The Bacteriology of Tuberculosis

CONTENTS......Page 10
Part One. Morphology and Cytology of the Tubercle Bacillus......Page 14
I. TUBERCLE BACILLUS AS A UNICELLULAR ORGANISM......Page 16
II. PHYSICAL METHODS IN IDENTIFYING CELL STRUCTURES......Page 21
III. BIOLOGICAL METHODS IN IDENTIFYING CELL STRUCTURES......Page 55
IV. CHEMICAL METHODS IN IDENTIFYING CELL STRUCTURES......Page 67
V. THE BACTERIAL CELL AND THE METAZOAN CELL......Page 79
Part Two. Sources of Energy and Growth of the Tubercle Bacillus......Page 88
VI. OXIDATION, FERMENTATION, AND GROWTH OF THE TUBERCLE BACILLUS......Page 90
VII. THE ACTION OF FATTY ACIDS, SALICYLATES, AND BENZOATES ON TUBERCLE BACILLI......Page 112
VIII. SOURCES OF CARBON......Page 128
IX. SOURCES OF NITROGEN AND PHOSPHORUS......Page 159
X. THE MINERAL REQUIREMENTS OF TUBERCLE BACILLI......Page 169
XI. GROWTH FACTORS AND TRACE ELEMENTS......Page 173
Part Three. The Isolation and Identification of the Tubercle Bacillus......Page 182
XII. THE COLLECTION OF TUBERCULOUS MATERIAL......Page 184
XIII. DIAGNOSTIC STAINING OF TUBERCLE BACILLI......Page 198
XIV. FLUORESCENCE AND PHASE CONTRAST MICROSCOPY AS DIAGNOSTIC PROCEDURES......Page 204
XV. CULTIVATION OF TUBERCLE BACILLI......Page 207
XVI. THE SHAKING-PRECIPITATION (SP) METHOD......Page 226
XVII. SUBMERGED GROWTH......Page 242
XVIII. DISPERSED GROWTH......Page 249
XIX. EFFICACY OF MICROSCOPIC EXAMINATION, CULTURE, AND ANIMAL INOCULATION......Page 268
XX. QUANTITATIVE ASPECTS OF TUBERCLE BACILLI IN SPUTUM......Page 277
Part Four. The Types and Pathogenicity of the Tubercle Bacillus......Page 284
XXI. DO FIXED TYPES OF TUBERCLE BACILLI EXIST?......Page 286
XXII. METHODS OF DETERMINING VIRULENCE......Page 300
Part Five. Experimenting with the Tubercle Bacillus......Page 328
XXIII. PROBLEMS IN EXPERIMENTING WITH TUBERCLE BACILLI......Page 330
XXIV. ESTIMATING THE ANTITUBERCULOUS ACTIVITY OF A NEW DRUG......Page 335
XXV. THE GUINEA PIG IN EXPERIMENTAL TUBERCULOSIS......Page 340
XXVI. THE RABBIT IN EXPERIMENTAL TUBERCULOSIS......Page 346
XXVII. THE MOUSE IN EXPERIMENTAL TUBERCULOSIS......Page 353
XXVIII. THE HAMSTER IN EXPERIMENTAL TUBERCULOSIS......Page 370
XXIX. CHORIOALLANTOIC MEMBRANE AND CHICK EMBRYO IN EXPERIMENTAL TUBERCULOSIS......Page 376
XXX. HAZARDS AND PRECAUTIONS IN THE LABORATORY......Page 395
BIBLIOGRAPHY......Page 416
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I......Page 479
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