The Cell Cycle in the Central Nervous System

Front Matter....Pages i-xvii
Front Matter....Pages 1-1
Methodological Considerations in the Evaluation of the Cell Cycle in the Central Nervous System....Pages 3-12
Neural Stem Cells....Pages 13-22
Progenitors and Precursors of Neurons and Glial Cells....Pages 23-29
Vasculogenesis and Angiogenesis....Pages 31-41
Neuronal Migration and Malformations of Cortical Development....Pages 43-55
Front Matter....Pages 57-57
Genome-Wide Expression Profiling of Neurogenesis in Relation to Cell Cycle Exit....Pages 59-70
Neurogenesis and Apoptotic Cell Death....Pages 71-79
Ion Channels and the Cell Cycle....Pages 81-94
Nonsynaptic GABAergic Communication and Postnatal Neurogenesis....Pages 95-104
Critical Roles of Ca 2+ and K + Homeostasis in Apoptosis....Pages 105-118
Mammalian Neural Stem Cell Renewal....Pages 119-139
Front Matter....Pages 141-141
Methods of Determining Apoptosis in Neuro-Oncology....Pages 143-161
Cell Cycle, Neurological Disorders, and Reactive Gliosis....Pages 163-175
Potassium Channels, Cell Cycle, and Tumorigenesis in the Central Nervous System....Pages 177-191
Front Matter....Pages 193-193
Enhanced Neurogenesis Following Neurological Disease....Pages 195-206
Endothelial Injury and Cell Cycle Re-Entry....Pages 207-219
The Contribution of Bone Marrow-Derived Cells to Cerebrovascular Formation and Integrity....Pages 221-231
Microvessel Remodeling in Cerebral Ischemia....Pages 233-244
Vascular and Neuronal Effects of VEGF in the Nervous System....Pages 245-264
Epidermal Growth Factor Receptor in the Adult Brain....Pages 265-277
Front Matter....Pages 279-279
Neurodegeneration and Loss of Cell Cycle Control in Postmitotic Neurons....Pages 281-297
Cell Cycle Activation and the Amyloid-β Protein in Alzheimer’s Disease....Pages 299-308
Neuronal Precursor Proliferation and Epileptic Malformations of Cortical Development....Pages 309-318
Vascular Differentiation and the Cell Cycle....Pages 319-329
Adult Neurogenesis and Central Nervous System Cell Cycle Analysis....Pages 331-358
Neurogenesis in Alzheimer’s Disease....Pages 359-370
Front Matter....Pages 371-371
p53 and Multidrug Resistance Transporters in the Central Nervous System....Pages 373-388
Signaling Modules in Glial Tumors and Implications for Molecular Therapy....Pages 389-417
Detection of Proliferation in Gliomas by Positron Emission Tomography Imaging....Pages 419-432
Transformation of Normal Astrocytes Into a Tumor Phenotype....Pages 433-447
Mechanisms of Gliomagenesis....Pages 449-462
Front Matter....Pages 463-463
Cell Cycle of Encapsulated Cells....Pages 465-475
Viral Vector Delivery to Dividing Cells....Pages 477-493
Electrical Stimulation and Angiogenesis....Pages 495-509
Developmental and Potential Therapeutic Aspects of Mammalian Neural Stem Cells....Pages 511-524
Mammalian Sir2 Proteins....Pages 525-540
Back Matter....Pages 541-563