therapies, Pages 651-660.e4
48 - Phase I Trials Today, Pages 661-676.e2
49 - Pharmacogenomics, Pages 677-682.e1
50 - Monoclonal Antibodies for the Treatment of Cancer, Pages 683-694.e3
51 - Cancer and the Cellular Immune Response, Pages 695-708.e2
52 - Cancer Immunotherapy with Vaccines and Checkpoint Blockade, Pages 709-738.e8
53 - Interferons, Pages 739-752.e7
54 - Gene Therapy and Oncolytic Viruses, Pages 753-768.e3
55 - RNA as a Therapeutic Molecule, Pages 769-778.e2
56 - Heat Shock Protein 90 and the Proteasome: Housekeeping Proteins That Are Also Molecular Targets for Cancer Therapy, Pages 779-788.e3
57 - Hematopoietic Growth Factors and Cytokines, Pages 789-808.e4
58 - Cancer Chemoprevention, Pages 809-824.e4
59 - Molecular Pathology, Pages 825-834.e1
Index, Pages 835-863