Site-Selective Neurotoxicity (Cellular and Molecular Mechanisms of Toxic Action)

Book Cover......Page 1
Title......Page 4
Contents......Page 5
List of figures......Page 10
List of tables......Page 13
List of contributors......Page 14
Preface to the series......Page 16
Preface......Page 18
Principles of neurotoxicology......Page 22
Site-selective action......Page 35
Molecular-specific actions......Page 46
Targets of free radical toxicity......Page 48
Neurotrophic factors and synaptic plasticity in the  adult hippocampus......Page 80
Cholinergic muscarinic receptors as targets for neurotoxicity......Page 97
Nicotinic acetylcholine receptors, beta-adrenergic receptors and  lung cancer......Page 113
Molecular neurotoxicology implications of  acetylcholinesterase inhibition......Page 135
Potassium channels......Page 153
Cellular-selective toxicity......Page 184
Motor neurons......Page 186
The cerebellar granule cell......Page 199
Purkinje cells: a significant target for neurotoxicity......Page 213
Neuronal degeneration in the forebrain produced by  amphetamine, methamphetamine and fenfluramine......Page 226
The astrocyte response to neural injury: a review and  reconsideration of key features......Page 252
Tissue-selective toxicity......Page 286
Detecting neurotoxic damage to the circumventricular  organs (CVOs): susceptible brain tissues located outside  the blood--brain barrier......Page 288
Mechanisms of peripheral neurotoxicity......Page 301
Index......Page 324