T Lymphocytes: Structure, Functions, Choices

Front Matter....Pages i-xi
T-Cell Antigen and MHC Recognition: Molecular Analysis of Human α/β TCR Specific for a Tetanus Toxin-Derived Peptide....Pages 1-16
Structure of the TCR-Ag-MHC Complex....Pages 17-23
Is Recognition by the T Cell Receptor Highly Constrained or Very Degenerate?....Pages 25-35
Characteristics of Foreign and Self Peptides Endogenously Bound to MHC Class I Molecules....Pages 37-43
Positive and Negative Selection of T Cells....Pages 45-60
Peripheral Tolerance....Pages 61-69
The Functional Relationship between Preferential Use of Newly Synthesized Class II Molecules and Their Stable Association with Peptides....Pages 71-74
Epitope Selection and Autoimmunity....Pages 75-87
HLA-A2 Allorecognition and Subtype Diversification....Pages 89-95
On the Antigenicity of Antibody Idiotypes....Pages 97-104
Idiotype Interactions between T Cells....Pages 105-110
A Network of Self Interactions....Pages 111-120
Stimulation of Lymphocytes by Anti-Idiotypes Bearing the Internal Image of Viral Antigens....Pages 121-133
Cloned Suppressor T Cells --- Their Identity, Functions, and Mediators....Pages 135-144
The Autoreactive T Cell Receptor: Structure and Biological Activity....Pages 145-151
The Relationship between Diabetes and Lymphopenia in the BB Rat....Pages 153-161
RT6, an Unusually Polymorphic T-Cell Specific Membrane Protein Linked to Type I Autoimmune Diabetes in Rats and Mice....Pages 163-167
Alternative Pathways of Signal Transduction after Ligation of the TCR by Bacterial Superantigen....Pages 169-177
Molecular Analysis of the Interactions between Staphylococcal Enterotoxin a Superantigen and the Human MHC Class II Molecules....Pages 179-185
Immunosuppression by MHC Class II Blockade....Pages 187-194
Recognition of HIV Antigens by Human T Helper Cells....Pages 195-205
Proliferative Responses to the V3 Region of HIV Envelope Are Enhanced Following Immunization with V3:Ty Virus-Like Particles in Mice....Pages 207-214
Teaching Immunology: A Montessori Approach using a Computer Model of the Immune System....Pages 215-225
Modelling T Cell Memory in Vivo and in Vitro....Pages 227-234
Oligoclonal T Cells Expressing the TCR V-ß 6 Gene Product Following IL-2 Culture of Ovarian Carcinoma Derived Lymphocytes....Pages 235-240
Comparisons of the V-Delta-1 Expressing T-Cells in Synovial Fluid and Peripheral Blood of Patients with Chronic Arthritis....Pages 241-246
Bispecific Monoclonal Antibody Targeted Cytotoxic T Lymphocytes can Recycle....Pages 247-249
Back Matter....Pages 251-256