The Living Brain and Alzheimer’s Disease

Front Matter....Pages I-XV
Neuropathology of Alzheimer’s Disease, as Seen in Fixed Tissues....Pages 1-15
Cerebrospinal Fluid Biomarkers for the Diagnosis of Alzheimer’s Disease....Pages 17-24
The Living Brain and Alzheimer’s Disease....Pages 25-31
In Vivo Imaging of Alzheimer Pathology in Transgenic Mice using Multiphoton Microscopy....Pages 33-45
In Vivo Magnetic Resonance of Amyloid Plaques in Alzheimer’s Disease Model Mice....Pages 47-59
Measuring Progression in Alzheimer’s Disease using Serial MRI: 4D MRI....Pages 61-74
Validating MRI Measures of Disease Stage and Progression in Alzheimer’s Disease....Pages 75-86
Dynamic Mapping of Alzheimer’s Disease....Pages 87-112
Development of Benzothiazole Amyloid-Imaging Agents....Pages 113-122
First PET Study with a Benzothiazol Amyloidimaging Agent (PIB) in Alzheimer’s Disease Patients and Healthy Volunteers....Pages 123-137
Mild Cognitive Impairment (MCI): Predicting Conversion to Clinically Probable Alzheimer’s Disease with Fluoro-Deoxy-Glucose PET....Pages 139-150
Positron Emission Tomography and Magnetic Resonance Imaging in the Study of Cognitively Normal Persons at Differential Genetic Risk for Alzheimer’s Dementia....Pages 151-177
Back Matter....Pages 179-180