Structure, Dynamics and Function of Biomolecules: The First EBSA Workshop A Marcus Wallenberg Symposium

Front Matter....Pages I-XVI
The Nature of Mechanical Devices in Biological Systems....Pages 1-4
Physical Chemistry and Biological Strategy of Antigen Recognition....Pages 5-9
Heme Protein Reactions: Models, Concepts, and Problems....Pages 10-14
Multiple Conformational States of Myoglobin: A Molecular Dynamics Analysis....Pages 15-19
Dynamics of Structural Changes in Hemoglobin....Pages 20-24
Structure and Dynamics of Photodissociated Myoglobin....Pages 25-29
Structural Fluctuations in Myoglobin....Pages 30-33
Glass Transition of Hydration Water and Structural Flexibility of Myoglobin....Pages 34-38
Pressure Studies of Large-Scale Protein Motions....Pages 39-42
Viscosity and Glycerol Effects on Dynamics of Cytochrome c....Pages 43-46
Kinetics of Geminate Recombination Following Photodissociation of Mutant (Carbonmonoxy)Hemoglobins....Pages 47-50
Thermodynamics of Enzyme Folding and Activity: Theory and Experiment....Pages 51-55
Progress and Problems in the Study of Protein Dynamics by X-Ray Diffraction....Pages 56-60
Activation Free Energies of Enzymatic Reactions; Simulations and Experiments....Pages 61-64
Simple Models for the Dynamics of Biomolecules: How Far Can We Go?....Pages 65-69
Condensed Matter Biophysics: Structure and Dynamics of Large Biomolecules....Pages 70-74
Molecular Dynamics Simulation of Parvalbumin in Aqueous Solution....Pages 75-81
Cooperative Ion Binding to Proteins. A Statistical Mechanical Approach....Pages 82-85
Single Step Kinetics of Enzyme Dynamics....Pages 86-92
Low Frequency Dynamics of BPTI Studied by Inelastic Neutron Scattering....Pages 93-97
Trans-Cis Isomerizations in Biology....Pages 98-103
A NMR View of Proteins in Solution....Pages 104-107
Determination of 3D-Structures of Macromolecules by Restrained Molecular Dynamics on the Basis of Interproton Distances....Pages 108-112
The Structure of the tRNA Anticodon Arm as Determined by Restrained Molecular Dynamics in Combination with NMR Interproton Distance Data....Pages 113-117
Solving Solution Structural Problems by Combining 2-D NMR Data with Known Substructures from a Protein Database....Pages 118-121
Molecular Graphics and Molecular Dynamics....Pages 122-126
Study of the Dynamics of Hydrated Proteins and Protein-Bound Water by Rayleigh Scattering of Mössbauer Radiation (RSMR)....Pages 127-131
Fluorescence Lifetime Distributions of Single Tryptophan Proteins: A Protein Dynamics Approach....Pages 132-135
Time Domain Spectroscopy of Molecular Dynamics....Pages 136-139
Detection of Time-Resolved Microsecond Molecular Dynamics by Optical and Magnetic Resonance Spectroscopy....Pages 140-144
Linear Dichroism — A Potential Method for Studying DNA-Protein Interaction....Pages 145-147
Microtubule Structure and Assembly Studied by Time-Resolved X-Ray Scattering and Cryo-Electron Microscopy....Pages 148-151
Polymerisation of Fibrinogen to Fibrin Studied by Time-Resolved Small Angle Neutron Scattering....Pages 152-158
Internal Dynamics of Aromatic Residues in Subtilisin BPN’ and Subtilisin Carlsberg : Time-Resolved Fluorescence Properties....Pages 159-164
Time-Resolved Fluorescence Anisotropy Decay Studies in Proteins....Pages 165-170
Study of Single Cycles of the Direct and Back Enzyme Reactions Catalyzed by Malatedehydrogenase....Pages 171-175
Dynamics of Iron in Ferritin....Pages 176-179
Structure, Dynamics and Function of Serine Proteases....Pages 180-182
Intramolecular Proton Transfer in Bacteriorhodopsin (bR)....Pages 183-186
ATP Synthesis by the Membrane Bound and Isolated H + ATPases After Jump-Like pH Increase....Pages 187-190
Structural Aspects on Energy Transfer in Light-Harvesting Complexes....Pages 191-195
Imino-Proton Exchange and Base-Pair Kinetics of Nucleic Acids....Pages 196-200
NMR and Time Resolved Fluorescence Studies of a 2-Aminopurine Substituted Eco RI Restriction Site....Pages 201-207
Local Flexibility in Recognition Processes Between Macromolecules....Pages 208-211
Conformational Aspects of Hairpin Loops in DNA Oligonucleotides....Pages 212-216
The Cruciform Extrusion Transition in Supercoiled DNA Molecules....Pages 217-223
Left-Handed DNA: Energetic and Dynamic Aspects....Pages 224-228
Z-DNA Dynamic Structure: A Hydrogen Exchange Study....Pages 229-233
Induction of the Z Conformation in DNAs Studied by I.R. Spectroscopy....Pages 234-237
The B → Z Transition in Poly[d(G-C)·d(G-C)] After Covalent Binding of Anti -Benzo(a)Pyrenediolepoxide....Pages 238-241
Effects of Hydration on the DNA Base Motion....Pages 242-246
Structure and Dynamics of DNA and DNA-Adduct Complexes Studied with Polarized Light Spectroscopy....Pages 247-250
Calculation of Electrostatic Interactions Between Hexagonally Oriented DNA-Molecules....Pages 251-254
Structure of the DNA-EcoRI Endonuclease Recognition Complex....Pages 255-259
Ribonuclease T1: Interaction with 2’GMP and 3’GMP as Studied by Time-Resolved Fluorescence Spectroscopy....Pages 260-265
Ultrasonic Absorption Evidence for Enhanced Volume Fluctuations in the Tobacco-Mosaic-Virus-Protein Helical Aggregate....Pages 266-269
3-D Image Reconstruction of a Specific Premessenger RNP Particle....Pages 270-274
Molecular Dynamics of a Bilayer Membrane with Atomic Detail....Pages 275-280
Time-Resolved X-Ray Diffraction on Lipid Bilayer Interactions Using Synchrotron Radiation....Pages 281-284
Molecular Dynamics Studies of Model Membranes with Alfa Helices....Pages 285-288
Orientational Fluctuations of Melittin in Lipid Membranes as Detected by Time-Resolved Fluorescence Anisotropy Measurements....Pages 289-294
Structure Predictions for Membrane Proteins....Pages 295-298
The Temperature Peaks of Cell Membrane Permeability....Pages 299-302
Back Matter....Pages 303-303