Sleep Medicine

0195129571......Page 1
CONTENTS......Page 12
Part 1. Sleep......Page 26
HISTORY......Page 28
SLEEP RECORDINGS......Page 32
SLEEP STAGES......Page 34
CLINICAL FEATURES OF SLEEP......Page 40
PHYSIOLOGIC CHANGES DURING SLEEP......Page 42
FUNCTIONS OF SLEEP......Page 45
SLEEP-WAKE REGULATION......Page 52
NREM SLEEP......Page 55
REM SLEEP......Page 57
SLEEP FACTORS......Page 59
THE RESPIRATORY CONTROL SYSTEM......Page 64
SLEEP-RELATED CHANGES IN BREATHING......Page 75
4. CHRONOBIOLOGY......Page 81
PHYSIOLOGIC FUNCTIONS WITH CIRCADIAN RHYTHMICITY......Page 82
NEUROANATOMY OF THE CIRCADIAN TIMING SYSTEM......Page 83
FACTORS AFFECTING CLOCK FUNCTION......Page 84
ZEITGEBERS, MASKING STIMULI, AND RHYTHM  INTERACTIONS......Page 86
EFFECTS OF THE CIRCADIAN PACEMAKER ON SLEEP  AND WAKEFULNESS......Page 87
DIFFERENTIATION OF STATES OF SLEEP AND  WAKEFULNESS......Page 95
EVOLUTION OF SLEEP-WAKE CYCLES AND  ELECTROENCEPHALOGRAPHIC PATTERNS AFTER BIRTH......Page 97
AGE-RELATED CHANGES IN RESPIRATION......Page 102
MOVEMENTS DURING SLEEP OVER THE LIFE SPAN......Page 105
DREAMS THROUGHOUT HISTORY......Page 107
DREAMS COMPARED TO OTHER MENTAL ACTIVITY OF SLEEP......Page 108
PSYCHOPHYSIOLOGY OF REM SLEEP AND DREAMING......Page 110
DREAM CONTENT......Page 111
FACTORS INFLUENCING DREAM RECALL......Page 112
PSYCHOLOGICAL ASPECTS OF DREAMS......Page 113
Part 2. Sleep Disorders......Page 118
THE DEVELOPMENT OF SLEEP MEDICINE......Page 120
CLASSIFICATION OF SLEEP DISORDERS......Page 121
EVALUATION OF THE PATIENT......Page 123
DIAGNOSTIC PROCEDURES......Page 129
MANAGEMENT......Page 133
8. SLEEPINESS AND SLEEP DEPRIVATION......Page 136
SLEEPINESS......Page 137
TOTAL SLEEP DEPRIVATION......Page 143
INSUFFICIENT SLEEP SYNDROME......Page 145
9. INSOMNIA......Page 152
CLINICAL FEATURES......Page 153
EPIDEMIOLOGY......Page 154
PSYCHOBIOLOGIC BASIS......Page 155
HYPNOTIC MEDICATIONS......Page 158
DIFFERENTIAL DIAGNOSIS......Page 161
PSYCHOPHYSIOLOGIC INSOMNIA......Page 164
SLEEP-STATE MISPERCEPTION (PSEUDOINSOMNIA)......Page 167
EXTRINSIC SLEEP DISORDERS THAT CAUSE INSOMNIA......Page 169
10. NARCOLEPSY AND RELATED DISORDERS......Page 177
CLINICAL FEATURES......Page 178
BIOLOGIC BASIS......Page 182
CLINICAL VARIANTS AND RELATED DISORDERS......Page 186
DIFFERENTIAL DIAGNOSIS......Page 191
DIAGNOSTIC EVALUATION......Page 192
MANAGEMENT......Page 194
11. RESTLESS LEGS SYNDROME AND PERIODIC LIMB MOVEMENT DISORDER......Page 200
RESTLESS LEGS SYNDROME......Page 201
PERIODIC LIMB MOVEMENT DISORDER......Page 206
JET LAG......Page 211
SHIFT-WORK SLEEP DISORDER......Page 214
DELAYED SLEEP PHASE SYNDROME......Page 217
IRREGULAR SLEEP-WAKE PATTERN......Page 220
NON–24-HOUR SLEEP-WAKE SYNDROME......Page 222
13. OBSTRUCTIVE SLEEP APNEA SYNDROME......Page 227
CLINICAL FEATURES......Page 228
EPIDEMIOLOGY......Page 231
BIOLOGIC BASIS......Page 232
SYSTEMIC EFFECTS OF OBSTRUCTIVE SLEEP APNEA......Page 242
COMPLICATIONS......Page 245
DIAGNOSTIC EVALUATION......Page 247
MANAGEMENT......Page 250
14. CENTRAL SLEEP APNEA AND HYPOVENTILATION DURING SLEEP......Page 262
CENTRAL SLEEP APNEA......Page 263
SUDDEN INFANT DEATH SYNDROME......Page 274
CENTRAL ALVEOLAR HYPOVENTILATION SYNDROME......Page 276
OBESITY-HYPOVENTILATION SYNDROME......Page 277
HYPOVENTILATION ASSOCIATED WITH NEUROMUSCULAR DISORDERS......Page 278
15. PARASOMNIAS......Page 285
AROUSAL DISORDERS......Page 286
SLEEP-WAKE TRANSITION DISORDERS......Page 292
PARASOMNIAS RELATED TO REM SLEEP......Page 295
OTHER PARASOMNIAS......Page 304
SLEEP DISORDERS ASSOCIATED WITH SCHIZOPHRENIA......Page 313
SLEEP DISTURBANCE ASSOCIATED WITH MOOD DISORDERS......Page 315
SLEEP DISORDERS ASSOCIATED WITH ANXIETY DISORDERS......Page 322
SLEEP DISTURBANCE ASSOCIATED WITH EATING DISORDERS......Page 324
SLEEP DISTURBANCE ASSOCIATED WITH ALCOHOL USE AND ALCOHOLISM......Page 325
SLEEP DISTURBANCE ASSOCIATED WITH OTHER SUBSTANCE-RELATED DISORDERS......Page 328
SLEEP DISTURBANCE IN ISCHEMIC HEART DISEASE......Page 332
SLEEP DISTURBANCE IN CHRONIC LUNG DISEASES......Page 337
SLEEP DISTURBANCE AND GASTROINTESTINAL DISEASE......Page 339
SLEEP DISTURBANCE AND RHEUMATOLOGIC DISORDERS......Page 342
SLEEP DISTURBANCE AND CHRONIC RENAL FAILURE......Page 345
ALZHEIMER'S DISEASE AND SLEEP DISTURBANCE......Page 350
PARKINSON'S DISEASE AND SLEEP DISTURBANCE......Page 354
PROGRESSIVE SUPRANUCLEAR PALSY AND SLEEP DISTURBANCE......Page 357
SLEEP DISTURBANCE IN DISORDERS WITH MULTI-SYSTEM DEGENERATION......Page 359
ENCEPHALITIS LETHARGICA......Page 363
SLEEPING SICKNESS......Page 364
FATAL FAMILIAL INSOMNIA......Page 365
PRADER-WILLI SYNDROME......Page 366
KLEINE-LEVIN SYNDROME......Page 367
IDIOPATHIC RECURRING STUPOR......Page 369
OTHER DIENCEPHALIC AND BRAINSTEM DISTURBANCES......Page 370
OVERVIEW OF EPILEPSY......Page 375
SLEEP AND EPILEPTIC MANIFESTATIONS......Page 377
DIAGNOSIS OF SEIZURES DURING SLEEP......Page 379
GENERALIZED EPILEPSIES ASSOCIATED WITH SEIZURES DURING DROWSINESS, SLEEP, OR UPON AWAKENING......Page 384
PARTIAL EPILEPSIES ASSOCIATED WITH SEIZURES DURING SLEEP......Page 387
C......Page 400
E......Page 401
H......Page 402
M......Page 403
O......Page 404
R......Page 405
S......Page 406
Z......Page 407