The Biology of Taurine: Methods and Mechanisms

Front Matter....Pages i-xiv
Front Matter....Pages 1-1
Cardiovascular Pharmacology and Experimental Therapeutics of Taurine and Related Compounds....Pages 3-22
Front Matter....Pages 23-23
Introduction: Biochemistry, Nutrition and Development....Pages 25-28
The Stabilizing Protein, Protein-A, of Cysteine Dioxygenase....Pages 29-38
The Oxidation of Hypotaurine to Taurine: Bis -Aminoethyl-α-Disulfone, A Metabolic Intermediate in Mammalian Tissue....Pages 39-48
Renal Taurine Transport — Recent Developments....Pages 49-59
Taurine Conjugation of Bile Acids Protects Human Cells in Culture....Pages 61-67
Development of Biosynthesizing and Uptake Systems for Taurine in Cerebral Cortical Neurons in Primary Culture: Analysis of Possible Factors Involved in Perinatal Decline of Cerebral Taurine....Pages 69-77
Taurine Efflux from Brain Slices: Potassium-Evoked Release is Greater from Immature than Mature Brain Tissue....Pages 79-88
Taurine and Photoreceptor Structure: Biochemical and Electrophysiological Studies....Pages 89-99
Taurine Availability and Function in Neurogenetic Retinopathies....Pages 101-112
Nutritional Taurine Deficiency and Feline Pregnancy and Outcome....Pages 113-124
Abnormal Visual Acuity and Retinal Morphology in Rhesus Monkeys Fed a Taurine-Free Diet During the First Three Postnatal Months....Pages 125-134
Taurine Concentrations in Human Heart — A Retrospective Analysis....Pages 135-138
The Development of Heart and Brain Function in Low-Birth-Weight Infants Fed with Taurine-Supplemented Formula....Pages 139-145
Front Matter....Pages 147-147
Introduction: Pharmacology of Excitable Tissues....Pages 149-150
Potentiation of Myocardial Ischemic Injury by Drug-Induced Taurine Depletion....Pages 151-158
Inotropic Activity of Orthanilic and L-Cysteic Acid on Isolated Guinea-Pig Ventricular Strips....Pages 159-165
Calcium Overload-Induced Myocardial Damage Caused by Isoproterenol and by Adriamycin: Possible Role of Taurine in its Prevention....Pages 167-179
An Analysis of the Effects of Taurine on Cellular and Extracellular Calcium Mobilization in Rabbit Ear Artery....Pages 181-188
Suppression of Bronchial Response to Platelet Activating Factor Following Taurine Administration....Pages 189-198
Front Matter....Pages 147-147
Neural Regulation of Taurine Transport in Skeletal Muscle....Pages 199-205
Effect of Taurine on Chloride Conductance and Excitability of Rat Skeletal Muscle Fibers....Pages 207-216
Insulin-Like Activity of Taurine....Pages 217-226
Taurine Inhibits Wet-Dog Shakes and Hippocampal Seizures Induced by Opioid Peptides in Rats....Pages 227-235
Possible Involvement of Brain Calcium Metabolism in the Action of Taurine in Mammalian Thermoregulation....Pages 237-244
Front Matter....Pages 245-245
Introduction: Neurochemistry....Pages 247-252
A Taurine Receptor Model: Taurine-Sensitive Olfactory Cells in the Lobster....Pages 253-263
Taurine System in the Normal and Ischemic Rat Hippocampus....Pages 265-274
Immunocytochemical Demonstration of Taurine....Pages 275-284
Uptake, Localization and Release of Taurine in the Rat Basal Ganglia....Pages 285-294
Basal Concentration and Evoked Changes of Extracellular Taurine in the Rat Hippocampus in Vivo....Pages 295-305
A Model of the Compartmentalization of Taurine in Rat Hypothalamic Neuronal and Glial Cell Particles....Pages 307-317
Neurochemical Characterization of Excitatory Amino Acid Receptors in Hippocampus....Pages 319-324
The Effect of Taurine on Excitatory Receptor Binding in Rat Hippocampal Membranes....Pages 325-330
Taurine Deficiency in the Rat and Cat: Effects on Neurotoxic and Biochemical Actions of Kainate....Pages 331-339
Further Observation on the Interaction of Taurine and Calmodulin on the Central Adrenergic Neuron....Pages 341-346
Interactions of Taurine and Dopamine in the Striatum....Pages 347-355
Effects of Acidic Dipeptides on Aminoacidergic Neurotransmission in the Brain....Pages 357-368
Front Matter....Pages 369-369
From Heart to Hypothesis: A Mechanism for the Calcium Modulatory Actions of Taurine....Pages 371-387
Back Matter....Pages 389-404