Science

CONTENTS
NEWS IN BRIEF
	News at a glance
NEWS IN DEPTH
	Israel’s grim warning: Delta can overwhelm shots
	Nazi massacre unearthed in Poland ‘was really a horror’
	Laser-powered fusion effort nears ‘ignition’
	Dire warming report triggers calls for more action from China
	Antibody acts like short-term malaria vaccine
FEATURES
	Evolving threat
	Do chronic infections breed dangerous new variants?
POLICY FORUM
	Keep climate policy focused on the social cost of carbon
PERSPECTIVES
	The fracking concern with water quality
	Exploring the path of the variable resistance
	Tracking severe malaria disease
	Structural hierarchy defeats alloy cracking
	Ecology in the age of automation
BOOKS ET AL.
	The children’s climate crusade
	Before the Big Bang became scientific dogma
LETTERS
	Embrace kelp forests in the coming decade
	Mexico’s final death blow to the vaquita
	Piecing together an African peace park
RESEARCH IN BRIEF
	From <em>Science</em> and other journals
REVIEW
	Glaciohydrology of the Himalaya-Karakoram
RESEARCH ARTICLES
	A DNA repair pathway can regulate transcriptional noise to promote cell fate transitions
	Accurate prediction of protein structures and interactions using a three-track neural network
	Mechanisms that ensure speed and fidelity in eukaryotic translation termination
	Mammalian retrovirus-like protein PEG10 packages its own mRNA and can be pseudotyped for mRNA delivery
	Spatiotemporal invasion dynamics of SARS-CoV-2 lineage B.1.1.7 emergence
REPORTS
	Large-sample evidence on the impact of unconventional oil and gas development on surface waters
	Stabilizing perovskite-substrate interfaces for high-performance perovskite modules
	Spatiotemporal characterization of the field-induced insulator-to-metal transition
	Hierarchical crack buffering triples ductility in eutectic herringbone high-entropy alloys
	Rare variant <em>MX1</em> alleles increase human susceptibility to zoonotic H7N9 influenza virus
	Babbling in a vocal learning bat resembles human infant babbling
	Malaria infection and severe disease risks in Africa
	Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2
DEPARTMENTS
	Editorial
	Working Life
	<em>Science</em> Staff
	<em>Science</em> Careers