Seronegative spondyloarthritis. Ankylosing spondylitis: Study and methodological guide for 5th year students of Foreign Faculty

TABLE OF CONTENTS
INTRODUCTION
ABBREVIATIONS
DEFINITIONS
I. SERONEGATIVE SPONDYLOARTHRITIS
	Common signs of Seronegative spondyloarthritidies
	Pathological finding in Seronegative spondyloarthritidies
	Evaluation of Seronegative spondyloarthritidies
	Treatment of Seronegative spondyloarthritidies
	Conclusion
II.ANKYLOSING SPONDYLITIS
	Definition
	Relevance
	Epidemiology
	Etiology
	Pathogenesis
	CLINICAL PICTURE
		Clinical forms
		Axial lesions
		Extra-axial lesions
		Extra-skeletal lesions
		Stages of ankylosing spondylitis
		Factors of unfavorable prognosis
	DIAGNOSTICS OF ANKYLOSING SPONDYLITIS
		Physical examination
		Functional tests
		Functional indexes
		LABORATORY ANALYSIS
		INSTRUMENTAL METHODS
		Features of instrumental diagnostics at different stages of disease
	DIAGNOSTIC CRITERIA
	Disease activity
		BASDAI: Bath AS Disease Activity Index (Bath Ankylosing Spondylitis Disease Activity Index)
		ASDAS (The Ankylosing Spondylitis Disease Activity Score)
	Functional classes
	WRITING A DIAGNOSIS
	Indications for consulting rheumatologist
	Indications for consulting other specialists
	Indications for hospitalization
	DIFFERENTIAL DIAGNOSIS
	MANAGEMENT AND TREATMENT
		Basic principles of management [4]:
		Non-pharmacological treatment
		Drug therapy goals
		Non-steroidal anti-inflammatory drugs
		Analgesics
		Glucocorticoids
		Disease-modifying antirheumatic drugs
		Tumor necrosis factor-alpha inhibitors
		Other medicines
		Surgery
		PHARMACOTHERAPY FOR CHILDREN AND ADOLESCENTS
	DISEASE MONITORING
	PROGNOSIS
REFERENCE
TESTS
	Tests with one correct answer
	Tests with two or more correct answers
	TEST ANSWERS
CLINICAL CASES
	ANALYSIS OF CLINICAL CASE
	TRAINING CASES
	ANSWERS FOR TRAINING CASES
	INSTRUMENTAL DIAGNOSTICS CASES
	ANSWERS FOR INSTRUMENTAL DIAGNOSTICS CASES