Social Cognition in Psychosis

Cover
SOCIAL COGNITION
IN PSYCHOSIS
Copyright
Dedication
Contributors
Preface
Acknowledgement
Editors biography
1
Characterization of social cognitive deficits on the schizophrenia-bipolar disorder spectrum: An overview of ...
	Introduction
	Early course Sz-spectrum disorders
		Ultra high risk for psychosis
			Emotion processing
			Theory of mind
			Social perception and attributional style
		First-episode psychosis
			Emotion processing
			Theory of mind
			Social perception
			Attributional style
	Established Sz-spectrum disorders
		Emotion processing
		Theory of mind
		Social perception
		Attributional style
	Pediatric and early course BD
		Emotion processing
		Theory of mind
	Established BD
		Emotion processing
		Theory of mind
		Attributional style
	Conclusions
	References
2
Cognitive and social cognitive deficits in paranoia
	The definition of paranoia and persecutory ideation
	The development of paranoid thinking
	Fundamental cognitive processes and social cognition in paranoia
		Jumping to conclusions
		Aberrant salience and sensitivity to social threat
		Attachment and the self
		Theory of mind and attribution
		Game theoretic approaches to social cognition and behavior in paranoia
	Acknowledgments
	References
3
Social cognition and schizotypy
	Definitions and grounding
		Schizotypy
		Social cognition
	What is known about social cognition in schizotypy?
		Social perception
		Mentalizing and ToM
		Experience sharing and empathy
		Self-awareness
		Attributional style
		Social knowledge
	What are potential mechanisms/causes of social cognitive abnormalities in schizotypy?
		Psychophysiological mechanisms
		Nonsocial cognition as a mechanism
		Directionality of social cognition and schizotypy
	Summary and conclusion
	References
	Further Reading
4
Impact of social cognitive deficits on community functioning
	Introduction
	Community functioning in schizophrenia
		Independent living
		Social functioning
		Work functioning
	Factors affecting community functioning in schizophrenia
		Impact of social cognitive deficits on competence and real world behavior in schizophrenia
	Impact of social cognitive domains on community functioning in schizophrenia
		Theory of Mind
		Emotion processing
		Empathy
		Attributional style
		Social perception
		Conclusions
	Patients at UHR for psychosis: Clinical features and community functioning
		Predictors of community functioning in UHR subjects
	First-episode psychosis: Social cognitive and functional features
		Impact of social cognitive deficits on community functioning in FEP patients
	Bipolar disorder: Clinical features and functional outcomes
		Social cognition and community outcomes in BD
	Conclusions
	References
5
Shared neural substrates of deficits in social cognition and negative symptoms in schizophrenia
	A bottom-up model
	Top-down model
	Integrated model
	The role of negative affect and dysfunctional attitudes
	Conclusions and future directions
	References
6
Role of oxytocin in social cognition in psychosis spectrum disorders
	Oxytocin and social cognition
		Biology and mechanism
		Oxytocinergic abnormalities in schizophrenia spectrum and bipolar disorders
		Clinical trials of exogenous oxytocin in SZ
		Clinical trials of exogenous oxytocin in SPD/schizotypy/genetic risk/clinical high risk
		Clinical trials combining intranasal oxytocin and psychotherapy/cognitive behavioral interventions
	References
7
Reward processing and social functioning in psychosis
	Motivation and reward processing: Wanting, liking, and learning
	Reward-processing abnormalities in psychosis
		Abnormalities in reward ``wanting´´ in psychosis
		Intact reward ``liking´´ in psychosis
		Impairments in some, but not all forms of reward-learning in psychosis
	Links between reward processing and social behavior
	The neurobiology of reward processing
	Evidence for mesolimbic dopamine reward system disruption in psychosis
	The role of dopamine reward pathways in social functioning
	Links between aberrant reward circuit functioning and social deficits in psychosis
	Are abnormalities in reward processing a cause of impaired social functioning in psychosis?
	Future directions
	References
8
Substance misuse and social cognition on the psychosis-spectrum: A bottom-up framework
	Introduction
	Direct links between substance use and social cognition in psychotic disorders
		Tobacco and social cognition
		Ketamine and social cognition
		Alcohol and social cognition
		Cannabis and social cognition
		Amphetamines and social cognition
	Indirect links between substance misuse and social cognition
		The impact of substance use on preattentional functioning, and links with social cognition
		Mismatch negativity and related components
			Cannabis and preattentional functioning
			Ketamine and preattentional functioning
			Alcohol and preattentional functioning
		The impact of substance use on heart rate variability and links to social cognition
	Concluding remarks and future directions
	References
9
Assessment of social cognition
	Shared challenges of assessment: Neurocognition and social cognition
	Challenges in social cognitive measurement
	Social Cognition Psychometric Evaluation: An overview
	Social Cognition Psychometric Evaluation: Results
	Measures suitable for immediate use in clinical trials
		The Bell Lysaker Emotion Recognition Task (Bryson et al., 1997)
		The hinting task (hinting) (Corcoran et al., 1995)
		The Penn Emotion Recognition Task (Kohler et al., 2003)
	Measures showing adequate psychometric properties, but with limitations
		Reading the Mind in the Eyes test (Baron-Cohen et al., 2001)
		The Awareness of Social Inferences Test, part III (McDonald et al., 2003)
		The Intentional Bias Task (Rosset, 2008)
	Extension of Social Cognition Psychometric Evaluation: Informant rating measures of social cognition
	Implication of Social Cognition Psychometric Evaluation results
	Social cognitive assessments and functional outcomes
	Social competence assessments
	Social skills performance assessment
	The importance of reduced social motivation on social outcomes
	Other considerations: Social cognition in other psychiatric conditions
	Future research areas
	Summary
	References
10
Improving ecological validity in research on social cognition
	Social cognition: A prerequisite for social functioning?
	Ecological validity
	Virtual reality
	Experience sampling methodology
	Conclusion and implications
	References
11
Social cognitive interventions
	Origins of social cognitive interventions
	Proof of concept
		Social perception
		ToM/attributional bias
		Emotion perception
	Targeted single-domain interventions
		Emotion perception
		Social perception/knowledge
		ToM/attributional bias
	Comprehensive, multidomain interventions
		Social Cognition Interaction Training
		Social Cognitive Skill Training
		Computerized comprehensive social cognitive interventions
	Discussion and conclusions
	References
12
Psychosocial interventions for social dysfunction in psychosis
	Early interventions for social deficits in psychosis
		Social skills deficits and training
		Social motivation and reward
			Therapeutic communities and milieu therapy
			Group therapy
	Psychosocial interventions that target social cognition and/or social functioning directly: Targets and outcomes
		Integrated Psychological Therapy
		Cognitive Enhancement Therapy
		Neuropsychological Educational Approach to Remediation
		Functional Remediation
		Neurocognitive Enhancement Therapy
		Combined theory of mind and cognitive remediation therapy
		Cognitive Adaptation Training
		Cognitive Behavioral Social Skills Training
		Functional Adaptation Skills Training
		Metacognitive training
	Summary, limitations, and future directions
		Summary
		Limitations
		Future directions
	References
Index
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	D
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	H
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