Textbook of Autoinflammation

Front Matter ....Pages i-x
Front Matter ....Pages 1-1
 Autoinflammation: Past, Present, and Future  (Daniel L. Kastner)....Pages 3-15
Front Matter ....Pages 17-17
 Genetic Aspects of Investigating and Understanding Autoinflammation  (Isabella Ceccherini, Marta Rusmini, Juan Ignacio Arostegui)....Pages 19-48
 Epigenetics in Autoinflammation  (Clara Lorente-Sorolla, Mihai G. Netea, Esteban Ballestar)....Pages 49-60
 Pattern Recognition Receptors in Autoinflammation  (Victor Saavedra, Fiona Moghaddas, Eicke Latz, Seth L. Masters)....Pages 61-87
 Inflammasomes and Autoinflammation  (Lori Broderick)....Pages 89-109
 Cytokines in Autoinflammation  (Angela Rösen-Wolff, Anna Rubartelli)....Pages 111-122
 Proteasomes in Autoinflammation  (Anja Brehm, Frédéric Ebstein, Elke Krüger)....Pages 123-136
 Disruption of Protein Homeostasis and Activation of Cellular Stress Pathways in Autoinflammation  (Cornelia D. Cudrici, Richard M. Siegel)....Pages 137-147
 S100 Proteins in Autoinflammation  (Dirk Holzinger, Christoph Kessel, Dirk Foell)....Pages 149-163
Front Matter ....Pages 165-165
 Classification of Genetically Defined Autoinflammatory Diseases  (Raphaela Goldbach-Mansky, Adriana A. de Jesus)....Pages 167-201
 Clinical Approach to the Diagnosis of Autoinflammatory Diseases  (Philip J. Hashkes, Karyl S. Barron, Ronald M. Laxer)....Pages 203-223
 Genetic Approach to the Diagnosis of Autoinflammatory Diseases  (Isabelle Touitou, Ivona Aksentijevich)....Pages 225-237
 Monitoring Disease Activity, Damage and Quality of Life  (Nienke ter Haar, Maryam Piram, Isabelle Koné-Paut)....Pages 239-252
 The Role of International Registries for Rare Autoinflammatory Diseases  (Martina Finetti, Marco Gattorno)....Pages 253-265
 Systemic Amyloidosis  (Tamer Rezk, Philip N. Hawkins)....Pages 267-289
Front Matter ....Pages 291-291
 Familial Mediterranean Fever  (Shai Padeh, Yelda Bilginer, Seza Ozen)....Pages 293-313
 Mevalonate Kinase Deficiency  (Joost Frenkel, Anna Simon)....Pages 315-327
 Tumor Necrosis Factor (TNF) Receptor-Associated Periodic Syndrome (TRAPS)  (Sinisa Savic, Michael F. McDermott)....Pages 329-345
 Cryopyrin-Associated Periodic Syndromes (CAPS)  (Hal M. Hoffman, Jasmin B. Kuemmerle-Deschner, Raphaela Goldbach-Mansky)....Pages 347-365
 Autoinflammatory Granulomatous Disease: Blau Syndrome  (Carlos D. Rose, Carine H. Wouters)....Pages 367-381
 Very Early Onset Inflammatory Bowel Disease (VEOIBD)  (Aleixo M. Muise)....Pages 383-404
 Pyogenic Arthritis Pyoderma Gangrenosum and Acne (PAPA) Syndrome  (Marilynn G. Punaro, Carol A. Wise)....Pages 405-415
 Deficiency of Adenosine Deaminase 2 (DADA2)  (Amanda Ombrello, Reeval Segel)....Pages 417-431
 Genetic Interferonopathies  (Despina Eleftheriou, Antonio Torrelo, Paul A. Brogan)....Pages 433-453
 Genetic Causes of Inflammatory Bone Disease  (James Verbsky, Polly J. Ferguson)....Pages 455-470
 Pustular Forms of Psoriasis Related to Autoinflammation  (Satveer K. Mahil, Jonathan N. Barker, Francesca Capon)....Pages 471-484
 Hydatidiform Moles  (Ngoc Minh Phuong Nguyen, Pierre-Adrien Bolze, Rima Slim)....Pages 485-497
 Monogenic Autoinflammatory Diseases Associated with Immunodeficiency  (Michael J. Ombrello)....Pages 499-514
 Other Rare Monogenic Autoinflammatory Diseases  (Isabelle Jéru, Scott W. Canna, Eric P. Hanson)....Pages 515-538
Front Matter ....Pages 539-539
 Periodic Fever, Aphthous Stomatitis, Pharyngitis and Cervical Adenitis (PFAPA) Syndrome  (Kathryn M. Edwards, Michael Hofer)....Pages 541-561
 Chronic Non-Bacterial Osteomyelitis  (Christian M. Hedrich, Hermann J. Girschick)....Pages 563-585
 Systemic Juvenile Idiopathic Arthritis and Adult Onset Still Disease  (Peter A. Nigrovic, Rayfel Schneider)....Pages 587-616
 Macrophage Activation Syndrome in Rheumatic Diseases  (Alexei A. Grom, Edward M. Behrens)....Pages 617-633
 Gouty Inflammation  (Naomi Schlesinger, Johnson C. Kay)....Pages 635-645
 Behçet Disease  (Ahmet Gül)....Pages 647-665
 Idiopathic Recurrent Pericarditis  (Massimo Imazio, Anna Valenti, Antonio Brucato, Alberto Martini)....Pages 667-677
 Schnitzler Syndrome  (Heleen D. de Koning, Karoline Krause)....Pages 679-689
Front Matter ....Pages 691-691
 Autoinflammation and Autoimmunity  (Dennis McGonagle, Abdulla Watad)....Pages 693-710
 Interleukin-1 Mediated Autoinflammation from Heart Disease to Cancer  (Charles A. Dinarello)....Pages 711-725
Front Matter ....Pages 727-727
 Colchicine  (Eldad Ben-Chetrit)....Pages 729-749
 Interleukin (IL)-1 Blocking Compounds and Their Use in Autoinflammatory Diseases  (Tilmann Kallinich, Fabrizio de Benedetti)....Pages 751-774
 Corticosteroid, Other Biologic and Small Molecule Therapies in Systemic Autoinflammatory Disorders  (Helen J. Lachmann)....Pages 775-791
Back Matter ....Pages 793-820