The Future of the Brain Sciences: Proceedings of a Conference held at the New York Academy of Medicine, May 2–4, 1968

Front Matter....Pages i-xxxix
On the Basis of Behavior in Single Cells....Pages 1-16
Front Matter....Pages 17-17
What is Memory that it May Have Hindsight and Foresight as Well?....Pages 19-64
The Physiology of Remembering....Pages 65-87
Idea, Image and Memory....Pages 89-89
Developmental and Chemical Specificity and the Cognitive Tile....Pages 90-90
Spatial and Temporal Relationships and the Cognitive Tile....Pages 91-93
Feedback Loops and the Tesselation Model....Pages 93-94
Some Functional Specifications which Must be Met by the Biochemical Mechanisms which Store Memory....Pages 94-97
On the Role of Nucleic Acids in Computer Theories....Pages 98-102
On Searching for Engrams....Pages 103-104
On Recognition Molecules in Circuitry (Pigeon Brain Mucoids in Training, Learning and Memory)....Pages 104-113
More on Recognition Molecules....Pages 114-116
The Molecular Structure of Membranes....Pages 117-157
Functional Aspects of Synaptosomes....Pages 159-178
The Amount of Acetylcholine in Synaptic Vesicles....Pages 179-179
Dynamics of Protein Metabolism in the Nervous System....Pages 181-196
Problems of Genetic Expression in the Nervous System....Pages 197-215
Odd Electron Molecular Effects in Eye, Nerve, and Brain....Pages 217-233
Free Radical Characteristics: Their Possible Relation to Transduction in the Visual System....Pages 235-236
The Effect of Environment Upon the Developing Brain....Pages 237-252
Front Matter....Pages 17-17
On Brain Free Amino Acid Pools....Pages 253-255
Developmental Approach to Psychobiology: A Research Program....Pages 257-264
Trends in Brain Research on Learning and Memory....Pages 265-279
Some Considerations of the Effects of Short Term Learning on the Incorporation of Uridine into RNA and Polysomes of Mouse Brain....Pages 281-291
Hybridization of Nucleic Acids....Pages 292-293
Effect of Age on Brain DNA and Protein....Pages 293-295
Synthesis of Macromolecules....Pages 295-296
Redundancy of DNA Nucleotide Sequences....Pages 296-296
Effects of Stress....Pages 296-296
Fate of Synthesized Protein....Pages 297-297
Specificity of Nucleic Acid Changes Observed....Pages 297-301
Perspectives of the Research on the Integrative Activity of the Brain....Pages 303-311
What is an Adequate Stimulus in a Perceptual Learning Situation?....Pages 313-316
Relations between Behavioral and Other Biological Disciplines in Investigation of Brain Processes in Learning and Memory....Pages 317-333
Memory Consolidation and the Distinction between Short-Term and Long-Term Memory....Pages 335-340
Protein Synthesis and Memory Formation....Pages 341-344
Implications of Studies with Inhibitors on Cerebral Protein Synthesis for “Molecular” and “Molar” Views of Memory....Pages 344-348
Training, Neuronal Cell Process Growth, and Protein Synthesis....Pages 349-349
Interpretation of Puromycin Inhibition Effect....Pages 349-352
On the Need to Better Understand Protein Synthesis in Brain....Pages 352-353
Front Matter....Pages 17-17
Facilitation of Memory Storage Processes....Pages 355-370
Distinction between Drug Influence on Performance and on Learning....Pages 371-371
Effect of Strychnine on Post Shock Amnesia....Pages 371-372
Number of Cells Involved in Strychnine Effect....Pages 372-373
Chemical Transfer of Learning....Pages 373-374
Terminology....Pages 375-375
Front Matter....Pages 377-377
The Role of Phenylalanine in Mental Development....Pages 379-387
Should Low Phenylalanine Diet be Given During Pregnancy? Efficacy of the Diet....Pages 389-395
Recent Studies in Two Inborn Errors of Glycolipid Metabolism....Pages 397-415
Some Biochemical Features Shared by Different Lipidosis Syndromes....Pages 417-419
Schizophrenic and Affective Psychosis: Twin and Family Studies....Pages 421-458
The Variables of Birth Order and Fetal Nutrition....Pages 459-460
Relationship between Birth Weight and Adult Protein Bound Iodine....Pages 461-462
Present Directions in the Investigation of Dimethoxyphenethylamine....Pages 463-471
Relationship between Urinary Constituents and Exacerbations of Behavior in Schizophrenic Patients....Pages 473-484
Pathogenetic Studies of Schizophrenia: Ferritin and Fluorescein Labeling of IgG....Pages 485-499
Organic Approaches to Schizophrenia....Pages 501-517
The Biochemistry of Affective Disorders....Pages 519-524
Hormone Imbalance in Depressive States....Pages 525-553
A Psychopharmacological Approach to Biochemical Research in Psychoses....Pages 555-559
Front Matter....Pages 377-377
On the Predominant Affect and the Phase of Psychotic Illness....Pages 561-562
On the Need for Specificity in the Description of Clinical Function in Somatic Studies of Psychotic Patients....Pages 562-567
Schizophrenia as a Group of Diseases....Pages 568-570
On Reproductive Functions in Schizophrenic Patients....Pages 570-570
Increasing Validity of Biochemical Studies in Mental Disorders....Pages 571-573
Manfred Sakel, Karl Dussik, Max Rinkel and the Development of Biological Psychiatry....Pages 575-581
Back Matter....Pages 583-603