The Chemokines: Biology of the Inflammatory Peptide Supergene Family II

Front Matter....Pages i-xv
Chemotactic and Inflammatory Cytokines — CXC and CC Proteins....Pages 1-11
Induction of Chemotactic Cytokines by Minimally Oxidized Ldl....Pages 13-18
The Immunopathology of Chemotactic Cytokines....Pages 19-28
Receptor/Ligand Interactions in the C-C Chemokine Family....Pages 29-37
Adhesion Molecules in Acute and Chronic Lung Inflammation....Pages 39-45
Monocyte Chemotactic Protein-1 (MCP-1): Signal Transduction and Involvement in the Regulation of Macrophage Traffic in Normal and Neoplastic Tissues....Pages 47-54
Secretion of Monocyte Chemoattractant Protein-1 (MCP-1) by Human Mononuclear Phagocytes....Pages 55-64
L-Arginine/Nitric Oxide Pathway: A Possible Signal Transduction Mechanism for the Regulation of the Chemokine IL-8 in Human Mesangial Cells....Pages 65-75
Some Aspects of NAP-1/IL-8 Pathophysiology II: Chemokine Secretion by Exocrine Glands....Pages 77-85
Molecular Mechanism of Interleukin-8 Gene Expression....Pages 87-97
Basophil Activation by Members of the Chemokine Superfamily....Pages 99-110
Monocyte Chemotactic Proteins Related to Human MCP-1....Pages 111-118
Platelets Secrete an Eosinophil-Chemotactic Cytokine which is a Member of the C-C-Chemokine Family....Pages 119-127
Neutrophil-Activating Peptide ENA-78....Pages 129-137
The Effects of Human Recombinant MIP-1α, MIP-1β, and Rantes on the Chemotaxis and Adhesion of T Cell Subsets....Pages 139-146
Promiscuity of Ligand Binding in the Human Chemokine Beta Receptor Family....Pages 147-153
Structural and Functional Characterization of the Interleukin-8 Receptors....Pages 155-169
Elucidation of Structure Function Relationships in the IL-8 Family by X-ray Crystallography....Pages 171-182
Overview of Chemokines....Pages 183-186
Regulation of Cytokine Secretion by Poxvirus Encoded Proteins....Pages 187-187
Interleukin-8 Expression in Gastric Cancer....Pages 188-188
Synergistic II-8 Synthesis by Human Peritoneal Mesothelial Cells (Hpmc) Following II-1β and Tnfα Treatment....Pages 188-189
Detection of a Potent Chemotactic Activity in Supernatants from Human Monocytes Stimulated with Endothelin-1 (ET-1)....Pages 189-189
Glioblastoma Secrete Mcp-1, A Monocyte Chemotactic Factor....Pages 190-190
Neutrophil Chemotactic Activity In The Bronchoalveolar Lavage Fluid Of Asthmatics....Pages 190-190
The Chemoattractant Properties of Interleukin-4....Pages 191-191
Il-8 Induced Chemotaxis of Peripheral Neutrophils in Children with Cystic Fibrosis (Cf)....Pages 191-192
Unusual Properties in Vitro and in Vivo of 198, an Antibody that Recognizes Rabbit Cd11b....Pages 192-192
Effect of Monocyte Chemotactic Cytokine Gene Transfer on Macrophage Infiltration, Growth and Metastatic Behaviour of a Murine Melanoma....Pages 192-193
Expression of Monocyte Chemotactic Protein-1 (Mcp-1) by Monocytes and Endothelial Cells Exposed to Thrombin....Pages 193-194
IL-8 Production During Urinary Tract Infection....Pages 194-194
Nap-1/IL-8 Receptor Expression on Human Neutrophils....Pages 194-194
Macrophage-Derived Neutrophil Chemotactic Factor (MNCF) Induces Neutrophil Migration Through Lectin-Like Activity....Pages 195-195
Interleukin 8 Release From Human Pmn Is Modified By Airborne Particulated Matter....Pages 195-196
Interleukin-8 Induces the Expression of Hla-Dr Antigen on Human Keratinocytes....Pages 196-196
Cloning, Sequencing and Expression of Ovine Neutrophilattractant Protein-1/IL-8 and Monocyte Chemoattractant Protein-1....Pages 197-197
Inhibition of Lps-Mediated Responses in Human Whole Blood by Recombinant Bactericidal/Permeability Increasing Protein....Pages 197-198
The Activity of IL-8 in Combination with Gmcsf and TNFα....Pages 198-198
Induction of IL-8 in Inflammatory Bowel Disease....Pages 198-199
Elevated Circulating and Tissue IL-8 in Alcoholic Hepatitis....Pages 199-199
Expression of Monocyte Chemoattractant Protein-1 in Basal Keratinocytes of Psoriatic Lesions....Pages 200-200
IL-8 Concentration in β-Thalassaemia and After Bone Marrow Transplantation....Pages 200-201
Cytokine Production in Felty’s Syndrome....Pages 201-201
The Lymphocyte Attractant Effects of Interleukins lα and 8 a Are Not Due to the Release of a Secondary Chemoattractant Factor....Pages 202-202
Serial Changes in Circulating Interleukin-8 and Neutrophil Elastase after Major Surgery....Pages 202-203
Role of Interleukin-8 in the Pathogenesis of Neutrophilmediated acute Lung Injury....Pages 203-203
Interleukin-8 in Acute Meningococcal Infections; Correlation with Severity of Disease....Pages 204-204
IL-6 And IL-8 Levels in Patients with Rheumatoid Arthritis....Pages 204-205
Plasma Interleukin 8 Levels in Patients with Septic Shock....Pages 205-205
Inhibitory Effect of Protease-Inhibitor for Production of Interleukin 8 (IL-8) and Polymorphonuclear Leukocyte Elastase (Pmne)....Pages 205-206
Effect of Diluents and Capture Antibodies on Detection of NAP-1 by Sandwich Elisa....Pages 206-206
Do the Two Types of IL-8 Receptors on Human Neutrophils Mediate Different Cellular Responses?....Pages 207-207
Interleukin 8 Plays a Fundamental Role in Inflammatory Processes in Vivo....Pages 207-208
Endothelial Cell Binding of NAP-1/IL-8: Role in Neutrophil Emigration....Pages 208-208
Heparin Binding of NAP-1/IL-8: The Effect of Heparin and Related Glycosaminoglycans on in Vitro Neutrophil Responses to NAP-1/IL-8....Pages 209-209
The Effect of 5-Lipoxygenase Inhibitors on the Activity of IL-8....Pages 209-210
Chemotactic Cytokine Generation by Human Lung Microvascular Endothelial Cells: Differential Regulation by Gamma Interferon....Pages 210-210
The Effect of Haemofiltration on Circulating Cytokines in Children Undergoing Cardiopulmonary Bypass: A Preliminary Study....Pages 211-211
Interleukin 8 (IL-8) is Produced by the Bronchoalveolar Lavage Cell Population from Patients with Active but not Inactive Sarcoidosis....Pages 211-212
Gastric Interleukin-8 and Interleukin-8 IgA Autoantibodies in Helicobacter Pylori Infection....Pages 212-212
Eosinophils from Allergic Individuals, but not Normal Individuals, Show Chemotactic Responsiveness to NAF/IL-8....Pages 213-213
Monocyte Chemotactic Peptide-1 (Mcp-1) and NAP-1/IL-8 Formation in Baboon Septicemia are Partially TNF Dependent....Pages 213-213
Increased Expression of Monocyte Chemoattractant Protein-1 (Mcp-1) in Glomeruli From Rats With Anti Thy 1.1 Glomerulonephritis....Pages 214-215
Role of Macrophage Inflammatory Protein (Mip)-Lα in Granulomatous Inflammation....Pages 215-215
Nap-1/Il-8 Is a Weak Inducer of T Cell Migration Into Skin....Pages 216-216
IL-8-Stimulated Lymphocyte Locomotion in Antigen- Or Mitogen-Activated Mononuclear Cell Cultures....Pages 216-216
In Vivo Studies of Rantes and the Recruitment of Lymphocytes to Inflammatory Sites....Pages 217-217
IL-1 and TNF Induced Up-Regulation of IL-8 Receptors on Human Epidermal Cells....Pages 217-218
Promiscuity Of Ligand Binding In The Chemokine Beta Receptor Family....Pages 218-218
Differentiation-Specific Expression of a Novel G Protein-Coupled Cytokine Receptor from Burkitt’s Lymphoma....Pages 218-219
Signal Transduction by Monocyte Chemotactic Protein-1 (MCP-1) and Cross-Desensitization with Other Members of the Chemokine-β Subfamily in Human Monocytes....Pages 219-219
Mechanisms of Zymosan Induced IL-8 Generation in Vivo....Pages 220-220
The Effects of Intranasal Challenge with Interleukin-8 (IL-8)....Pages 220-221
Interleukin-8 Down-Regulates the Oxidative Burst Induced by Tumor Necrosis Factor Alpha in Neutrophils Adherent to Fibronectin....Pages 221-221
Identification of a Novel Tumor-Derived Monocyte Chemotactic Factor: Relationship with Tissue Inhibitor of Metalloproteinase....Pages 222-222
α-Melanocyte Stimulating Hormone Inhibits Human Epidermal Cell and Polymorphonuclear Leukocyte Chemotaxis....Pages 222-223
Mip-1 Alpha: A Potent Stem Cell Inhibitor....Pages 223-223
Back Matter....Pages 225-227