SUMO Regulation of Cellular Processes

Front Matter....Pages i-ix
Front Matter....Pages 11-11
Introduction to Sumoylation....Pages 1-10
SUMO Modification and Transcriptional Regulation....Pages 13-40
Emerging Roles for SUMO in mRNA Processing and Metabolism....Pages 41-57
SUMO and Chromatin Remodelling....Pages 59-76
Functions of SUMO in the Maintenance of Genome Stability....Pages 77-96
SUMO and Nucleocytoplasmic Transport....Pages 97-116
SUMO Modification of Ion Channels....Pages 117-136
The Roles of SUMO in Metabolic Regulation....Pages 137-149
Front Matter....Pages 151-151
The SUMO Pathway in Mitosis....Pages 153-169
Wrestling with Chromosomes: The Roles of SUMO During Meiosis....Pages 171-185
Sumoylation in Development and Differentiation....Pages 187-199
The Role of Sumoylation in Senescence....Pages 201-216
Sumoylation and Apoptosis....Pages 217-230
Front Matter....Pages 231-231
The Role of Sumoylation in Neurodegenerative Diseases....Pages 233-251
Sumoylation and Its Contribution to Cancer....Pages 253-272
SUMO4-Encoded Genetic Susceptibility to Type 1 Diabetes....Pages 273-299
Sumoylation in Craniofacial Disorders....Pages 301-313
Viral Interplay with the Host Sumoylation System....Pages 315-329
Back Matter....Pages 331-339