The Merkel Cell: Structure-Development-Function-Cancerogenesis

Front Matter....Pages I-XIV
Front Matter....Pages 1-1
Merkel Nerve Endings Functioning as Mechanoreceptors in Vertebrates....Pages 3-6
The Three-Dimensional Microanatomy of Merkel Cells....Pages 7-12
Staining of Living Merkel Cells with FM Dyes....Pages 13-18
Distribution of Merkel Cells in Normal Skin and Mucosae in Dogs....Pages 19-24
Merkel Cells in Human Transplanted Flaps....Pages 25-28
Merkel Cells in Malassez Epithelium....Pages 29-32
Morphological Changes in Merkel Cells of Mucosa Underlying Dentures....Pages 33-36
A Study on the Sensory System of Peri-Implant Tissue — Behavior of Merkel Cells and Nerve Fibers....Pages 37-40
Merkel Nerve Endings in Sinus Hairs of Young and Aged Rats....Pages 41-48
Immunohistochemical Characterization of Normal Canine Merkel cells....Pages 49-55
Merkel Cells in the Human Fetal and Adult Esophagus....Pages 57-64
Cellular Localization of Prepro-Orexin and Orexin Receptors (Ox1R and Ox2R) in Merkel Cells....Pages 65-70
Possible Functional Significance of Spatial Relationship Between Merkel Cells and Langerhans Cells in Human Hair Follicles....Pages 71-77
Neurobiology of the Murine Pelage Hair Follicle....Pages 79-86
Front Matter....Pages 87-87
Mammalian Merkel Cells Are Neural Crest Derivatives....Pages 89-96
Merkel Cells Are Postmitotic Cells of Neural Crest Origin....Pages 97-104
Dissociation, Quantification and Culture of Normal Human Merkel Cells Among Epidermal Cell Populations Derived from Glabrous and Hairy Skin Sites....Pages 105-112
Growth of Nerve Fibers to Merkel Cells Observed in Co-Culture of Sensory Ganglia and Sinus Hair Follicles....Pages 113-120
Merkel Cell Development is Independent of L1 Adhesion Molecule....Pages 121-123
Front Matter....Pages 125-125
The Functional Significance of the Vibrissal System of Marine Mammals....Pages 127-135
Front Matter....Pages 125-125
Confocal Microscopic Analysis of Merkel Innervation in the Cat Mystacial Vibrissa Follicles....Pages 137-141
Voltage-Dependent Calcium Channels in Merkel Cells of Hamster Oral Mucosa....Pages 143-146
Localization of Signal Transduction Proteins in the Merkel Cell Axon Complex....Pages 147-154
Are Glutamate Receptors Involved in Transmission at the Junction Between Merkel Cell and Nerve Terminal?....Pages 155-162
Glutamate Receptor-Like Immunoreactivity in Rat Vibrissal Merkel Cells....Pages 163-168
Transduction in Merkel Cell Mechanoreceptors — What Is the Job of the Merkel Cell?....Pages 169-176
Front Matter....Pages 177-177
Merkel Cell Carcinoma — A Short Review....Pages 179-185
Histochemistry of Glycoconjugates in Merkel Cell Carcinomas....Pages 187-194
Gene Expression Profiling Reveals Two Distinct Subtypes of Merkel Cell Carcinoma....Pages 195-202
Expression of Developmentally Regulated Transcription Factors in Merkel Cell Carcinoma....Pages 203-218
Expression Patterns of Connexins in Merkel Cell Carcinoma and Adjacent Epidermis....Pages 219-222
Expression Patterns of Tight Junction Proteins in Merkel Cell Carcinoma....Pages 223-226
Ganglioside Profiles of Merkel Cell Carcinoma....Pages 227-230
MOC-31, Cytokeratin 7 and S-100 Protein Immunoreactivity in Merkel Cell and Merkel Cell Carcinoma....Pages 231-236
Merkel Cell Carcinomas Possess Telomerase Activity....Pages 237-240
Chemotherapy in Merkel Cell Carcinoma with Distant Metastasis — Proposal of a Pan-European Clinical Trial....Pages 241-243
Back Matter....Pages 245-248