Solid-Phase Peptide Synthesis

Content: 
Contributors to volume 289
Pages ix-xi

Preface
Page xiii
Gregg B. Fields

Volumes in series
Pages xv-xxxi

[1] Concept and early development of solid-phase peptide synthesis Original Research Article
Pages 3-13
Bruce Merrifield

[2] Rapid in situ neutralization protocols for Boc and Fmoc solid-phase chemistries Original Research Article
Pages 14-29
Paul Alewood, Dianne Alewood, Les Miranda, Stephen Love, Wim Meutermans, David Wilson

[3] Cleavage methods following Boc-based solid-phase peptide synthesis Original Research Article
Pages 29-44
John M. Stewart

[4] Standard Fmoc protocols Original Research Article
Pages 44-67
Donald A. Wellings, Eric Atherton

[5] Trifluoroacetic acid cleavage and deprotection of resin-bound peptides following synthesis by Fmoc chemistry Original Research Article
Pages 67-83
Cynthia A. Guy, Gregg B. Fields

[6] Properties of solid supports Original Research Article
Pages 83-104
Morten Meldal

[7] Coupling reagents and activation Original Research Article
Pages 104-126
Fernando Albericio, Louis A. Carpino

[8] Handles for solid-phase peptide synthesis Original Research Article
Pages 126-174
Michael F. Songster, George Barany

[9] Solid-phase synthesis of cyclic homodetic peptides Original Research Article
Pages 175-198
Christopher Blackburn, Steven A. Kates

[10] Disulfide bond formation in peptides Original Research Article
Pages 198-221
Ioana Annis, Balazs Hargittai, George Barany

[11] Direct synthesis of glycosylated amino acids from carbohydrate peracetates and Fmoc amino acids: Solid-phase synthesis of biomedicinally interesting glycopeptides Original Research Article
Pages 221-245
Jan Kihlberg, Mikael Elofsson, Lourdes A. Salvador

[12] Synthesis of phosphopeptides using modern chemical approaches Original Research Article
Pages 245-266
John William Perich

[13] Protein synthesis by chemical ligation of unprotected peptides in aqueous solution Original Research Article
Pages 266-298
Tom W. Muir, Philip E. Dawson, Stephen B.H. Kent

[14] Synthesis of proteins by subtiligase Original Research Article
Pages 298-313
Andrew C. Braisted, J. Kevin Judice, James A. Wells

[15] Convergent solid-phase peptide synthesis Original Research Article
Pages 313-336
Fernando Albericio, Paul Lloyd-Williams, Ernest Giralt

[16] Synthetic peptide libraries Original Research Article
Pages 336-392
Michal Lebl, Viktor KrchnГЎk

[17] Edman sequencing as tool for characterization of synthetic peptides Original Research Article
Pages 395-419
Gregory A. Grant, Mark W. Crankshaw, John Gorka

[18] Amino acid analysis Original Research Article
Pages 419-426
Alan J. Smith

[19] Analysis of synthetic peptides by high-performance liquid chromatography Original Research Article
Pages 426-469
Colin T. Mant, Leslie H. Kondejewski, Paul J. Cachia, Oscar D. Monera, Robert S. Hodges

[20] Capillary electrophoresis Original Research Article
Pages 469-478
Agustin Sanchez, Alan J. Smith

[21] Fast atom bombardment mass spectrometry of synthetic peptides Original Research Article
Pages 478-499
Е ГЎrka BeranovГЎ-Giorgianni, Dominic M. Desiderio

[22] Analysis of peptide synthesis products by electrospray ionization mass spectrometry Original Research Article
Pages 499-519
Daniel J. Burdick, John T. Stults

[23] Laser desorption mass spectrometry Original Research Article
Pages 520-542
William T. Moore

[24] Protein signature analysis: A practical new approach for studying structure-activity relationships in peptides and proteins Original Research Article
Pages 545-564
Tom W. Muir, Philip E. Dawson, Michael C. Fitzgerald, Stephen B.H. Kent

[25] In vitro incorporation of synthetic peptides into cells Original Research Article
Pages 564-571
Janelle L. Lauer, Gregg B. Fields

[26] Construction of biologically active protein molecular architecture using self-assembling peptide-amphiphiles Original Research Article
Pages 571-582,IN1-IN2,583-587
Ying-Ching Yu, Teika Pakalns, Yoav Dori, James B. McCarthy, Matthew Tirrell, Gregg B. Fields

[27] Chemical synthesis and nuclear magnetic resonance characterization of partially folded proteins Original Research Article
Pages 587-611
Elisar Barbar, Christopher M. Gross, Clare Woodward, George Barany

[28] Multiple antigen peptide system Original Research Article
Pages 612-637
James P. Tam, Jane C. Spetzler

[29] Relaxin Original Research Article
Pages 637-646
John D. Wade, Geoffrey W. Tregear

[30] Solution nuclear magnetic resonance characterization of peptide folding Original Research Article
Pages 646-672
Kevin H. Mayo

[31] Solid-state nuclear magnetic resonance characterization of gramicidin channel structure Original Research Article
Pages 672-696,IN3-IN4
T.A. Cross

[32] Six-year study of peptide synthesis Original Research Article
Pages 697-717
Ruth Hogue Angeletti, Lynda F. Bonewald, Gregg B. Fields

Author index
Pages 719-761

Subject index
Pages 763-780